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Handbuch der psychiatrischen Pharmakotherapie pp 61–68Cite as

Prinzipien neuronaler Signalketten

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Zusammenfassung

Neuronale Signalketten dienen der Übertragung extrazellulärer, meist chemischer Signale in das Zellinnere. Einige zytoplasmatische Signale werden über die Kernmembran in den Zellkern übertragen, wodurch die Genexpression reguliert werden kann. Die physiologischen Wirkungen der Signale entfalten sich innerhalb weniger Millisekunden (meist nichtgenomische Wirkungen) oder innerhalb von Stunden bis Tagen (genomische Wirkungen). Als Komponenten neuronaler Signalketten wurden membranständige und intrazelluläre Proteine charakterisiert, die in zahlreichen Isoformen vorkommen.

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Author information

Authors and Affiliations

  1. Max-Planck-Institut für Medizinische Forschung, Molekulare Neurobiologie, Jahnstr. 29, 69120, Heidelberg

    PD Dr. Georg Köhr

Authors
  1. PD Dr. Georg Köhr
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Editor information

Editors and Affiliations

  1. Klinik für Psychiatrie, Psychotherapie und Psychosomatik, Pauwelsstr. 30, 52074, Aachen

    Gerhard Gründer

  2. Luisenstr. 19, 55124, Mainz

    Otto Benkert

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© 2012 Springer-Verlag Berlin Heidelberg

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Köhr, G. (2012). Prinzipien neuronaler Signalketten. In: Gründer, G., Benkert, O. (eds) Handbuch der psychiatrischen Pharmakotherapie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-19844-1_5

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  • DOI: https://doi.org/10.1007/978-3-642-19844-1_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-19843-4

  • Online ISBN: 978-3-642-19844-1

  • eBook Packages: Medicine (German Language)

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