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Nanosized and Nanoencapsulated Sunscreens

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Nanocosmetics and Nanomedicines

Abstract

Nanotechnology represents an important complement to traditional chromophore-based UV filters. Nanosized metal oxides are widely used due to their broad protection spectrum and reduced skin irritation. These particles are already present in most commercial sunscreen lotions even though their photoreactivity has been highlighted as a potential cause of cytotoxic effects in human skin cells (e.g. fibroblasts, epithelial cells). However, this cytotoxicity is not likely to represent a significant health risk to consumers as several skin penetration assays have shown that the photoreactive particles penetrate at most to the stratum spinosum of the epidermis. Nanoencapsulation of traditional organic UV filters is a more recent approach to improve skin retention, photostability and the UV blocking ability of the free molecules. All of these improvements have been confirmed with different scientific assays for different particles, especially polymeric nanocapsules and solid lipid nanoparticles. These technological advantages offered by nanometric particles for sun protection formulations have made them commercially important. In inventories from non-governmental organizations there are approximately 30 commercial sunscreen products listed as containing nanoparticles.

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Authors and Affiliations

  1. Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga, 2752, 90610-000, Porto Alegre, RS, Brazil

    Cássia B. Detoni, Karina Paese, Ruy C. R. Beck & Sílvia S. Guterres

  2. Departamento de Química Orgânica, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, CP 15003, 91501-970, Porto Alegre, RS, Brazil

    Adriana R. Pohlmann

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  1. Cássia B. Detoni
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  2. Karina Paese
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  3. Ruy C. R. Beck
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  4. Adriana R. Pohlmann
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  5. Sílvia S. Guterres
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  1. Dept. de Produção e Controle de Medicame, Faculdade de Farmácia, Federal University of Rio Grande do Sul, Av. Ipiranga 2752, 90610-000, Porto Alegre, Brazil

    Ruy Beck

  2. Faculty of Pharmacy, Dept. de Produção e Controle de Medicame, Federal University of Rio Grande do Sul, Av. Ipiranga 2752, 90610-000, Porto Alegre, Brazil

    Silvia Guterres

  3. Institut of Chemistry, Departamento de Química Orgânica, Federal University of Rio Grande do Sul, Av. Bento Gonçalves 9500, 91501-970, Porto Alegre, Brazil

    Adriana Pohlmann

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Detoni, C.B., Paese, K., Beck, R.C.R., Pohlmann, A.R., Guterres, S.S. (2011). Nanosized and Nanoencapsulated Sunscreens. In: Beck, R., Guterres, S., Pohlmann, A. (eds) Nanocosmetics and Nanomedicines. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-19792-5_17

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