Abstract
Hemolytic activity of single-head single-tail nonionic saccharide – derived surfactants (i.e., N-alkanoyl-N-methyllactitolamines and N-alkyl-N-methylaldonylamides) as well as dicephalic (i.e., (N-dodecyl-N,N-bis[(3-D-aldonylamido)propyl]amines; aldonyl = gluconyl and lactobionyl) and gemini structures (i.e., N,N’-bisdodecyl-N,N’-bis[(3-aldonylamide)propyl]ethylenediamines; aldonyl = gluconyl and lactobionyl) were examined and discussed in relation to both their critical micelle concentration (CMC) values, and structural aspects. The red blood cells lysis is found to depend on the surfactants structure and the hydrophobic tail length, as well as to correlate well with the CMC magnitudes.
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References
Carnero Ruiz C (2008) Sugar-based surfactants. Fundamentals and applications. Taylor & Francis, New York
Claesson M, Kjellin URM (2006) Sugar surfactants in: P. Somasundaran, A. Hubbard (Eds), Encyclopedia of Surface and Colloid Science, Taylor & Francis, New York
Wilk KA, Syper L, Domagalska BW, Komorek U, Maliszewska I, Gancarz R (2001) J Surfactants Deterg 5:235
Burczyk B, Wilk KA, Sokołowski A, Syper L (2001) J Colloid Interface Sci 240:552
Komorek U, Wilk KA (2004) J Colloid Interface Sci 271:206
Söderlind E, Wollbratt M, von Corswant C (2003) Int J Pharm 252:61
Li X, Turánek J, Knötigová P, Kudlačkowá H, Mašek J, Parkin S, Rankin SE, Knutson BL, Lehmler HJ (2009) Colloids Surf B 73:65
Neimert-Andersson K, Sauer S, Panknin O, Borg T, Söderlind E, Somfai P (2006) J Org Chem 70:3623
Söderlind E, Karlsson L (2006) Eur J Pharm Biopharm 62:254
Wilk KA, Syper L, Burczyk B, Maliszewska I, Jon M, Domagalska BW (2001) J Surfactants Deterg 4:155
Wilk KA, Syper L, Burczyk B, Sokołowski A, Domagalska BW (2000) J Surfactants Deterg 3:185
Pietkiewicz J, Zielińska K, Saczko J, Kulbacka J, Majkowski M, Wilk KA (2010) Eur J Pharm Sci 39:322
Prete PSC, Gomes K, Malheiros SVP, Meirelles NC, de Paula E (2002) Biophys Chem 97:45
Harada S, Sahara H (1994) Langmuir 10:4073
Kawaizumi F, Kuzuhara T, Nomura H (1998) Langmuir 14:3749
Mc Gowan J (1990) Tenside Surfact Det 27:229
Acknowledgement
This work was supported by Department of Chemistry, Wroclaw University of Technology, Poland and Wroclaw Research Center EIT+ under the project „Biotechnologies and advanced medical technologies" – BioMed (POIG 01.01.02-02-003/08-00) financed from the European Regional Development Fund (Operational Programme Innovative Economy, 1.1.2)
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Wilk, K.A., Zielińska, K., Jarzycka, A., Pietkiewicz, J. (2011). Human Erythrocyte Hemolysis Induced by Bioinspired Sugar Surfactants. In: Starov, V., Procházka, K. (eds) Trends in Colloid and Interface Science XXIV. Progress in Colloid and Polymer Science, vol 138. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-19038-4_34
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DOI: https://doi.org/10.1007/978-3-642-19038-4_34
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