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Entwicklung von Extrusionspellets

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Arzneiformen-Entwicklung

Part of the book series: Springer-Lehrbuch ((SLB))

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Zusammenfassung

Im Arzneibuch werden kugelförmige Aggregate aus festen Einzelteilchen — u. a. Arzneistoffen — Pellets genannt und der Monographie „Granulate“ zugeordnet. Von den üblichen Granulaten unterscheiden sich Pellets — außer in der Form — in der scheinbaren Dichte, d. h. Pellets sind etwas dichter als Granulate. Sie sind meist Zwischenprodukte, da sie überwiegend mit Polymerhüllen versehen werden. Die geringe Größe der Pellets gewährleistet eine rasche Magenpassage sowie eine breite Verteilung im Darmtrakt.

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  1. Institut für Pharmazeutische Technologie und Biopharmazie, Universität Heidelberg, Richard-Lenel-Weg 13a, 69151, Neckargemünd, Deutschland

    Professor Dr. Herbert Sticker

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Sticker, H. (2003). Entwicklung von Extrusionspellets. In: Arzneiformen-Entwicklung. Springer-Lehrbuch. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18982-1_4

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