Functional Brain Imaging in Personality Research and Personality Disorders

  • Kurt Audenaert
  • Ingeborg Goethals
  • Kathelijne Peremans
  • Andreas Otte
  • F. Van Den Eynde
  • Kris H. Naudts
  • Myriam Vervaet
  • Rudi Dierckx
  • Kees van Heeringen


Personality traits can be defined as stable and enduring patterns of perceiving, relating to, and thinking about the environment and oneself. Only when personality traits are inflexible and maladaptive and cause significant functional impairment or subjective distress will they constitute personality disorders. The Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR), representing the widely accepted classification system of mental disorders, designates personality disorders (PD) to axis II. Ten well-circumscribed personality disorders are therein defined and allocated to three clusters (A, B and C). Besides the categorical diagnostic approach in the DSM-IV classification system, there is a robust line of research that is dimensional in nature. Dimensional personality models include Cloninger’s Temperament and Character model, the Five-Factor Model and the Karolinska Personality Model. An overview of brain perfusion and metabolism studies and receptor ligand studies is presented. When appropriate, links to clinical applications are discussed.


Borderline Personality Disorder Personality Disorder Personality Disorder Harm Avoidance Borderline Personality Disorder 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2004

Authors and Affiliations

  • Kurt Audenaert
    • 1
  • Ingeborg Goethals
    • 2
  • Kathelijne Peremans
    • 3
  • Andreas Otte
    • 2
  • F. Van Den Eynde
    • 1
  • Kris H. Naudts
    • 1
  • Myriam Vervaet
    • 1
  • Rudi Dierckx
    • 2
  • Kees van Heeringen
    • 1
  1. 1.Department of Psychiatry and Medical PsychologyUniversity Hospital GhentGentBelgium
  2. 2.Division of Nuclear MedicineUniversity Hospital GhentGentBelgium
  3. 3.Faculty of Veterinary MedicineDepartment of Medical ImagingMerelbekeBelgium

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