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Erythropoietin: A Beneficial Approach to Neuroprotection in Stroke

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Maturation Phenomenon in Cerebral Ischemia V

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Abstract

Erythropoietin (EPO) was first characterized as a hematopoietic growth factor and has been in clinical use as such for more than a decade. The expression of EPO and its receptor in brain tissue, cultured neurons and astrocytes along with its neuroprotective potential in several experimental models of stroke expands its biological role beyond hematopoiesis [1–5].

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References

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Authors
  1. H. Ehrenreich
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  2. A. L. Sirén
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Editor information

Editors and Affiliations

  1. Office of Stroke Research, Foothills Medical Centre, Rm 1162, 1403-29 Street N.W., Calgary, Alberta, T2N 2T9, Canada

    Alastair M. Buchan

  2. Department of Neurosurgery, Musashino Red Cross Hospital, 1-26-1 Kyonan-cho, Musashino-shu, Tokyo, 180-0023, Japan

    Umeo Ito

  3. Department of Psychology, University of Alberta, Edmonton, Alberta, T6G 2E9, Canada

    Fred Colbourne

  4. Department of Neuropathology Medical Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku 113, Tokyo, Japan

    Toshihiko Kuroiwa

  5. Laboratory of Neuropathology and Neuroanatomical Sciences, NINDS, National Institutes of Health, Bethesda, Maryland, 20892-4128, USA

    Igor Klatzo

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© 2004 Springer-Verlag Berlin Heidelberg

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Ehrenreich, H., Sirén, A.L. (2004). Erythropoietin: A Beneficial Approach to Neuroprotection in Stroke. In: Buchan, A.M., Ito, U., Colbourne, F., Kuroiwa, T., Klatzo, I. (eds) Maturation Phenomenon in Cerebral Ischemia V. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18713-1_6

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  • DOI: https://doi.org/10.1007/978-3-642-18713-1_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-40874-1

  • Online ISBN: 978-3-642-18713-1

  • eBook Packages: Springer Book Archive

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