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Ischemic Preconditioning Prevents Global Ischemia-Induced Downregulation of the AMPA Receptor GluR2 Subunit in the Hippocampal CA1 but does not Block Caspase-3 Activation nor Protect against GluR2 Antisense Knockdown

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Maturation Phenomenon in Cerebral Ischemia V

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Abstract

Animals subjected to sublethal transient global ischemia (preconditioning) exhibit neuroprotection against subsequent global ischemia-induced neuronal death in the hippocampal CAI (ischemic tolerance). The molecular mechanisms underlying ischemic tolerance are, however, unclear

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Author information

Authors and Affiliations

  1. Department of Neuroscience, Albert Einstein College, 1300 Morris Park Avenue, Kennedy 720, Bronx, New York, 10461, USA

    Dr. M. V. L. Bennett

Authors
  1. H. Tanaka
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  2. A. Calderone
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  3. T. Jover
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  4. S. Y. Grooms
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  5. R. S. Zukin
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  6. Dr. M. V. L. Bennett
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Editor information

Editors and Affiliations

  1. Office of Stroke Research, Foothills Medical Centre, Rm 1162, 1403-29 Street N.W., Calgary, Alberta, T2N 2T9, Canada

    Alastair M. Buchan

  2. Department of Neurosurgery, Musashino Red Cross Hospital, 1-26-1 Kyonan-cho, Musashino-shu, Tokyo, 180-0023, Japan

    Umeo Ito

  3. Department of Psychology, University of Alberta, Edmonton, Alberta, T6G 2E9, Canada

    Fred Colbourne

  4. Department of Neuropathology Medical Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku 113, Tokyo, Japan

    Toshihiko Kuroiwa

  5. Laboratory of Neuropathology and Neuroanatomical Sciences, NINDS, National Institutes of Health, Bethesda, Maryland, 20892-4128, USA

    Igor Klatzo

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© 2004 Springer-Verlag Berlin Heidelberg

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Tanaka, H., Calderone, A., Jover, T., Grooms, S.Y., Zukin, R.S., Bennett, M.V.L. (2004). Ischemic Preconditioning Prevents Global Ischemia-Induced Downregulation of the AMPA Receptor GluR2 Subunit in the Hippocampal CA1 but does not Block Caspase-3 Activation nor Protect against GluR2 Antisense Knockdown. In: Buchan, A.M., Ito, U., Colbourne, F., Kuroiwa, T., Klatzo, I. (eds) Maturation Phenomenon in Cerebral Ischemia V. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18713-1_32

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  • DOI: https://doi.org/10.1007/978-3-642-18713-1_32

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-40874-1

  • Online ISBN: 978-3-642-18713-1

  • eBook Packages: Springer Book Archive

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