Zusammenfassung
Seit der Einführung des Belastungs-EKG in den frühen 30er-Jahren (Goldhammer u. Scherf 1932; Dietrich u. Schwiegk 1933) entwickelte sich diese Untersuchungsmethode zu einer der brauchbarsten diagnostischen Hilfen für die objektive und quantitative Erfassung der Belastungskoronarinsuffizienz.
Pathophysiologisch liegt der Belastungskoronarinsuffizienz ein vorübergehendes Missverhältnis zwischen Sauerstoffangebot und -bedarf zugrunde. Morphologisch liegt bei der überwiegenden Anzahl der Patienten eine stenosierende Koronarsklerose vor. Die Koronarangiographie hat wesentlich dazu beigetragen, die Interpretation des Belastungs-EKG zu verbessern. Dabei darf man aber nicht vergessen, dass zwischen beiden Methoden ein grundsätzlicher Unterschied besteht: Die Koronarangiographie erfasst die morphologischen Veränderungen der Herzkranzgefäße, das Belastungs-EKG die funktionellen Auswirkungen (Dynamik der Stenose, Durchblutung über Kollateralen, Koronarreserve).
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Literatur
AHA Medical-Scientific Statement, Special Report (1990) Exercise standards: a statement for health professionals from the American Heart Association. Circulation 82:2286
American College of Cardiology/American Heart Association (2002) Guideline update for exercise testing. J Am Coll Cardiol 40:1531
Amsterdam E, Krik DB, Diercks D et al (2002) Immediate exercise testing to evaluate low-risk patients presenting to the emergency department with chest pain. J Am Coll Cardiol 40:25–26
Asokan SK, Fraser RC, Kolbeck RC, Frank MJ (1975) Variations in right and left coronary blood flow in men with and without occlusive coronary disease. Brit Heart J 37:604
Bargheer K, Trappe HJ, Wenzlaff P, Lichtlen PR (1993) Langzeitverlauf von Patienten mit Angina-pectoris-ähnlichen Brustschmerzen und normalem Koronarangiogramm. Z Kardiol 82:8
Bartel AG, Behar VS, Peter RH et al (1973) Exercise stress testing in evaluation of aortocoronary bypass surgery report of 123 patients. Circulation 48:141
Bengtsson C, Grimby G, Lindquist O et al (1981 ) Prognosis of women with exercise-induced ECG changes-results from a longitudinal population study. Cardiology 68 (Suppl 2):9
Berenyi I, Hajduczki IS, Böszörmenyi E (1984) Quantitative evaluation of exercise-induced ST-segment depression for estimation of degree of coronary artery disease. Europ Heart J 5:289
Blackburn H (1969) The exercise electrocardiogram.Technological, procedural and conceptual developments. In: Blackburn H (ed) Measurement in exercise electrocardiography, p 220. Thomas CC, Springfield/Ill
Blackburn H, Taylor HL, Hamrell B et al (1979) Premature ventricular complexes induced by stress testing. Am J Cardiol 31:441
Block TA, Murray JA, English MT (1977) Improvement in exercise performance after unsuccessful myocardial revascularization. Am J Cardiol 40:673
Bruce RA, Blackmon Jr, lones JW, Srait G (1963) Exercise testing adult normal subjects and cardiac patients. Pediatrics 32:742
Bugiardini R, Borghi A, Bragetti L, Puddui P (1989) Comparisan of verapamil versus propranolol therapy in syndrome X. Am J Cardiol 63:286
Cannon RO, Watson RM, Rosing DR, Epstein SE (1983) Angina caused by reduced vasodilator reserve of the small coronary arteries. J Am Coll Cardiol 1:1359
Cannon RO, Epstein SE (1988) „Microvascular angina“ as a cause of chest pain with angiographically normal coronary arteries. Am J Cardiol 61:1338
Case RB, Masser MG, Crampton RS (1969) Biochemical aspects of early myocardial ischemia. Am J Cardiol 24:766
Chaitman BR, Bourassa MG, Wagniart P et al (1978) Improved efficiency of treadmill exercise testing using a multiple lead ECG system and basic hemodynamic exercise response. Circulation 57:71
Chaitman BR, Hanson JS (1981) Comparative sensitivity and specificity of exercise electrocardiographic lead systems. Amer J Cardiol 47:1335
Chauhan A, Petch MC, Schofield PM (1993) „Syndrome X“ and coronary arterydisease. Coronary Artery Disease 4:555
Cole CR, Blackstone EH, Pashkow F et al (1999) Hart rate recovery immediately after exercise as a predictor of mortality. N Engl J Med 341:1351–1357
Crow SR, Campbell S, Prineas RJ (1978) Accurate automatic measurement of ST-segment response in the exercise electrocardiogram. Comput Biomed Res 11:243
Dargie HJ for the ESC Working Group on Exercise Physiology, Physiopathology and Electrocardiography (1993) Guidelines for cardiac exercise testing. Eur Heart J 14:969
Dean JD, lones CJH, Hutchinson SI, Peters Jr, Henderson AH (1991 ) Hyperinsulinaemia and microvascular angina („syndrome X“). Lancet 337:456
De Caprio L, Duomo S, Vigorito C et al (1983) Exercise induced ventricular arrhythmias: angiographic correlation with the severity of coronary artery disease. Jpn Heart J 24:489
Detry JMR (1972) Exercise testing and training in coronary heart disease. Thesis by Jean-Marie R Detry, Kroese ST (ed) Williams & Wilkins, Leiden
Diamond GA, Forrester JS (1979) Analysis of probability as an aid in the clinical diagnosis of coronary-artery disease. N Engl J Med 300:1350
Dietrich S, Schwiegk H (1933) Angina pectoris und Anoxie des Herzmuskels. Z klin Med 125:195
Ellestad MH (1986) Stress testing. Principles and practice, 3rd ed. Davis FA, Philadelphia
Ellestad MH, Wan MKC (1975) Predictive implications of stress testing follow-up of 2700 subjects after maximum treadmill stress testing. Circulation 51:363
Epstein SE (1980) Implications of probabilityanalysis on the strategy used for noninvasive detection of coronary artery disease. Role of single or combined use of exercise electrocardiographic testing, radionuclide cineangiography and myocardial perfusion imaging. Amer J Cardiol 46:491
Erikssen J, Enge I, Forfang K et al (1976) False-positive diagnostic tests and coronary angiographic findings in 105 presumably healthy males. Circulation 54:371
Fioretti P, Brower RW, Simoons ML (1986) Relative value of clinical variables, bicycle ergometry, rest radionuclide ventriculography and 24 hour ambulatory electrocardiographic monitoring at discharge to predict 1 year survival after myocardial infarction. J Amer Coll Cardiol 8:40
Forlini FJ Jr, Dohn K, Langston MF Jr (1975) ST-segment isolation and quantification as a means of improving diagnostic accuracy in treadmill stress testing. Amer Heart J 90:431
Franz IW (1979) Untersuchungen über das Blutdruckverhalten während und nach Ergometrie bei Grenzwerthypertonikern im Vergleich zu Normalpersonen und Patienten mit stabiler Hypertonie. Z Kardiol 68:107
Froelicher VF, Myers J (199) Exercise and the heart, 4th ed. Saunders, Sidcup UK
Froelicher VG, Thomas MM, Pillow C (1974) Epidemiologic study of asymptomatic men screened by maximal treadmill testing for latent coronary artery disease. Am J Cardiol 34:770
Fuller CM, Raizner AE, Verani MS et al (1981) Early postmyocardial infarction treadmill stress testing. An accurate predictor of multivessel coronary disease and subsequent cardiac events. Ann Intern Med 94:734
Galassi AR, Kaski JC, Pupita G et al (1989) Lack of evidence for alpha-adrenergic receptor-mediated mechanisms in the genesis of ischemia in syndrome X. Am J Cardiol 64:264
Georgopoulos AJ, Proudfit WL, Page IH (1961 ) Effect of exercise on electrocardiograms of patients with low serum potassium. Circulation 23:567
Gerson MC, Morris SN, McHenry PL (1980) Relation of exercise-induced physiologic S-T segment depression of R-wave amplitude in normal subjects. Am J Cardiol 46:778
Goldhammer S, Scherf D (1932) Elektrokardiographische Untersuchungen bei Kranken mit Angina pectoris. Z klin Med 122:134
Gordon DJ, Ekelund LG, Karon JM et al (1986) Predictive value of the exercise tolerance test for mortality in North American men: The lipid research clinics mortality follow-up study. Circulation 74:252
Gould KL, Lipscomb K, Hamilton GW (1974) Physiologic basis for assessing critical coronary stenosis. Amer J Cardiol 33:87
Grobecker H (1982) Sympathische Regulation des Koronarkreislaufs. In: Roskamm H, Holzgreve H (Hrsg) Die Beta-Rezeptorenblockade aus pathophysiologischer Sicht. Schattauer, Stuttgart New York, S 1–11
Hecht HS, DeBord L, Shaw R et al (1993) Usefulness of supine bicycle stress echocardiography for detection of restenosis after percutaneous transluminal coronary angiography. Am J Cardiol 71:293
Hess OM, Buchi M, Kirkeeide R et al (1990) Potential role of coronary vasocionstriction in ischaemic heart disease: Effect of exercise. Eur Heart J 11(Suppl B):58
Hochrhein H, Lehmann HU, Helwing HP (1975) EKG-Veränderungen bei Coronarinsuffizienz und unter dem Einfluss von Digitalis. Klinikarzt 4:403
Hossack KF, Bruce RA (1985) Prognostic value of exercise testing: The Seattle heart watch experience. J Cardiac Rehabil 5:9
Jaffe DM (1977) Effect of oestrogenes on electrocardiogram. Brit Heart J 38:1299
Jungmann E, Schulz W, Kober G et al (1981) Folgen des regelmäßigen Laxantiengebrauchs. Münch Med Wochenschr 123:965
Kadel C, Strecker T, Kaltenbach M, Kober G (1989) Recognition of restenosis: can patients be defined in whom the exerciseECG result makes angiography restudy unnecessary? Eur Heart J 10 (Suppl G):22
Kaltenbach M (1974) Die Belastungsuntersuchung von Herzkranken. Kardiologische Diagnostik. Boehringer, Mannheim
Kaltenbach M, Klepzig H, Tschirdewahn B (1964) Die Kletterstufe, eine einfache Vorrichtung für exakt meßbare und reproduzierbare Belastungsuntersuchungen. Med Klin 59:248
Kawai C, Hultgren HN (1964) The effect of digitalis upon the electrocardiogram. Amer Heart J 68:409
Kemp HG (1973) Left ventricular function in patients with the anginal syndrome and normal coronary arteriograms. Am J Cardiol 32:375
Kemp HG, Vokonas PS, Cohn PF, Gorlin R (1973) The anginal syndrome associated with normal coronary arteriograms: report of six-year experience. Am J Med 54:735
Klepzig H (1976) Belastungsprüfungen von Herz und Kreislauf. Kurzmonographien, Sandoz 16
Lauer MS, Alexe CE, Pothier Snader CE et al (2002) Use of the logical analysis of data method fro assessing longterm mortality risk after exercise electrocardiography. Circulation 106:685–690
Likoff W, Segal BL, Kasparian H (1967) Paradox of normal selective coronary arteriograms in patients considered to have unmistakable coronary heart disease. N Engl J Med 276:1063
Löllgen H, Erdmann E (Hrsg) (2000) Ergometrie, 3. Aufl. Springer, Berlin Heidelberg New York
Löllgen H, Ulmer HV (1985) Ergometrie-Empfehlungen zur Durchführung und Bewertung ergometrischer Untersuchungen. Ergebnisbericht einer Klausurtagung in Titisee. 7./8.12.1984. Klin Wochenschr 63:651
Maseri A (1976) Pathophysiologic studies of the pulmonary and coronary circulations in man. Am J Cardiol 38:751
McConahay DR, McCallister BD, Smith RE (1971) Postexercise electrocardiography: Correlations with coronary arteriography and left ventricular hemodynamics. Amer J Cardiol 28:1
McConahay DR, Valdes M, McCallister BD et al (1977) Accuracy of treadmill testing in assessment of direct myocardial revascularization. Circulation 56:8
Motz W, Vogt M, Rabenay O et al (1991 ) Evidence of endothelial dysfunction in coronary resistance vessels in patients with angina pectoris and normal coronary angiograms. Am J Cardiol 68:996
Multiple Risk Factor Intervention Irial Research Group: Exercise electrocardiogram and coronary heart disease mortality in the multiple risk factor intervention trial. Amer J Cardiol 55:16
Nair CK, Thomson W, Aronow WS et al (1984) Prognostic significance of exercise-induced complex ventricular arrhythmias in coronary artery disease with normal and abnormal left ventricular ejection fraction. Am J Cardiol 54:1136
Okin PM, Ameisen O, Kligfield P (1986) A modified treadmill exercise protocol for computer-assisted analysis of the ST-segment/heart rate slope: Methods and reprodicibility. J Electrocardiol 19:B11
Opherk D, Zebe H, Weihe E et al (1981) Das Syndrom pektanginöser Beschwerden bei Patienten mit normalem Koronarangiogramm (Syndrom X). Dtsch Med Wochenschr 106:1686
Parker JO, West RO, Case RB, Chong MA (1969a) Temporal relationships of myocardiallactate metabolism, left ventricular function, and ST-segment depression during angina precipitated by exercise. Circulation 40:97
Parker JO, Chong MA, West RO, Case RB (1969b) Sequential alterations in myocardial lactate metabolism, ST-segments, and left ventricular function during angina induced by atrial pacing. Circulation 40:113
Phillips RE (1974) The interaction of exercise and drugs. In: Zohman LR, Phillips RE (eds) Progress in cardiac rehabilitation. Thieme, Stuttgart, p104
Pryor DB, Harreil FE, Leehl Califf RM, Rosati RA (1983) Estmating the likelihood of significant coronary artery disease. Am J Med 75:771
Rautaharju PM, Prineas Rl, Crow RS et al (1980) The effect of modified limb electrode positions on electrocardiographic wave amplitudes. J Electrocardiol 2:109
Roskamm H (1968) Das Belastungs-EKG. Boehringer, Mannheim
Roskamm H, Samek L, Zweigle K et al (1977) Die Beziehungen zwischen den Befunden der Coronarangiographie und des Belastungs-EKG bei Patienten ohne transmuralen Myokardinfarkt. Z Kardiol 66:273
Roskamm H, Schmuziger M, Stürzenhofecker P et al (1986) Bestimmt die Vollständigkeit der Revaskularisation die funktionelle Verbesserung und die Überlebensdaten koronaroperierter Patienten? Ergebnisse von 1000 konsekutiv operierten Patienten. Z Kardiol 70:590
Samek L, Roskamm H, Rentrop P et al (1975) Belastungsprüfungen und Coronarangiogramm im chronischen Infarktstadium. Z Kardiol 64:809
Samek L, Meister G, Roskamm H et al (1977) Herzrhythmusstörungen nach Herzinfarkt. Herz Kreislauf 9:641
Samek L, Meister G, Roskamm H (1981) Sind Angina pectoris und ischämische ST-Senkung während Belastung bei Frauen unsichere Ischämiekriterien? (Abstr) Z Kardiol 70:629
Samek L, Roskamm H (1983) Das Belastungs-EKG bei Frauen: schwerer zu beurteilen, aber doch diagnostisch aussagekräftig. Med Klin Prax 78:21
Samek L, Roskamm H (1984) Belastungs-EKG. In: Roskamm H (Hrsg) Handbuch der inneren Medizin. Bd IX/3: Koronarerkrankungen. Springer, Berlin Heidelberg New York Tokyo, S 277
Samek L, Hirsch F, Roskamm H (1985) Mit welchen Koronarbefunden muß man bei hoch positivem Belastungstest-AP und ischämische ST-Senkung bei 25 Watt rechnen? Z Kardiol 74(Suppl 3):32
Samek L, Roskamm H (1987) Bedeutung und Wertigkeit des Belastungs-EKG bei koronarkranken Frauen. In: Weidemann H (Hrsg) Die koronare Herzkrankheit der Frau. Steinkopff, Darmstadt, S 81
Santinga JT, Brymer JF, Smith F, Flora J (1977) The influence of lead strength on the ST changes with exercise electrocardiography (correlative study with coronary angiography). J Electrocardiol 4:387
Saunamaeki Kl, Andersen JD (1981) Early exercise test in the assessment of lang-term prognosis after acute myocardial infarction. Acta Med Scand 209:185
Scherer D, Kaltenbach M (1979) Häufigkeit lebensbedrohlicher Komplikationen bei ergometrischen Belastungsuntersuchungen. Z Kardiol 68:240
Schroeder E, Marchandise B, De Coster P et al (1989) Detection of restenosis after coronary angioplasty for single-vessel disease: how reliable are exercise electrocardiography and scintigraphy in asymptomatic patients? Eur Heart J 10(Suppl G):18
Schüren KP, Behrens P, Schröder R (1978) Falsch positives Belastungs-EKG bei organisch gesunden Frauen. Dtsch Med Wochenschr 103:816
Schwartz KM, Turner JD, Sheffield LT et al (1981) Limited exercise testing soon after myocardial infarction. Correlation with early coronary and left ventricular angiography. Ann Intern Med 94:727
Simoons ML (1977) Optimal measurement für detection of coronary artery disease by exercise electrocardiography. Comput Biomed Res 10:483
Shephard RJ, Miller HS (1999) Exercise and the heart in health and disease. Dekker, New York
Sionis D, Vrolix MC, Glazier JJ et al (1992) Early exercise testing after successful percutaneous transluminal coronary angioplasty: a ward of caution. Am Heart J 123:530
Staniloff HM, Diamond GA, Pollock BH (1984) Probabilistic diagnosis and prognosis of coronary artery disease. J Cardiac Rehabil 4:518
Stuart RJ, Ellestad MH (1976) Upsloping ST-segments in exercise stress testing. Six year follow-up study of 438 patients and correlation with 248 angiograms. Am J Cardiol37:19
Stücker TD, Burweil LR, Nygaard TW et al (1989) Quantative exercise thallium-201 scintigraphy für predicting angina recurrence after percutaneous transluminal coronary angioplasty. Am J Cardiol 63:517
Théroux P, Waters DD, Halphen C et al (1979) Prognostic value of exercise testing soon after myocardial infarction. N Engl J Med 301:341
Thompson PD (2001) Exercise and sports cardiology. McGraw Hill, New York
Trappe HJ, Löllgen H (2000) Leitlinien zur Ergometrie. Z Kardiol 98: 821–857
Tubau JF, Chaitman BR, Bourasse MG, Waters DD (1980) Detection of multivessel coronary disease after myocardial infarction using exercise stress testing multiple ECG lead systems. Circualtion 61:44
Velasco J, Tormo V, Ferrer LM et al (1981 ) Early exercise test für evaluation of long-term prognosis after uncomplicated myocardial infarction. Europ Heart J 2:401
Zwillinger L (1935) Die Digitaliswirkung auf das Arbeits-Elektrokardiogramm. Med Klin 30:977
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Samek, L., Roskamm, H., Löllgen, H. (2004). Belastungs-EKG. In: Roskamm, H., Neumann, FJ., Kalusche, D., Bestehorn, HP. (eds) Herzkrankheiten. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18649-3_10
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