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Antiinfektive Therapie

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Zusammenfassung

Die antimikrobielle Chemotherapie ist definiert als eine selektiv auf den Erreger wirkende Zerstörung oder Wachstumshemmung unter weitgehender Schonung der körpereigenen Zelle. Eine Trennung in die synthetisch gewonnenen Chemotherapeutika und die von Pilzen oder Bakterien gebildeten Antibiotika ist heute nicht mehr strikt aufrecht zu erhalten, da zahlreiche Antibiotika voll- oder halbsynthetisch hergestellt werden. Die Einteilung erfolgt nach der chemischen Struktur in Substanzgruppen mit meist ähnlichem Verhalten hinsichtlich Wirkungsmechanismus, Wirkungsspektrum, Erregerpersistenz und Toxizität.

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D., A. et al. (2004). Antiinfektive Therapie. In: Adam, D., Doerr, H.W., Link, H., Lode, H. (eds) Die Infektiologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18577-9_5

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