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Chlamydien

  • Chapter
Die Infektiologie

Zusammenfassung

Chlamydien sind obligat intrazelluläre, unbewegliche gramnegative Bakterien. Sie gehören einer eigenen Ordnung, den Chlamydiales, und innerhalb dieser Ordnung der Familie Chlamydiaceae an. Nach dem Vorschlag von Everett et al. (1999) werden anhand von 16S- und 23S-RNA-Analysen die 5 Genera Chlamydia, Chlamydophila, Parachlamydia, Simkania und Waddlia unterschieden ( vgl.Tabelle 26-1 ). Diese Nomenklatur wird von Chlamydologen aus populationsgenetischen Gründen nicht akzeptiert. Deshalb wird es weiterhin die Bezeichnungen Chlamydia psittaci und Chlamydia pneumoniae geben (Schachter et al. 2001)

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Literatur

  • Apfalter P, Boman J, Nehr M et al. (2001) Application of blood-based polymerase chain reaction for detection of chlamydia pneumoniae in acute respiratory tract infections. Eur J Clin Microbiol Infect Dis 20/8:584–586

    Article  PubMed  CAS  Google Scholar 

  • Bachmaier K, Neu N, de la Maza LM, Pal S, Hessel A, Penninger JM (1999) Chlamydia infections and heart disease linked through antigenic mimicry. Science 283(5406): 1335–1339

    Article  PubMed  CAS  Google Scholar 

  • Bannantine JP, Stamm WE, Suchland RJ, Rockey DD (1998) Chlamydia trachomatis IncA is localized to the inclusion membrane and is recognized by antisera from infected humans and primates. Infect Immun 66/12:6017–6021

    PubMed  CAS  Google Scholar 

  • Bardin T, Enel C, Cornelis F, Salski C, Jorgensen C, Ward R, Lathrop GM (1992) Antibiotic treatment of venereal disease and Reiter’s syndrome in a Greenland population. Arthritis Rheum 35/2:190–194

    Article  PubMed  CAS  Google Scholar 

  • Beatty WL, Morrison RP, Byrne Gl (1995) Reactivation of persistent chlamydia trachomatis infection in cell culture. Infect Immun 63/1:199–205

    PubMed  CAS  Google Scholar 

  • Berlau J, Junker U, Groh A, Straube E (1998) In situ hybridisation and direct fluorescence antibodies for the detection of chlamydia trachomatis in synovial tissue from patients with reactive arthritis. J Clin Pathol 51/11:803–806

    Article  PubMed  CAS  Google Scholar 

  • Black CM (1997) Current methods of laboratory diagnosis of chlamydia trachomatis infections. Clin Microbiol Rev 10/1:160–184

    PubMed  CAS  Google Scholar 

  • Campbell LA, Perez Melgosa M, Hamilton DJ, Kuo CC, Grayston JT (1992) Detection of chlamydia pneumoniae by polymerase chain reaction. J Clin Microbiol 30/2:434–439

    PubMed  CAS  Google Scholar 

  • Chernesky M, Smieja M, Schachter J et al. (2002) Comparison of an industry-derived LCx chlamydia pneumoniae PCR research kit to in-house assays performed in five laboratories. J Clin Microbiol 40/7:2357–2362

    Article  PubMed  CAS  Google Scholar 

  • Domeika M, Bassiri M, Butrimiene I, Venalis A, Ranceva J, Vasjanova V (1999) Evaluation of vaginal introital sampling as an alternative approach for the detection of genital chlamydia trachomatis infection in women. Acta Obstet Gynecol Scand 78/2:131–136

    Article  PubMed  CAS  Google Scholar 

  • Dowell SF, Peeling RW, Boman J et al. (2001) C. pneumoniae Workshop Participants Standardizing chlamydia pneumoniae assays: recommendations from the Centers for Disease Control and Prevention (USA) and the Laboratory Centre for Disease Control (Canada). Clin Infect Dis 33/4:492–503

    Article  PubMed  CAS  Google Scholar 

  • Everett KD, Bush RM, Andersen AA (1999) Emended description of the order chlamydiales, proposal of Parachlamydiaceae fam. nov. and Simkaniaceae fam. nov., each containing one monotypic genus, revised taxonomy of the family chlamydiaceae, including a new genus and five new species, and standards for the identification of organisms. Int J Syst Bacteriol 49 Pt 2:415–440

    Article  Google Scholar 

  • Fan T, Lu H, Hu H, Shi L et al. (1998) Inhibition of apoptosis in chlamydia-infected cells: blockade of mitochondrial cytochrome c release and caspase activation. J Exp Med 187/4:487–496

    Article  PubMed  CAS  Google Scholar 

  • Gaydos CA, Quinn TC, Eiden JJ (1992) Identification of chlamydia pneumoniae by DNA amplification of the 16S rRNA gene. J Clin Microbiol 30/4:796–800

    PubMed  CAS  Google Scholar 

  • Gerard HC, Branigan PJ, Schumacher HR Jr, Hudson AP (1998) Synovial chlamydia trachomatis in patients with reactive arthritis/Reiter’s syndrome are viable but show aberrant gene expression. J Rheumatol 25/4:734–742

    PubMed  CAS  Google Scholar 

  • Hahn DL (1999) Chlamydia pneumoniae, asthma, and COPD: what is the evidence? Ann Allergy Asthma Immunol 83/4:271–288

    Article  PubMed  CAS  Google Scholar 

  • Klaus V (1996) In: Lang W (Hrsg) Tropenmedizin in Klinik und Praxis. Thieme, Stuttgart

    Google Scholar 

  • Knudsen K, Madsen AS, Mygind P, Christiansen G, Birkelund S (1999) Identification of two novel genes encoding 97-to 99-kilodalton outer membrane proteins of chlamydia pneumoniae. Infect Immun 67/1:375–383

    PubMed  CAS  Google Scholar 

  • Kuoppa Y, Boman J, Scott L, Kumlin U, Eriksson I, Allard A (2002) Quantitative detection of respiratory chlamydia pneumoniae infection by real-time PCR. J Clin Microbiol 40/6:2273–2274

    Article  PubMed  CAS  Google Scholar 

  • Lehmann M, Groh A, Rödel J, Nindl I, Straube E (1999) Detection of chlamydia trachomatis DNA in cervical samples with regard to infection by human papillomavirus. J Infect 38/1:12–17

    Article  PubMed  CAS  Google Scholar 

  • Maass M, Bartels C, Engel PM, Mamat U, Sievers HH (1998) Endovascular presence of viable chlamydia pneumoniae is a common phenomenon in coronary artery disease. J Am Coll Cardiol 31/4:827–832

    Article  PubMed  CAS  Google Scholar 

  • Mahony J, Chong S, Jang D et al. (1998) Urine specimens from pregnant and nonpregnant women inhibitory to amplification of chlamydia trachomatis nucleic acid by PCR, ligase chain reaction, and transcription-mediated amplification: identification of urinary substances associated with inhibition and removal of inhibitory activity. J Clin Microbiol 36/11:3122–3126

    PubMed  CAS  Google Scholar 

  • Mamat U, Baumann M, Schmidt G, Brade H (1993) The genus-specific lipopolysaccharide epitope of chlamydia is assembled in C. psittaci and C. trachomatis by glycosyltransferases of low homology. Mol Microbiol 10/5:935–941

    Article  PubMed  CAS  Google Scholar 

  • Petersen EE, Obermann K, Graf von der Schulenburg J-M (1998) Health Care and Preventive measures via chlamydia screening. Geburtsh Frauenheilkd 58/8:408–414

    Article  Google Scholar 

  • Rödel J, Groh A, Hartmann M, Schmidt KH et al. (1999), Expression of interferon regulatory factors and indoleamine 2,3-dioxygenase in chlamydia trachomatis-infected synovial fibroblasts. Med Microbiol Immunol (Berl) 187/4:205–212

    Article  Google Scholar 

  • Rödel J, Groh A, Vogelsang H, Lehmann M, Hartmann M, Straube E (1998) Beta interferon is produced by chlamydia trachomatisinfected fibroblast-like synoviocytes and inhibits gamma interferon-induced HLA-DR expression. Infect Immun 66/9:4491–4495

    PubMed  Google Scholar 

  • Rödel J, Assefa S, Prochnau D, Woytas M, Hartmann M, Groh A, Straube E (2001) Interferon-beta induction by chlamydia pneumoniae in human smooth muscle cells. FEMS Immunol Med Microbiol 32/1:9–15

    Article  PubMed  Google Scholar 

  • Saikku P, Leinonen M, Mattila K et al. (1988) Serological evidence of an association of a novel chlamydia, TWAR, with chronic coronary heart disease and acute myocardial infarction. Lancet II(8618):983–986

    Article  Google Scholar 

  • Schachter J, Stephens RS, Timms P et al. (2001) Radical changes to chlamydial taxonomy are not necessary just yet. Int J Syst Evol Microbiol 51/1:251–253

    Google Scholar 

  • Scidmore-Carlson MA, Shaw El, Dooley CA, Fischer ER, Hackstadt T (1999) Identification and characterization of a chlamydia trachomatis early operon encoding four novel inclusion membrane proteins. Mol Microbiol 33/4:753–765

    Article  PubMed  CAS  Google Scholar 

  • Shafer MA, Pantell RH, Schachter J (1999) Is the routine pelvic examination needed with the advent of urine-based screening for sexually transmitted diseases?. Arch Pediatr Adolesc Med 153/2:119–125

    PubMed  CAS  Google Scholar 

  • Sieper J, Fendler C, Laitko S et al. (1999) No benefit of long-term ciprofloxacin treatment in patients with reactive arthritis and undifferentiated oligoarthritis: a three-month, multicenter, doubleblind, randomized, placebo-controlled study. Arthritis Rheum 42/7:1386–1396

    Article  PubMed  CAS  Google Scholar 

  • Wang SP, Grayston JT (1974) Human serology in chlamydia trachomatis infection with microimmunofluorescence. J Infect Dis 130/4:388–397

    Article  PubMed  CAS  Google Scholar 

  • Wyrick PB (1998) Cell biology of chlamydial infection: A journey in the host epithelial cell by the ultimate cellular microbiologist, in chlamydial infections. Proceedings of the 9th Internatinonal Symposium on Human Chlamydial Infection, Napa/CA, June 21-26, 1998

    Google Scholar 

  • Zeidler H, Mau W, Khan MA (1992) Undifferentiated spondyloarthropathies. Rheum Dis Clin North Am 18/1:187–202

    PubMed  CAS  Google Scholar 

  • Zhong G, Fan T, Liu L (1999) Chlamydia inhibits interferon gammainducible major histocompatibility complex class II expression by degradation of upstream stimulatory factor 1. J Exp Med 189/12:1931–1938

    Article  PubMed  CAS  Google Scholar 

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© 2004 Springer-Verlag Berlin Heidelberg

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Straube, E. (2004). Chlamydien. In: Adam, D., Doerr, H.W., Link, H., Lode, H. (eds) Die Infektiologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18577-9_26

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  • DOI: https://doi.org/10.1007/978-3-642-18577-9_26

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-00075-4

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