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Genetische Analyse bei Diabetes mellitus Typ 2 und MODY

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Zusammenfassung

Sowohl der Typ-1-als auch der Typ-2-Diabetes entstehen teilweise auf einer genetischen Grundlage; diese spielt jedoch für die Entstehung eines Typ-2-Diabetes eine sehr viel größere Rolle als für den Typ-1-Diabetes. Dies zeigt sich altersabhängig zum einen an der unterschiedlichen Prävalenz in verschiedenen ethnischen Gruppen, zum anderen an der familiären Häufung des Typ-2-Diabetes und der hohen Konkordanzrate von 35–90% bei monozygoten Zwillingen (▸ s. Kap. 1).

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Pfeiffer, A.F.H., Möhlig, M. (2004). Genetische Analyse bei Diabetes mellitus Typ 2 und MODY. In: Waldhäusl, W.K., Gries, F.A., Scherbaum, W.A. (eds) Diabetes in der Praxis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18571-7_5

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  • DOI: https://doi.org/10.1007/978-3-642-18571-7_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-62166-6

  • Online ISBN: 978-3-642-18571-7

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