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Interactions Between the Renin-Angiotensin and the Kallikrein-Kinin System

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Book cover Angiotensin Vol. II

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 163 / 2))

Abstract

Angiotensin-I-converting enzyme (ACE) has turned out to be a central target molecule in the successful treatment of many important cardiovascular diseases. The value of ACE inhibitors as therapeutic options has grown with every year over the past 2 decades, but our knowledge regarding the underlying mechanisms also increased. Today it seems that multiple interactions into the renin-angiotensin (RAS) and the kallikrein-kinin (KKS) system exist. This chapter summarizes what is currently known about the se interactions between RAS and KKS, with a specific focus on two target organs: the endothelium and the heart

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  1. Disease Group Cardiovascular, Aventis Pharma Industriepark Hochst, Building H 825, 65926, Frank furt, Germany

    P. Wohlfart & G. Wiemer

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  1. P. Wohlfart
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  2. G. Wiemer
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Wohlfart, P., Wiemer, G. (2004). Interactions Between the Renin-Angiotensin and the Kallikrein-Kinin System. In: Angiotensin Vol. II. Handbook of Experimental Pharmacology, vol 163 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18497-0_16

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  • DOI: https://doi.org/10.1007/978-3-642-18497-0_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-40641-9

  • Online ISBN: 978-3-642-18497-0

  • eBook Packages: Springer Book Archive

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