Reversible Transition of Photonic DNA Automaton Using Hairpin-DNA Responding to a Single Kind of Photonic Signal

  • Hiroto Sakai
  • Yusuke Ogura
  • Jun Tanida
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 6518)


In this paper, we report a scheme for reversible state-transition of the automaton responding to a single kind of a photonic signal. The state is encoded into the conformation of hairpin-DNAs tethered with azobenzene, which is responsive to visible and UV light irradiation. The reversible behavior is realized by carrying out a sequence of conformation-change of the hairpin-DNA in a stepwise manner. Experimental results demonstrate that the state can be changed reversibly according to photonic signals.


Light Irradiation Visible Light Irradiation Reversible Transition Spatial Light Modulator Photonic Signal 
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  1. 1.
    Benenson, Y., Paz-Elizur, T., Adar, R., Keinan, E., Livneh, Z., Shapiro, E.: Programmable and autonomous computing machine made of biomolecules. Nature 414, 430–434 (2001)CrossRefGoogle Scholar
  2. 2.
    Benenson, Y., Gil, B., Ben-Dor, U., Adar, R., Shapiro, E.: An autonomous molecular computer for logical control of gene expression. Nature 429, 1–6 (2004)CrossRefGoogle Scholar
  3. 3.
    Sakai, H., Ogura, Y., Tanida, J.: Positional state representation and its transition control for photonic DNA automaton. In: Deaton, R., Suyama, A. (eds.) DNA 15. LNCS, vol. 5877, pp. 126–136. Springer, Heidelberg (2009)CrossRefGoogle Scholar
  4. 4.
    Sakai, H., Ogura, Y., Tanida, J.: Implementation of a Nanoscale Automaton Using DNA Conformation Controlled by Optical Signals. Japanese Journal of Applied Physics 48, 09LA01 (2009)Google Scholar
  5. 5.
    Asanuma, H., Liang, X., Nishioka, H., Matsunaga, D., Liu, M., Komiyama, M.: Synthesis of azobenzene-tethered DNA for reversible photo-regulation of DNA functions: hybridization and transcription. Nature Protocols 2, 203–213 (2007)CrossRefGoogle Scholar
  6. 6.

Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Hiroto Sakai
    • 1
  • Yusuke Ogura
    • 1
  • Jun Tanida
    • 1
  1. 1.Department of Information and Physical Sciences, Graduate School of Information Science and TechnologyOsaka UniversitySuita, OsakaJapan

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