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Microsystems and Nanotechnology pp 759–818Cite as

Biochip

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Abstract

In this chapter, both microarray biochip and microfluidic biochip have been introduced. The background, fabrication technology, and detection technology of the microarray chips and microfluidic chips are presented. This chapter emphasizes microfluidic biochips (including sample pretreatment chips, polymerase chain reaction (PCR) chip, capillary electrophoresis (CE) chips, chromatography chips, hybridization chips, immunoassay chips, micro total analytical system) and their technologies. Many different approaches or methods are discussed here, including their advantages and disadvantages. Some of the microfluidic biochips, such as crossflow filtration chip for blood cells separation, porous silicon chip for DNA purification, chamber stationary PCR chip, glass/PDMS/glass sandwich CE chip, and so on, are designed and fabricated in the State Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing, China.

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Authors and Affiliations

  1. State Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing, China

    Dafu Cui

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  1. Dafu Cui
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  1. Department of Precision Instruments & Mechanology, Tsinghua University, Beijing, 100084, China

    Zhaoying Zhou

  2. Center for Nanostructure Characterization and Fabrication (CNCF), Georgia Institute of Technology, Atlanta, GA, 30332-0245, USA

    Liwei Lin

  3. Department of Mechanical Engineering, University of California at Berkeley, Berkeley, CA, 94720-1740, USA

    Zhonglin Wang

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© 2012 Tsinghua University Press, Beijing and Springer-Verlag Berlin Heidelberg

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Cui, D. (2012). Biochip. In: Zhou, Z., Wang, Z., Lin, L. (eds) Microsystems and Nanotechnology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18293-8_20

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