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Tumoral Abdomen

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Learning Pediatric Imaging

Part of the book series: Learning Imaging ((LEARN))

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Abstract

Neuroblastoma (NB) is the most common solid, extracranial tumor in infants and children. NB are of neural crest origin, and most cases arise in the adrenal medulla. Less often, NB may arise in other extra-adrenal sites along the sympathetic chain.

The median age at diagnosis is 22 months, and NB may occur in newborns. The clinical presentation depends on the site of the primary lesion or location of its metastatic spread. The vast majority of NB secrete catecholamine. Vasoactive intestinal peptide (VIP) may be secreted by the tumor and may result in watery diarrhea, hypokalemia, and acidosis. Stage, age at diagnosis, histology, and genetics (MYCN oncogene) are the most significant and clinically relevant prognostic factors.

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Authors and Affiliations

  1. Radiology Department Pediatric Radiology Unit, Hospital Materno-Infantil del C.H.U. Carlos Haya, Arroyo de los Angeles, 29011, Málaga, Spain

    María I. Martínez León

  2. Health Science Center, University of Texas, Elmscourt, 78230, San Antonio, TX, USA

    Juan E. Gutiérrez

  3. Radiology Department Pediatric Radiology Unit. Chief, Hospital Materno-Infantil del C.H.U. Carlos Haya, Arroyo de los Angeles, 29011, Málaga, Spain

    Luisa Ceres Ruiz

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León, M.I.M., Gutiérrez, J.E., Ruiz, L.C. (2011). Tumoral Abdomen. In: Learning Pediatric Imaging. Learning Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-16892-5_6

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