Footmarks of INIM
- 390 Downloads
“See no evil, hear no evil and do no evil” is the appealing title of a review of immune-privileged organs (Niederkorn 2006). The statement perfectly fits the ovary, which faces regular damage from follicular atresia and cyclic follicle rupture as well as garbage disposal of the CL. The ovary hears and responds to danger signals by inflammatory processes (Espey 1994), yet it does no evil. By coordinated repair processes, the function of the ovary is perfectly restored.
KeywordsGranulosa Cell Complement System Danger Signal Antral Follicle Preantral Follicle
- Brylla E, Aust G, Geyer M, Uckermann O, Löffler S, Spanel-Borowski K (2005) Coexpression of preprotachykinin A and B transcripts in the bovine corpus luteum and evidence for functional neurokinin receptor activity in luteal endothelial cells and ovarian macrophages. Regul Pept 125:125–133CrossRefPubMedGoogle Scholar
- Jakob W, Jentzsch KD, Mauersberger B, Oehme P (1977) Demonstration of angiogenesis-activity in the corpus luteum of cattle. Exp Pathol (Jena) 13:231–236Google Scholar
- Löffler S, Schulz A, Brylla E, Nieber K, Spanel-Borowski K (2004a) Transcripts of neurokinin B and neurokinin 3 receptor in superovulated rat ovaries and increased number of corpora lutea as a non-specific effect of intraperitoneal agonist application. Regul Pept 122:131–137CrossRefPubMedGoogle Scholar
- Spanel-Borowski K, Vaughan LY, Johnson LY, Reiter RJ (1983b) Increase of intra-ovarian oocyte release in PMSG-primed immature rats and its inhibition by arginine vasotocin. Biomed Res 4:71–82Google Scholar