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Future Trends in Sports Traumatology: The Puzzling Human Joint

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Sports Injuries

Abstract

Epidemiologic data demonstrate increase in awareness of the benefits of physical activity crossing age and gender, thus increasing the number musculoskeletal injuries.

Joint injuries pose a remarkable challenge due to the highly specialized hyalin cartilage that in the face of injury has no regenerative capability.

Chondrocytes extracted from their natural environment, invariably lose their genetic phenotype by way of dedifferentiation. Various technologies combining adult stem cells enhanced by biomaterials, in-vitro autologous chondrocytes culture on bioabsorbable scaffolds, and the use of growth factors and genetic selection have all resulted in hyaline-like tissue.

Limited clinical trials are conducted with fresh allogeneic cartilage cells. Preclinical studies are available where xenogeneic neonatal porcine cells are used for regenerative purposes. It is difficult to predict the technology and the timing of the next breakthrough; it is encouraging to observe the scientific broadmindedness.

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Author information

Authors and Affiliations

  1. Division of Orthopaedic Surgery, Service for Sports Traumatology, Rambam Health Care Campus, Haifa, 31096, Israel

    Gabriel Nierenberg

  2. Division of Orthopaedic Surgery, Rambam Health Care Campus, Haifa, 31096, Israel

    Michael Soudry

  3. Department of Cell Biology, Rappaport School of Medicine, Technion–Israel Institution of Technology, Efron, Haifa, 31096, Israel

    Gila Maor

Authors
  1. Gabriel Nierenberg
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  2. Michael Soudry
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  3. Gila Maor
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Corresponding author

Correspondence to Gabriel Nierenberg .

Editor information

Editors and Affiliations

  1. Fac. Medicine, Dept. Orthopedics & Traumatology, Hacettepe University, Hasyrcylar Caddesi, Ankara, 94110, Turkey

    Mahmut Nedim Doral

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Nierenberg, G., Soudry, M., Maor, G. (2012). Future Trends in Sports Traumatology: The Puzzling Human Joint. In: Doral, M. (eds) Sports Injuries. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-15630-4_156

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  • DOI: https://doi.org/10.1007/978-3-642-15630-4_156

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-15629-8

  • Online ISBN: 978-3-642-15630-4

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