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Nebennieren

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Praxis der Viszeralchirurgie

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Zusammenfassung

Die Nebennieren umfassen 2 anatomisch und funktionell unterscheidbare Organe: die Nebennierenrinde und das Nebennierenmark. Beide spielen eine zentrale Rolle in der Stressbewältigung und sind regulativ miteinander verknüpft. Unterfunktionen der Nebennierenrinde können primär (z. B. durch Organzerstörung) oder sekundär durch den Ausfall regulativer Hormone (ACTH, Renin) bedingt sein. Ein Ausfall des Nebennierenmarks ist von geringer klinischer Bedeutung. Überfunktionssyndrome der Nebenniere (Cushing-Syndrom, primärer Hyperaldosteronismus, Phäochromozytom) sind oft die Folge monoklonaler adrenaler Tumoren, die in ihrer Mehrzahl benigne sind und zur Suppression der Funktion der intakten kontralateralen und der paraadenomatösen Nebenniere führen können. Sie können auch sekundär durch eine gesteigerte Stimulation der Nebenniere entstehen (z. B. ACTH-abhängiges Cushing-Syndrom). Adrenale Enzymdefekte sind meist durch eine Kombination von Unterfunktion und Überfunktion als Folge der Anhäufung von Steroidhormonvorstufen gekennzeichnet.

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Author notes

  1. B. Allolio

    Present address: Medizinische Klinik und Poliklinik I, Universitätsklinikum Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Deutschland

  2. C. Nies

    Present address: Allgemein-, Thorax- und Gefässchirurgie, Marienhospital Osnabrück GmbH, Bischofstraße 1, 49074 , Osnabrück, Deutschland

  3. R. Moll

    Present address: Institut für Pathologie, Universitätsklinikum Marburg, Baldingerstr., 35043, Marburg, Deutschland

  4. K.J. Klose

    Present address: Med. Zentrum für Radiologie, Universitätsklinikum Marburg, Baldingerstr., 35043, Marburg, Deutschland

  5. P.H. Kann

    Present address: Visceral-, Thorax- und Gefäßchirurgie, Universitätsklinikum Marburg, Baldingerstr., 35043, Marburg, Deutschland

  6. A. Pfestroff

    Present address: Institut für Nuklearmedizin, Universitätsklinikum Marburg, Baldingerstr., 35043 , Marburg, Deutschland

  7. J. Waldmann & D.K. Bartsch

    Present address: Visceral-, Thorax- und Gefäßchirurgie, Universitätsklinikum Marburg, Baldingerstr., 35043, Marburg, Deutschland

  8. H. Lehnert

    Present address: Campus Lübeck, Medizinische Klinik I, Universitätsklinikum Schleswig-Holstein, Ratzeburger Allee 160, 23538 , Lübeck, Deutschland

  9. H. Dralle

    Present address: Klinikum Kröllwitz, Martin-Luther-Universität Halle-Wittenberg, Ernst-Grube-Str. 40, 06120 , Halle, Deutschland

  10. O. Gimm

    Present address: Dept. of Clinical and Experimental Medicine, Linköping University, 58185 , Linköping, Deutschland

  11. A. Machens

    Present address: , Beatestraße 3c, 13505 , Berlin, Deutschland

  12. T.J. Musholt

    Present address: Allgemein- und Visceralchirurgie, Universität Mainz, Langenbeckstr. 1, 55101 , Mainz, Deutschland

  13. M. Slawik & M. Reincke

    Present address: Klinikum Innenstadt, Medizinische Klinik, Universitätsklinikum München, Ziemssenstr. 1, 80336 , München, Deutschland

  14. M. Walz

    Present address: Klinik für Chirurgie, Kliniken Essen-Mitte, Henricistr. 92, 45136 , Essen, Deutschland

  15. P.J. Barth Prof. Dr. med.

    Present address: Institut für Pathologie, Universitätsklinikum, Domagkstr. 17, 48149, Münster, Deutschland

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    1. B. Allolio
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    17. P.J. Barth Prof. Dr. med.
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    Editor information

    Editors and Affiliations

    1. Universitätsklinikum Freiburg, Hugstetter Str. 49, Freiburg, 79106, Germany

      Jörg Rüdiger Siewert

    2. Med. Zentrum für Operative Medizin I, Klinik für Allgemeinchirurgie, Univ.Klinikum Marburg, Baldingerstr., Marburg, 35033, Germany

      Matthias Rothmund

    3. Universitätsklinikum, Chirurgische Klinik und Poliklinik, RWTH Aachen, Pauwelsstr. 30, Aachen, 52074, Germany

      Volker Schumpelick

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    Allolio, B. et al. (2013). Nebennieren. In: Siewert, J., Rothmund, M., Schumpelick, V. (eds) Praxis der Viszeralchirurgie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-14285-7_4

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    • DOI: https://doi.org/10.1007/978-3-642-14285-7_4

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