Skip to main content

Morphologische Grundlagen

  • Chapter
  • 2581 Accesses

Zusamenfassung

In der interdisziplinären Versorgung von Patientinnen mit Mammakarzinom ist es die Aufgabe des Pathologen, jene Parameter zu begutachten, die entscheidend sind für die individuell angemessene Therapie. Im Folgenden sollen daher diese Parameter näher erläutert werden.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   29.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD   79.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Albert US, Altland H, Duda V, et al. (2008) Stufe-3-Leitlinie Brustkrebsfrüherkennung in Deutschland. Zuckschwerdt, München

    Google Scholar 

  • Amendoeira I, Apostolikas N, Bellocq JP, et al. (2006) Quality assurance guidelines for pathology: Open biopsy and resection specimens. In: Perry N, Broeders M, de Wolf C, Toernberg S, Holland R, von Karsa L (eds) European guidelines for quality assurance in breast cancer screening and diagnosis, pp 256–311. Office for Official Publications of the European Communities: Luxembourg

    Google Scholar 

  • Beckmann MW, Blohmer JU, Costa SD, et al. (2009) Zürich Konsens: Stellungnahme deutscher Experten zum St. Gallen-Votum am 15. März 2009. Geburtshilfe Frauenheilkd 69: 377–383

    Article  Google Scholar 

  • Carlson RW, Moench SJ, Hammond ME, et al. (2006) HER2 testing in breast cancer: NCCN Task Force report and recommendations. J Natl Compr Canc Netw 4Suppl 3: S1–22

    Google Scholar 

  • Eheman CR, Shaw KM, Ryerson AB, et al. (2009) The changing incidence of in situ and invasive ductal and lobular breast carcinomas: United States, 1999–2004. Cancer Epidemiol Biomarkers Prev 18: 1763–1769

    Article  PubMed  Google Scholar 

  • Ellis IO, Galea M, Broughton N, et al. (1992) Pathological prognostic factors in breast cancer. II. Histological type. Relationship with survival in a large study with long-term follow-up. Histopathology 20: 479–489

    Article  CAS  PubMed  Google Scholar 

  • Elston CW, Ellis IO (1991) Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology 19: 403–410

    Article  CAS  PubMed  Google Scholar 

  • Faverly DR, Burgers L, Bult P, Holland R (1994) Three dimensional imaging of mammary ductal carcinoma in situ: clinical implications. Semin Diagn Pathol 11: 193–198

    CAS  PubMed  Google Scholar 

  • Fisher ER, Anderson S, Redmond C, Fisher B (1993) Pathologic findings from the National Surgical Adjuvant Breast Project protocol B-06.10-year pathologic and clinical prognostic discriminants. Cancer 71: 2507–2514

    Article  CAS  PubMed  Google Scholar 

  • Goldhirsch A, Ingle JN, Gelber RD, et al. (2009) Thresholds for therapies: highlights of the St Gallen International Expert Consensus on the primary therapy of early breast cancer 2009. Ann Oncol 20: 1319–1329

    Article  CAS  PubMed  Google Scholar 

  • Gralow JR, Burstein HJ, Wood W, et al. (2008) Preoperative therapy in invasive breast cancer: pathologic assessment and systemic therapy issues in operable disease. J Clin Oncol 26: 814–819

    Article  PubMed  Google Scholar 

  • Harvey JM, Clark GM, Osborne CK, Allred DC (1999) Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer. J Clin Oncol 17: 1474–1481

    CAS  PubMed  Google Scholar 

  • Huang EH, Strom EA, Perkins GH, et al. (2006) Comparison of risk of local-regional recurrence after mastectomy or breast conservation therapy for patients treated with neoadjuvant chemotherapy and radiation stratified according to a prognostic index score. Int J Radiat Oncol Biol Phys 66: 352–357

    Article  PubMed  Google Scholar 

  • Kreienberg R, Kopp I, Albert US, et al. (2008) Interdisziplinäre S3-Leitliniefür die Diagnostik, Therapie und Nachsorge des Mammakarzinoms. Zuckschwerdt, München

    Google Scholar 

  • Kuehn T, Bembenek A, Decker T, et al. (2005) A concept for the clinical implementation of sentinel lymph node biopsy in patients with breast carcinoma with special regard to quality assurance. Cancer 103: 451–461

    Article  PubMed  Google Scholar 

  • Lyman GH, Giuliano AE, Somerfield MR, et al. (2005) American Society of Clinical Oncology guideline recommendations for sentinel lymph node biopsy in early-stage breast cancer. J Clin Oncol 23: 7703–7720

    Article  PubMed  Google Scholar 

  • Mazouni C, Peintinger F, Wan-Kau S, et al. (2007) Residual ductal carcinoma in situ in patients with complete eradication of invasive breast cancer after neoadjuvant chemotherapy does not adversely affect patient outcome. J Clin Oncol 25: 2650–2655

    Article  CAS  PubMed  Google Scholar 

  • Perou CM, Sorlie T, Eisen MB, et al. (2000) Molecular portraits of human breast tumours. Nature 406: 747–752

    Article  CAS  PubMed  Google Scholar 

  • Remmele W, Stegner HE (1987) (Recommendation for uniform definition of an immunoreactive score (IRS) for immunohistochemical estrogen receptor detection (ER-ICA) in breast cancer tissue). Pathologe 8: 138–140

    CAS  PubMed  Google Scholar 

  • Rosen PP, Groshen S, Kinne DW, Norton L (1993) Factors influencing prognosis in node-negative breast carcinoma: analysis of 767 T1N0M0/T2N0M0 patients with long-term follow-up. J Clin Oncol 11: 2090–2100

    CAS  PubMed  Google Scholar 

  • Ross JS, Hatzis C, Symmans WF, et al. (2008) Commercialized multigene predictors of clinical outcome for breast cancer. Oncologist 13: 477–493

    Article  PubMed  Google Scholar 

  • Schnitt SJ, Abner A, Gelman R, Connolly JL, Recht A, Duda RB, Eberlein TJ, Mayzel K, Silver B, Harris JR (1994) The relationship between microscopic margins of resection and the risk of local recurrence in patients with breast cancer treated with breast-conserving surgery and radiation therapy. Cancer 74: 1746–1751

    Article  CAS  PubMed  Google Scholar 

  • Sorlie T, Perou CM, Tibshirani R, et al. (2001) Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 98: 10869–10874

    Article  CAS  PubMed  Google Scholar 

  • Symmans WF, Peintinger F, Hatzis C, et al. (2007) Measurement of residual breast cancer burden to predict survival after neoadjuvant chemotherapy. J Clin Oncol 25: 4414–4422

    Article  PubMed  Google Scholar 

  • Wolff AC, Hammond ME, Schwartz JN, et al. (2007) American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. J Clin Oncol 25: 118–145

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer-Verlag Berlin Heidelberg New York

About this chapter

Cite this chapter

Lebeau, A., Mitze, M. (2010). Morphologische Grundlagen. In: Mammakarzinom Interdisziplinär. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-12681-9_9

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-12681-9_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-12680-2

  • Online ISBN: 978-3-642-12681-9

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics