Zusamenfassung
In der interdisziplinären Versorgung von Patientinnen mit Mammakarzinom ist es die Aufgabe des Pathologen, jene Parameter zu begutachten, die entscheidend sind für die individuell angemessene Therapie. Im Folgenden sollen daher diese Parameter näher erläutert werden.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
Literatur
Albert US, Altland H, Duda V, et al. (2008) Stufe-3-Leitlinie Brustkrebsfrüherkennung in Deutschland. Zuckschwerdt, München
Amendoeira I, Apostolikas N, Bellocq JP, et al. (2006) Quality assurance guidelines for pathology: Open biopsy and resection specimens. In: Perry N, Broeders M, de Wolf C, Toernberg S, Holland R, von Karsa L (eds) European guidelines for quality assurance in breast cancer screening and diagnosis, pp 256–311. Office for Official Publications of the European Communities: Luxembourg
Beckmann MW, Blohmer JU, Costa SD, et al. (2009) Zürich Konsens: Stellungnahme deutscher Experten zum St. Gallen-Votum am 15. März 2009. Geburtshilfe Frauenheilkd 69: 377–383
Carlson RW, Moench SJ, Hammond ME, et al. (2006) HER2 testing in breast cancer: NCCN Task Force report and recommendations. J Natl Compr Canc Netw 4Suppl 3: S1–22
Eheman CR, Shaw KM, Ryerson AB, et al. (2009) The changing incidence of in situ and invasive ductal and lobular breast carcinomas: United States, 1999–2004. Cancer Epidemiol Biomarkers Prev 18: 1763–1769
Ellis IO, Galea M, Broughton N, et al. (1992) Pathological prognostic factors in breast cancer. II. Histological type. Relationship with survival in a large study with long-term follow-up. Histopathology 20: 479–489
Elston CW, Ellis IO (1991) Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology 19: 403–410
Faverly DR, Burgers L, Bult P, Holland R (1994) Three dimensional imaging of mammary ductal carcinoma in situ: clinical implications. Semin Diagn Pathol 11: 193–198
Fisher ER, Anderson S, Redmond C, Fisher B (1993) Pathologic findings from the National Surgical Adjuvant Breast Project protocol B-06.10-year pathologic and clinical prognostic discriminants. Cancer 71: 2507–2514
Goldhirsch A, Ingle JN, Gelber RD, et al. (2009) Thresholds for therapies: highlights of the St Gallen International Expert Consensus on the primary therapy of early breast cancer 2009. Ann Oncol 20: 1319–1329
Gralow JR, Burstein HJ, Wood W, et al. (2008) Preoperative therapy in invasive breast cancer: pathologic assessment and systemic therapy issues in operable disease. J Clin Oncol 26: 814–819
Harvey JM, Clark GM, Osborne CK, Allred DC (1999) Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer. J Clin Oncol 17: 1474–1481
Huang EH, Strom EA, Perkins GH, et al. (2006) Comparison of risk of local-regional recurrence after mastectomy or breast conservation therapy for patients treated with neoadjuvant chemotherapy and radiation stratified according to a prognostic index score. Int J Radiat Oncol Biol Phys 66: 352–357
Kreienberg R, Kopp I, Albert US, et al. (2008) Interdisziplinäre S3-Leitliniefür die Diagnostik, Therapie und Nachsorge des Mammakarzinoms. Zuckschwerdt, München
Kuehn T, Bembenek A, Decker T, et al. (2005) A concept for the clinical implementation of sentinel lymph node biopsy in patients with breast carcinoma with special regard to quality assurance. Cancer 103: 451–461
Lyman GH, Giuliano AE, Somerfield MR, et al. (2005) American Society of Clinical Oncology guideline recommendations for sentinel lymph node biopsy in early-stage breast cancer. J Clin Oncol 23: 7703–7720
Mazouni C, Peintinger F, Wan-Kau S, et al. (2007) Residual ductal carcinoma in situ in patients with complete eradication of invasive breast cancer after neoadjuvant chemotherapy does not adversely affect patient outcome. J Clin Oncol 25: 2650–2655
Perou CM, Sorlie T, Eisen MB, et al. (2000) Molecular portraits of human breast tumours. Nature 406: 747–752
Remmele W, Stegner HE (1987) (Recommendation for uniform definition of an immunoreactive score (IRS) for immunohistochemical estrogen receptor detection (ER-ICA) in breast cancer tissue). Pathologe 8: 138–140
Rosen PP, Groshen S, Kinne DW, Norton L (1993) Factors influencing prognosis in node-negative breast carcinoma: analysis of 767 T1N0M0/T2N0M0 patients with long-term follow-up. J Clin Oncol 11: 2090–2100
Ross JS, Hatzis C, Symmans WF, et al. (2008) Commercialized multigene predictors of clinical outcome for breast cancer. Oncologist 13: 477–493
Schnitt SJ, Abner A, Gelman R, Connolly JL, Recht A, Duda RB, Eberlein TJ, Mayzel K, Silver B, Harris JR (1994) The relationship between microscopic margins of resection and the risk of local recurrence in patients with breast cancer treated with breast-conserving surgery and radiation therapy. Cancer 74: 1746–1751
Sorlie T, Perou CM, Tibshirani R, et al. (2001) Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 98: 10869–10874
Symmans WF, Peintinger F, Hatzis C, et al. (2007) Measurement of residual breast cancer burden to predict survival after neoadjuvant chemotherapy. J Clin Oncol 25: 4414–4422
Wolff AC, Hammond ME, Schwartz JN, et al. (2007) American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. J Clin Oncol 25: 118–145
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2010 Springer-Verlag Berlin Heidelberg New York
About this chapter
Cite this chapter
Lebeau, A., Mitze, M. (2010). Morphologische Grundlagen. In: Mammakarzinom Interdisziplinär. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-12681-9_9
Download citation
DOI: https://doi.org/10.1007/978-3-642-12681-9_9
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-12680-2
Online ISBN: 978-3-642-12681-9
eBook Packages: Medicine (German Language)