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Extracellular Nucleic Acids of the Marine Phototrophic Bacterium Rhodovulum sulfidophilum and Related Bacteria: Physiology and Biotechnology

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Book cover Extracellular Nucleic Acids

Part of the book series: Nucleic Acids and Molecular Biology ((NUCLEIC,volume 25))

Abstract

Extracellular nucleic acids of high molecular weight are present ubiquitously throughout the environment, such as seawater and soil. These nucleic acids were formerly thought to be derived from cells by cell death, but recent studies have shown that they are at least partly derived from the active release of nucleic acids from some bacterial cells. Marine phototrophic bacteria, Rhodovulum sulfidophilum and Rhodovulum sp. strain PS88, produce extracellular nucleic acids and form flocs, i.e., structured communities of cells. This chapter describes highly efficient extracellular nucleic acid production of Rhodovulum sp. strain PS88 and the physiological relationships between extracellular nucleic acids and flocculation in Rdv. sulfidophilum. The structures of extracellular soluble DNA and RNA of Rdv. sulfidophilum are also described. Moreover, proposals for application of these properties to industrial productions of nucleotides and RNA drugs are discussed.

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Acknowledgements

I thank Akira Hiraishi and Hiromichi Suzuki for valuable advice in preparing the manuscript. The work performed in Kikuchi’s laboratory was supported in part by a grant for scientific research from the Ministry of Education, Culture, Sports, Science and Technology of Japan.

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Authors and Affiliations

  1. Department of Environmental and Life Sciences, Toyohashi University of Technology, 1-1 Hibarigaoka, Tempaku-cho, 441-8580, Toyohashi, Japan

    Yo Kikuchi

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  1. Yo Kikuchi
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Correspondence to Yo Kikuchi .

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Editors and Affiliations

  1. , Dept. of Environmental and Life Sciences, Toyohashi University of Technology, Toyohashi-city, 441-8580, Japan

    Yo Kikuchi

  2. Fundamental Medicine, Institute of Chemical Biology and, Lavrentjeva Prospect 8, Novosibirsk, 630090, Russian Federation

    Elena Y. Rykova

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Kikuchi, Y. (2010). Extracellular Nucleic Acids of the Marine Phototrophic Bacterium Rhodovulum sulfidophilum and Related Bacteria: Physiology and Biotechnology. In: Kikuchi, Y., Rykova, E. (eds) Extracellular Nucleic Acids. Nucleic Acids and Molecular Biology, vol 25. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-12617-8_5

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