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Mechanisms and Evolution of Dorsal–Ventral Patterning

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Evolutionary Biology – Concepts, Molecular and Morphological Evolution

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Abstract

In the last two decades, a great progress has been made with the discovery and understanding of conserved signaling pathways, in particular those involved in embryonic dorsal–ventral patterning and the organization of the nervous system. Remarkably, the spatial distribution of these signal molecules appears conserved across a large group of animals that have centralized nervous systems. Despite these achievements, there are still many unanswered questions on how the nervous system organization evolves and responds to variations in organism size. In this review, we discuss the progression of the field from early observations made more than a century ago and introduce future challenges regarding the problem of scaling of the nervous system during evolution.

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Authors and Affiliations

  1. Department of Biology, Case Western Reserve University, 10900 Euclid Ave, Cleveland, OH, 447080, USA

    Claudia Mieko Mizutani & Rui Sousa-Neves

  2. Department of Genetics, Case Western Reserve University, 10900 Euclid Ave, Cleveland, OH, 447080, USA

    Claudia Mieko Mizutani

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  1. Claudia Mieko Mizutani
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  2. Rui Sousa-Neves
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Correspondence to Claudia Mieko Mizutani .

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  1. CNRS UMR 6632, Labo. Evolution Biologique et, Université d'Aix-Marseille, place Victor Hugo 3, Marseille CX 03, 13331, France

    Pierre Pontarotti

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Mizutani, C.M., Sousa-Neves, R. (2010). Mechanisms and Evolution of Dorsal–Ventral Patterning. In: Pontarotti, P. (eds) Evolutionary Biology – Concepts, Molecular and Morphological Evolution. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-12340-5_10

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