Skip to main content

Unsupervised Change-Detection in Retinal Images by a Multiple-Classifier Approach

  • Conference paper
Multiple Classifier Systems (MCS 2010)

Part of the book series: Lecture Notes in Computer Science ((LNTCS,volume 5997))

Included in the following conference series:

Abstract

The aim of this work is the development of an unsupervised method for the detection of the changes that occurred in multitemporal digital images of the fundus of the human retina, in terms of white and red spots. The images are acquired from the same patient at different times by a fundus camera. The proposed method is an unsupervised multiple classifier approach, based on a minimum-error thresholding technique. This technique is applied to separate the “change” and the “no-change” areas in a suitably defined difference image. In particular, the thresholding approach is applied to selected sub-images: the outputs of the different windows are combined with a majority vote approach, in order to cope with local illumination differences. A quantitative assessment of the change detection performances suggests that the proposed method is able to provide accurate change maps, although possibly affected by misregistration errors or calibration/acquisition artifacts. The comparison between the results obtained using the implemented multiple classifier approach and a standard one points out that the proposed algorithm provides an accurate detection of the temporal changes.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Fritzsche, K.H.: Computer vision algorithms for retinal vessel detection and width change detection. Ph.D. dissertation, Rensselaer Polytechnic Inst. Try, New York (2004)

    Google Scholar 

  2. Akita, K., Kuga, H.: A computer method of understanding ocular fundus images. J. Pattern recognition 15, 431–443 (1982)

    Article  Google Scholar 

  3. Berger, J.W., Shin, D.S.: Computer vision enabled augmented reality fundus biomicroscopy. J. Ophthalmology 106 (1999)

    Google Scholar 

  4. Cree, M.J., Olson, J.A., McHardy, K.C., Sharp, P.F., Forrester, J.V.: A fully automated comparative microaneurysm digital detection system. J. Eye 11, 622–628 (1997)

    Google Scholar 

  5. Lalibert, F., Gagnon, L., Sheng, Y.: Registration, fusion of retinal images - an evaluation study. IEEE Transactions on Medical Imaging 22, 661–673 (2003)

    Article  Google Scholar 

  6. Usher, D., Dumskyj, M., Himaga, M., Williamson, T.H., Nussey, S., Boyce, J.: Automated detection of diabetic retinopathy in digital retinal images: a tool for diabetic retinopathy screening. J. Diabetic Medicine 21, 84–90 (2003)

    Article  Google Scholar 

  7. Hipwell, J.H., Strachan, F., Olson, J.A., McHardy, K.C., Sharp, P.F., Forrester, J.V.: Automated detection of microaneurysms in digital red-free photographs: a diabetic retinopathy screening tool. J. Diabetic Medicine 17, 588–594 (2000)

    Article  Google Scholar 

  8. Walter, T., Klein, J.C., Massin, P., Erginary, A.: A contribution of image processing to the diagnosis of diabetic retinopathy - detection of exudates in color fundus images of the human retina. IEEE Transactions on Medical Imaging 21, 1236–1243 (2002)

    Article  Google Scholar 

  9. Kittler, J., Illingworth, J.: Minimum error thresholding. J. Pattern Recognition 19, 41–47 (1986)

    Article  Google Scholar 

  10. Kuncheva, L.I.: Combining pattern classifiers: Method and algorithms. Wiley Interscience, New Jersey (2004)

    Book  Google Scholar 

  11. Troglio, G., Nappo, A., Benediktsson, J.A., Moser, G., Serpico, S.B., Stefansson, E.: Automatic Change Detection of Retinal Images. In: Proceedings of the IUPESM Medical Physics and Biomedical Engineering - World Congress (2009)

    Google Scholar 

  12. Gonzalez, R.C., Woods, R.E.: Digital Image Processing. Prentice Hall Inc., Englewood Cliffs (2001)

    Google Scholar 

  13. Sinthanayothin, C., Boyce, J.F., Cook, H.L., Williamson, T.H.: Automated localisation of the optic disc, fovea, and retinal blood vessels from digital color fundus images. British Journal of Ophthalmology 83, 902–910 (1999)

    Article  Google Scholar 

  14. Narasimha-Iyer, H., Can, A., Roysam, B., Stewart, C.V.: Robust detection and classification of longitudinal changes in color retinal fundus images for monitoring diabetic retinopathy. IEEE Transactions on Biomedical Engineering 53(6), 1084–1098 (2006)

    Article  Google Scholar 

  15. Chi, Z., Yan, H., Pham, T.: Fuzzy algorithms: with applications to image processing and pattern recognition. World Scientific Publishing, Singapore (1996)

    MATH  Google Scholar 

  16. Duda, R.O., Hart, P.E., Stork, D.G.: Pattern Classification. Wiley, New York (2001)

    MATH  Google Scholar 

  17. Sinthanayothin, C., Boyce, J.F., Williamson, T.H., Cook, H.L., Mensah, E., Lal, S., et al.: Automated detection of diabetic retinopathy on digital fundus images. J. Diabetic Medicine 19, 105–112 (2002)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Troglio, G., Alberti, M., Benediksson, J.A., Moser, G., Serpico, S.B., Stefánsson, E. (2010). Unsupervised Change-Detection in Retinal Images by a Multiple-Classifier Approach. In: El Gayar, N., Kittler, J., Roli, F. (eds) Multiple Classifier Systems. MCS 2010. Lecture Notes in Computer Science, vol 5997. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-12127-2_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-12127-2_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-12126-5

  • Online ISBN: 978-3-642-12127-2

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics