Nanocrystalline Silver: Novel Structure and Activity

  • Robert E. Burrell
  • Patricia Nadworny
Part of the IFMBE Proceedings book series (IFMBE, volume 27)


Silver, as Ag + , is a well known antimicrobial agent. Depending upon the delivery vehicle the single silver ion may be proinflammatory which could delay wound healing. Further, the Ag+ ion is chemically very active forming complexes with Cl and proteins which reduces its antimicrobial efficacy. The advent of nanostructured silver has solved the antimicrobial issues by controlling the release of silver and generating new silver species. These new species have introduced a host of unexpected benefits around wound healing. Of particular importance is the anti-inflammatory activity which dramatically improves healing.


Nanomedicine Antimicrobial Anti-inflammatory Nanosilver Wound healing 


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Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • Robert E. Burrell
    • 1
  • Patricia Nadworny
    • 2
  1. 1.Professor and Chair, Department of Biomedical Engineering, Faculties of Engineering and of Medicine & DentistryUniversity of Alberta 
  2. 2.Professor and Canada Research Chair in Nanostructured Biomaterials, Department of Chemical and Materials Engineering, Faculty of EngineeringUniversity of Alberta 

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