Advertisement

Malignant Mesothelioma

  • David A. WallerEmail author
  • Muhammad Javed
Chapter
  • 2.2k Downloads

Abstract

Video-assisted thoracic surgery (VATS) can be used at many points in the patient’s pathway through the course of the disease. VATS is the most reliable method of diagnosis and may be combined with mediastinoscopy to give the stage of disease. VATS pleurodesis is the most reliable method of effusion control when the lung re-expands and is the best method of achieving relief of dyspnoea due to lung entrapment by VATS decortication. Furthermore, the cytoreductive effect of this procedure may delay disease progression and prolong survival.

Keywords

Malignant Pleural Mesothelioma Malignant Mesothelioma Delay Disease Progression Pleural Empyema Talc Pleurodesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Cardillo G, Facciolo F, Carbone L, Regal M, Corzani F, Ricci A, Di Martino M, Martelli M (2002) Long-term follow-up of video-assisted talc pleurodesis in malignant recurrent pleural effusions. Eur J Cardiothorac Surg 21(2):302–305; discussion 305–6PubMedCrossRefGoogle Scholar
  2. 2.
    Fowkes L, Lau KK, Shah N, Black E (2009) A cervical approach to investigating pleural disease. Ann Thorac Surg 88(1):315–317PubMedCrossRefGoogle Scholar
  3. 3.
    Chamberlain MH, Fareed K, Nakas A, Martin-Ucar AE, Waller DA (2008) Video-assisted cervical thoracoscopy: a novel approach for diagnosis, staging and pleurodesis of malignant pleural mesothelioma. Eur J Cardiothorac Surg 34(1):200–203PubMedCrossRefGoogle Scholar
  4. 4.
    Stefani A, Natali P, Casali C, Morandi U (2006) Talc poudrage versus talc slurry in the treatment of malignant pleural effusion. A prospective comparative study. Eur J Cardiothorac Surg 30(6):827–832PubMedCrossRefGoogle Scholar
  5. 5.
    Gonzalez AV, Bezwada V, Beamis JF Jr, Villanueva AG (2010) Lung injury following thoracoscopic talc insufflation: experience of a single north American center. Chest 137(6):1375–1381, Epub 2010 Jan 22PubMedCrossRefGoogle Scholar
  6. 6.
    Ferrer J, Montes JF, Villarino MA, Light RW, García-Valero J (2002) Influence of particle size on extrapleural talc dissemination after talc slurry pleurodesis. Chest 122(3):1018–1027PubMedCrossRefGoogle Scholar
  7. 7.
    Waller DA, Morritt GN, Forty J (1995) Video-assisted thoracoscopic pleurectomy in the management of malignant pleural effusion. Chest 107(5):1454–1456PubMedCrossRefGoogle Scholar
  8. 8.
    Halstead JC, Lim E, Venkateswaran RM, Charman SC, Goddard M, Ritchie AJ (2005) Improved survival with VATS pleurectomy-decortication in advanced malignant mesothelioma. Eur J Surg Oncol 31(3):314–320PubMedCrossRefGoogle Scholar
  9. 9.
    Martin-Ucar AE, Edwards JG, Rengajaran A, Muller S, Waller DA (2001) Palliative surgical debulking in malignant mesothelioma. Predictors of survival and symptom control. Eur J Cardiothorac Surg 20(6):1117–1121PubMedCrossRefGoogle Scholar
  10. 10.
    Waller DA, Rengarajan A (2001) Thoracoscopic decortication: a role for video-assisted surgery in chronic postpneumonic pleural empyema. Ann Thorac Surg 71(6):1813–1816PubMedCrossRefGoogle Scholar
  11. 11.
    Nakas A, Martin Ucar AE, Edwards JG, Waller DA (2008) The role of video assisted thoracoscopic pleurectomy/decortication in the therapeutic management of malignant pleural mesothelioma. Eur J Cardiothorac Surg 33(1):83–88PubMedCrossRefGoogle Scholar
  12. 12.
    Srivastava V, Dunning J, Au J (2009) Does video-assisted thoracoscopic decortication in advanced malignant mesothelioma improve prognosis? Interact Cardiovasc Thorac Surg 8(4):454–456PubMedCrossRefGoogle Scholar
  13. 13.
    Efthymiou CA, Masudi T, Thorpe JA, Papagian­nopoulos K (2009) Malignant pleural effusion in the presence of trapped lung. Five-year experience of PleurX tunnelled catheters. Interact Cardiovasc Thorac Surg 9(6):961–964, Epub 2009 Jul 28PubMedCrossRefGoogle Scholar
  14. 14.
    Olden AM, Holloway R (2010) Treatment of malignant pleural effusion: pleuRx catheter or talc ­pleurodesis? A cost-effectiveness analysis. J Palliat Med 13(1):59–65PubMedCrossRefGoogle Scholar
  15. 15.
    Sioris T, Sihvo E, Salo J, Räsänen J, Knuuttila A (2009) Long-term indwelling pleural catheter (PleurX) for malignant pleural effusion unsuitable for talc pleurodesis. Eur J Surg Oncol 35(5):546–551PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Department of Thoracic SurgeryGlenfield HospitalLeicesterUK

Personalised recommendations