Abstract
This paper introduces a new Light Aspiration device for in vivo Soft TIssue Characterization (LASTIC). This device is designed to be used during surgery, and can undergo sterilization. It provides interactive-time estimation of the elastic parameters. LASTIC is a 3cm x 3cm metallic cylinder divided in two compartments. The lower compartment is a cylindrical chamber made airtight by a glass window in which a negative pressure can be applied. Put in contact with soft tissues, it can aspirate the tissues into the chamber through a circular aperture in its bottom side. The upper compartment is clinched onto the lower part. A miniature digital camera is fixed inside the upper chamber, focusing on the aspirated soft tissue. LASTIC is operated by applying a range of negative pressures in the lower compartment while measuring the resulting aspirated tissue deformations with the digital camera. These measurements are used to estimate the tissue elasticity parameters by inverting a Finite Element model of the suction experiment. In order to use LASTIC during surgical interventions, a library-based optimization process is used to provide an interactive time inversion.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Ottensmeyer, M.P.: Minimally invasive instrument for in vivo measurement of solid organ mechanical impedance. PhD thesis, Massachusetts Institute of Technology. Dept. of Mechanical Engineering (2001)
Gefen, A., Margulies, S.: Are in vivo and in situ brain tissues mechanically similar? J. Biomech. 37(9), 1339–1352 (2004)
Kerdok, A.E., Ottensmeyer, M.P., Howe, R.D.: Effects of perfusion on the viscoelastic characteristics of liver. J. Biomech. 39(12), 2221–2231 (2006)
Carter, F.J., Frank, T.G., Davies, P.J., McLean, D., Cuschieri, A.: Measurements and modelling of the compliance of human and porcine organs. Med. Image Anal. 5(4), 231–236 (2001)
Samur, E., Sedef, M., Basdogan, C., Avtan, L., Duzgun, O.: A robotic indenter for minimally invasive measurement and characterization of soft tissue response. Med. Image Anal. 11(4), 361–373 (2007)
Agache, P.G., Monneur, C., Leveque, J.L., Rigal, J.D.: Mechanical properties and young’s modulus of human skin in vivo. Arch. Dermatol. Res. 269(3), 221–232 (1980)
Jemec, G.B., Selvaag, E., Agren, M., Wulf, H.C.: Measurement of the mechanical properties of skin with ballistometer and suction cup. Skin Res. Technol. 7(2), 122–126 (2001)
Grahame, R., Holt, P.J.: The influence of ageing on the in vivo elasticity of human skin. Gerontologia 15(2), 121–139 (1969)
Vuskovic, V.: Device for in-vivo measurement of mechanical properties of internal human soft tissues. PhD thesis, ETH Zürich (2001)
Diridollou, S., Patat, F., Gens, F., Vaillant, L., Black, D., Lagarde, J.M., Gall, Y., Berson, M.: In vivo model of the mechanical properties of the human skin under suction. Skin Res. Technol. 6(4), 214–221 (2000)
Mazza, E., Nava, A., Bauer, M., Winter, R., Bajka, M., Holzapfel, G.A.: Mechanical properties of the human uterine cervix: an in vivo study. Med. Image Anal. 10(2), 125–136 (2006)
Wang, Q., Kong, L., Sprigle, S., Hayward, V.: Portable gage for pressure ulcer detection. In: Engineering in Medicine and Biology Society, 2006. EMBS 2006. 28th Annual International Conference of the IEEE, pp. 5997–6000 (2006)
Nava, A., Mazza, E., Furrer, M., Villiger, P., Reinhart, W.H.: In vivo mechanical characterization of human liver. Med. Image Anal. 12(2), 203–216 (2008)
Schiavone, P., Chassat, F., Boudou, T., Promayon, E., Valdivia, F., Payan, Y.: In vivo measurement of human brain elasticity using a light aspiration device. Med. Image Anal. 13, 673–678 (2009)
Niu, X., Jakatdar, N., Bao, J., Spanos, C.J.: Specular spectroscopic scatterometry. IEEE Transactions on Semiconductor Manufacturing 14(2), 97–111 (2001)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2010 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Schiavone, P., Promayon, E., Payan, Y. (2010). LASTIC: A Light Aspiration Device for in vivo Soft TIssue Characterization. In: Bello, F., Cotin, S. (eds) Biomedical Simulation. ISBMS 2010. Lecture Notes in Computer Science, vol 5958. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11615-5_1
Download citation
DOI: https://doi.org/10.1007/978-3-642-11615-5_1
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-11614-8
Online ISBN: 978-3-642-11615-5
eBook Packages: Computer ScienceComputer Science (R0)