Abstract
Nasal polyposis represents the end point of multiple inflammatory pathways. Radiological findings for polyposis demonstrate benign-appearing expansile lesions with soft tissue attenuation, occasional evidence of bony rarefaction, and rare evidence of bony erosion. When appropriately directed medical management, including topical and oral corticosteroids, culture-directed antibiotics, and specific treatments (e.g., immunotherapy), either fails or is contraindicated, surgery is warranted in the symptomatic patient with nasal polyps. Meticulous dissection with mucosa-sparing techniques during functional endoscopic sinus surgery can successfully eliminate polypoid disease; however, in the absence of postoperative care and medical management, recurrence is highly likely within a variable period of time. Further investigation into the optimal perioperative medical management is needed in order to ensure optimal surgical results.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Anderson H (1943) Nasal polyps and hyperplastic sinusitis. Thanning & Appel, Copenhagen
Blumstein G, Tuft L (1957) Allergy treatment in recurrent nasal polyposis. Its importance and value. Am J Med Sci 234:269–280
Busaba NY, de Oliveira LV et al (2005) Correlation between preoperative clinical diagnosis and histopathological findings in patients with rhinosinusitis. Am J Rhinol 19(2):153–157
Eberhart LH, Folz BJ et al (2003) Intravenous anesthesia provides optimal surgical conditions during microscopic and endoscopic sinus surgery. Laryngoscope 113(8):1369–1373
English GM (1986) Nasal polypectomy and sinus surgery in patients with asthma and aspirin idiosyncrasy. Laryngoscope 96(4):374–380
Kennedy DW (1985) Functional endoscopic sinus surgery. Technique. Arch Otolaryngol 111(10):643–649
Kennedy DW (1992) Prognostic factors, outcomes, and staging in ethmoid sinus surgery. Laryngoscope 102(12 pt 2 Suppl 57):1–18
Kennedy DW (2006) Technical innovations and the evolution of endoscopic sinus surgery. Ann Otol Rhinol Laryngol Suppl 196:3–12
Kern R, Schenck H (1933) Allergy: a constant factor in the etiology of so-called mucous nasal polyps. J Allergy 4:483
Krouse HJ, Krouse JH et al (1997) Endoscopic sinus surgery in otorhinolaryngology nursing using powered instrumentation. ORL Head Neck Nurs 15(2):22–26
Larsen PL, Tos M (1989) Nasal polyps: epithelium and goblet cell density. Laryngoscope 99(12):1274–1280
Larsen PL, Tos M et al (1986) Nasal glands and goblet cells in chronic hypertrophic rhinitis. Am J Otolaryngol 7(1):28–33
Linder A, Karlsson-Paraa A et al (1993) Immunocompetent cells in human nasal polyp and nasal mucosa. Rhinology 3:125–192
Mabry RL (1978) Intraturbinal steroid injection: indications, results, and complications. South Med J 71(7):789–791; 794
Mahfouz ME, Elsheikh MN et al (2006) Molecular profile of the antrochoanal polyp: up-regulation of basic fibroblast growth factor and transforming growth factor beta in maxillary sinus mucosa. Am J Rhinol 20(4):466–470
Majima Y (2004) Clinical implications of the immunomodulatory effects of macrolides on sinusitis. Am J Med 117(suppl 9A):20S–25S
Martin PA, Church CA et al (2003) Visual loss after intraturbinate steroid injection. Otolaryngol Head Neck Surg 128(2):280–281
McCleve D, Goldstein J et al (1978) Corticosteroid injections of the nasal turbinates: past experience and precautions. Otolaryngology 86(6 pt 1):ORL-851–857
Mogensen C, Tos M (1977) Density of goblet cells on normal adult nasal turbinates. Anat Anz 142(4):322–330
Moloney JR (1977) Nasal polyps, nasal polypectomy, asthma, and aspirin sensitivity. Their association in 445 cases of nasal polyps. J Laryngol Otol 91(10):837–846
Moloney JR, Collins J (1977) Nasal polyps and bronchial asthma. Br J Dis Chest 71(1):1–6
Ogawa H (1986) Atopic aspect of eosinophilic nasal polyposis and a possible mechanism of eosinophil accumulation. Acta Otolaryngol Suppl 430:12–17
Pawankar R (2003) Nasal polyposis: an update: editorial review. Curr Opin Allergy Clin Immunol 3(1):1–6
Pawankar R (2005) Mast cells in allergic airway disease and chronic rhinosinusitis. Chem Immunol Allergy 87:111–129
Rojas R, Palacios E (2005) Giant antrochoanal polyp: MRI findings. Ear Nose Throat J 84(3):130
Romashko AA, Stankiewicz JA (2005) Routine histopathology in uncomplicated sinus surgery: is it necessary? Otolaryngol Head Neck Surg 132(3):407–412; discussion 413
Saiman L, Marshall BC et al (2003) Azithromycin in patients with cystic fibrosis chronically infected with Pseudomonas aeruginosa: a randomized controlled trial. JAMA 290(13):1749–1756
Setliff RC III (1996) The hummer: a remedy for apprehension in functional endoscopic sinus surgery. Otolaryngol Clin North Am 29(1):95–104
Setliff RC III, Parsons DS (1994) The “Hummer”: new instrumentation for functional endoscopic sinus surgery. Am J Rhinol 8:275–278
Settipane G (1987) Nasal polyposis: epidemiology, pathology, immunology, and treatment. Am J Rhinol 1:119–126
Shankar L, Evans K et al (2006) Atlas of imaging of the paranasal sinuses. Informa Healthcare, London
Siddiqui J (2004) Immunomodulatory effects of macrolides: implications for practicing clinicians. Am J Med 117(Suppl 9A):26S–29S
Stammberger H (1991) Functional endoscopic sinus surgery: the Messerklinger technique. BC Decker, Philadelphia
Tos M, Morgensen C (1977) Density of mucous glands in the normal adult nasal turbinates. Arch Otorhinolaryngol 215(2):101–111
Tos M, Mogensen C (1977) Pathogenesis of nasal polyps. Rhinology 15(2):87–95
Wormald PJ, van Renen G et al (2005) The effect of the total intravenous anesthesia compared with inhalational anesthesia on the surgical field during endoscopic sinus surgery. Am J Rhinol 19(5):514–520
Zuckerkandl E (1882) Normale und Pathologische Anatomie der Nasenhöhle und ihrer pneumatischen Anhänge. W. Braumüller, Wien
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2010 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Welch, K.C., Kennedy, D.W. (2010). Surgical Treatment of Nasal Polyposis. In: Önerci, T., Ferguson, B. (eds) Nasal Polyposis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11412-0_29
Download citation
DOI: https://doi.org/10.1007/978-3-642-11412-0_29
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-11411-3
Online ISBN: 978-3-642-11412-0
eBook Packages: MedicineMedicine (R0)