Summary
Two conceptually different approaches to incorporate growth uncertainty into size-structured population models have recently been investigated. One entails imposing a probabilistic structure on all the possible growth rates across the entire population, which results in a growth rate distribution model. The other involves formulating growth as a Markov stochastic diffusion process, which leads to a Fokker-Planck model. Numerical computations verify that a Fokker-Planck model and a growth rate distribution model can, with properly chosen parameters, yield quite similar time dependent population densities. The relationship between the two models is based on the theoretical analysis in [7].
This research was supported in part (HTB and SH) by grant number R01AI071915-07 from the National Institute of Allergy and Infectious Diseases, in part (HTB and SH) by the Air Force Office of Scientific Research under grant number FA9550-09-1-0226 and in part (JLD) by the US Department of Energy Computational Science Graduate Fellowship under grant DE-FG02-97ER25308.
On the occasion of the 2009 Festschrift in honor of Chris Byrnes and Anders Lindquist.
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References
Allen, L.J.S.: An Introduction to Stochastic Processes with Applications to Biology. Prentice Hall, New Jersey (2003)
Banks, H.T., Bihari, K.L.: Modelling and estimating uncertainty in parameter estimation. Inverse Problems 17, 95–111 (2001)
Banks, H.T., Bokil, V.A., Hu, S., Dhar, A.K., Bullis, R.A., Browdy, C.L., Allnutt, F.C.T.: Modeling shrimp biomass and viral infection for production of biological countermeasures, CRSC-TR05-45, NCSU, December, 2005. Mathematical Biosciences and Engineering 3, 635–660 (2006)
Banks, H.T., Bortz, D.M., Pinter, G.A., Potter, L.K.: Modeling and imaging techniques with potential for application in bioterrorism, CRSC-TR03-02, NCSU, January, 2003. In: Banks, H.T., Castillo-Chavez, C. (eds.) Bioterrorism: Mathematical Modeling Applications in Homeland Security. Frontiers in Applied Math, vol. FR28, pp. 129–154. SIAM, Philadelphia (2003)
Banks, H.T., Botsford, L.W., Kappel, F., Wang, C.: Modeling and estimation in size structured population models, LCDS-CCS Report 87-13, Brown University. In: Proceedings 2nd Course on Mathematical Ecology, Trieste, December 8-12, 1986, pp. 521–541. World Press, Singapore (1988)
Banks, H.T., Davis, J.L.: Quantifying uncertainty in the estimation of probability distributions, CRSC-TR07-21, December, 2007. Math. Biosci. Engr. 5, 647–667 (2008)
Banks, H.T., Davis, J.L., Ernstberger, S.L., Hu, S., Artimovich, E., Dhar, A.K., Browdy, C.L.: A comparison of probabilistic and stochastic formulations in modeling growth uncertainty and variability, CRSC-TR08-03, NCSU, February, 2008. Journal of Biological Dynamics 3, 130–148 (2009)
Banks, H.T., Davis, J.L., Ernstberger, S.L., Hu, S., Artimovich, E., Dhar, A.K.: Experimental design and estimation of growth rate distributions in size-structured shrimp populations, CRSC-TR08-20, NCSU, November 2008. Inverse Problems (to appear)
Banks, H.T., Fitzpatrick, B.G., Potter, L.K., Zhang, Y.: Estimation of probability distributions for individual parameters using aggregate population data, CRSC-TR98-6, NCSU, January, 1998. In: McEneaney, W., Yin, G., Zhang, Q. (eds.) Stochastic Analysis, Control, Optimization and Applications, pp. 353–371. Birkhäuser, Boston (1998)
Banks, H.T., Fitzpatrick, B.G.: Estimation of growth rate distributions in size structured population models. Quart. Appl. Math. 49, 215–235 (1991)
Banks, H.T., Hu, S.: An equivalence between nonlinear stochastic Markov processes and probabilistic structures on deterministic systems (in preparation)
Banks, H.T., Tran, H.T.: Mathematical and Experimental Modeling of Physical and Biological Processes. CRC Press, Boca Raton (2009)
Banks, H.T., Tran, H.T., Woodward, D.E.: Estimation of variable coefficients in the Fokker-Planck equations using moving node finite elements. SIAM J. Numer. Anal. 30, 1574–1602 (1993)
Bell, G., Anderson, E.: Cell growth and division I. A mathematical model with applications to cell volume distributions in mammalian suspension cultures. Biophysical Journal 7, 329–351 (1967)
Chang, J.S., Cooper, G.: A practical difference scheme for Fokker-Planck equations. J. Comp. Phy. 6, 1–16 (1970)
Gard, T.C.: Introduction to Stochastic Differential Equations. Marcel Dekker, New York (1988)
Gyllenberg, M., Webb, G.F.: A nonlinear structured population model of tumor growth with quiescence. J. Math. Biol. 28, 671–694 (1990)
Kot, M.: Elements of Mathematical Ecology. Cambridge University Press, Cambridge (2001)
Luzyanina, T., Roose, D., Bocharov, G.: Distributed parameter identification for a label-structured cell population dynamics model using CFSE histogram time-series data. J. Math. Biol. (to appear)
Luzyanina, T., Roose, D., Schenkel, T., Sester, M., Ehl, S., Meyerhans, A., Bocharov, G.: Numerical modelling of label-structured cell population growth using CFSE distribution data. Theoretical Biology and Medical Modelling 4, 1–26 (2007)
Metz, J.A.J., Diekmann, O. (eds.): The Dynamics of Physiologically Structured Populations. Lecture Notes in Biomathematics. Springer, Berlin (1986)
Okubo, A.: Diffusion and Ecological Problems: Mathematical Models. Lecture Notes in Biomathematics, vol. 10. Springer, Berlin (1980)
Richtmyer, R.D., Morton, K.W.: Difference Methods for Initial-value Problems. Wiley, New York (1967)
Sinko, J., Streifer, W.: A new model for age-size structure of a population. Ecology 48, 910–918 (1967)
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Banks, H.T., Davis, J.L., Hu, S. (2010). A Computational Comparison of Alternatives to Including Uncertainty in Structured Population Models, . In: Hu, X., Jonsson, U., Wahlberg, B., Ghosh, B. (eds) Three Decades of Progress in Control Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11278-2_2
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