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Delayed Primary Anastomosis in the Management of Long-Gap Esophageal Atresia

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Abstract

In newborns with long-gap esophageal atresia, the esophageal segments are too far apart to allow primary anastomosis. Spontaneous growth and hypertrophy of the two esophageal segments occur at a rate faster than overall somatic growth in the absence of any form of mechanical stretching. The maximal natural growth arises in the first 8–12 weeks of life. The stimuli are the swallowing reflex and the reflux of gastric contents into the lower esophageal pouch. Therefore, initial gastrostomy and continuous suction of the upper esophageal pouch followed by delayed primary anastomosis is an ideal procedure for the management of newborns with long-gap esophageal atresia and provides good long-term functional results.

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References

  1. Depaepe A, Dolk H, Lechat MF. The epidemiology of tracheo-oesophageal fistula and oesophageal atresia in Europe. EUROCAT Working Group. Arch Dis Child. 1993;68:743–8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Torfs CP, Curry CJ, Bateson TF. Population-based study of tracheoesophageal fistula and esophageal atresia. Teratology. 1995;52:220–32.

    Article  CAS  PubMed  Google Scholar 

  3. Manning PB. Long-gap esophageal atresia. Semin Thorac Cardiovasc Surg. 1994;6:216–20.

    CAS  PubMed  Google Scholar 

  4. Langer JC, et al. Prenatal diagnosis of esophageal atresia using sonography and magnetic resonance imaging. J Pediatr Surg. 2001;36:804–7.

    Article  CAS  PubMed  Google Scholar 

  5. Stringer MD, et al. Prenatal diagnosis of esophageal atresia. J Pediatr Surg. 1995;30:1258–63.

    Article  CAS  PubMed  Google Scholar 

  6. Ladd WE. The surgical treatment of esophageal atresia and tracheoesophageal fistulas. N Engl J Med. 1944;230:625–37.

    Article  Google Scholar 

  7. Haight C, Towsley HA. Congenital atresia of esophagus with tracheoesophageal fistula: extrapleural ligation and end-to-end anastomosis of esophageal segments. Surg Gynecol Obstet. 1943;76:672–88.

    Google Scholar 

  8. Orford J, Cass DT, Glasson MJ. Advances in the treatment of oesophageal atresia over three decades: the 1970s and the 1990s. Pediatr Surg Int. 2004;20:402–7.

    Article  PubMed  Google Scholar 

  9. Goyal A, et al. Oesophageal atresia and tracheo-oesophageal fistula. Arch Dis Child Fetal Neonatal Ed. 2006;91:381–4.

    Article  Google Scholar 

  10. Chittmittrapap S, et al. Oesophageal atresia and associated anomalies. Arch Dis Child. 1989;64:364–8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Myers NA. Oesophageal atresia. Pediatr Surg Int. 1992;7:83–5.

    Article  Google Scholar 

  12. Holland AJ, et al. Surgical outcomes of esophageal atresia without fistula for 24 years at a single institution. J Pediatr Surg. 2009;44:1928–32.

    Article  PubMed  Google Scholar 

  13. Ron O, De Coppi P, Pierro A. The surgical approach to esophageal atresia repair and the management of long-gap atresia: results of a survey. Semin Pediatr Surg. 2009;18:44–9.

    Article  PubMed  Google Scholar 

  14. Myers NA. Oesophageal atresia: the epitome of modern surgery. Ann R Coll Surg Engl. 1974;54:277–87.

    CAS  PubMed  PubMed Central  Google Scholar 

  15. Howard R, Myers NA. Esophageal atresia: a technique for elongating the upper pouch. Surgery. 1972;71:661–4.

    Google Scholar 

  16. Lafer DJ, Boley SJ. Primary repair in esophageal atresia with elongation of the lower segment. J Pediatr Surg. 1966;1:585–7.

    Article  CAS  PubMed  Google Scholar 

  17. Rehbein F, Schweder N. Reconstruction of the esophagus without colon transplantation in cases of atresia. J Pediatr Surg. 1971;6:746–52.

    Article  CAS  PubMed  Google Scholar 

  18. Thomasson BH. Congenital esophageal atresia: mercury bag stretching of the upper pouch in a patient without tracheoesophageal fistula. Surgery. 1972;71:661–3.

    CAS  PubMed  Google Scholar 

  19. Livaditis A, Radberg L, Odensjo G. Esophageal end-to-end anastomosis: reduction of anastomotic tension by circular myotomy. Scand J Thorac Cardiovasc Surg. 1972;6:206–14.

    Article  CAS  PubMed  Google Scholar 

  20. Shafer AD, David TE. Suture fistula as a means of connecting upper and lower segments in esophageal atresia. J Pediatr Surg. 1974;9:669–73.

    Article  CAS  PubMed  Google Scholar 

  21. Hendren WH, Hale JR. Esophageal atresia treated by electromagnetic bougienage and subsequent repair. J Pediatr Surg. 1976;11:713–22.

    Article  CAS  PubMed  Google Scholar 

  22. Puri P, et al. Delayed primary anastomosis following spontaneous growth of esophageal segments in esophageal atresia. J Pediatr Surg. 1981;16:180–3.

    Article  CAS  PubMed  Google Scholar 

  23. Puri P, et al. Delayed primary anastomosis for esophageal atresia: 18 months’ to 11 years’ follow-up. J Pediatr Surg. 1992;27:1127–30.

    Article  CAS  PubMed  Google Scholar 

  24. Boyle Jr EM, Irwin ED, Foker JE. Primary repair of ultra-long-gap esophageal atresia: results without a lengthening procedure. Ann Thorac Surg. 1994;57:576–9.

    Article  PubMed  Google Scholar 

  25. Foker JE, et al. Development of a true primary repair for the full spectrum of esophageal atresia. Ann Surg. 1997;226:533–41.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Beasley SW, Myers NA, Auldist AW. Visualisation of the inferior pouch in oesophageal atresia without fistula. Pediatr Surg Int. 1999;15:451.

    Article  CAS  PubMed  Google Scholar 

  27. Rossi C, et al. A simple and safe method to visualize the inferior pouch in esophageal atresia without fistula. Pediatr Surg Int. 1998;13:535–6.

    Article  CAS  PubMed  Google Scholar 

  28. Puri P, Khurana S. Delayed primary esophageal anastomosis for pure esophageal atresia. Semin Pediatr Surg. 1998;7:126–9.

    Article  CAS  PubMed  Google Scholar 

  29. Caffarena PE, et al. Long-gap oesophageal atresia: a combined endoscopic and radiologic evaluation. Eur J Pediatr Surg. 1994;4:67–9.

    Article  CAS  PubMed  Google Scholar 

  30. Chan KL, Saing H. Combined flexible endoscopy and fluoroscopy in the assessment of the gap between the two esophageal pouches in esophageal atresia without fistula. J Pediatr Surg. 1995;30:668–70.

    Article  CAS  PubMed  Google Scholar 

  31. Gross ER, et al. The role of fiberoptic endoscopy in the evaluation and management of long gap isolated esophageal atresia. Pediatr Surg Int. 2010;26:1223–7.

    Article  PubMed  Google Scholar 

  32. Ratan SK, et al. Evaluation of neonates with esophageal atresia using chest CT scan. Pediatr Surg Int. 2004;20:757–61.

    Article  PubMed  Google Scholar 

  33. Tam PK, Chan FL, Saing H. Diagnosis and evaluation of esophageal atresia by direct sagittal CT. Pediatr Radiol. 1987;17:68–70.

    Article  CAS  PubMed  Google Scholar 

  34. Aziz D, et al. Can “long-gap” esophageal atresia be safely managed at home while awaiting anastomosis? J Pediatr Surg. 2003;38:705–8.

    Article  PubMed  Google Scholar 

  35. Ein SH, Shandling B, Heiss K. Pure esophageal atresia: outlook in the 1990s. J Pediatr Surg. 1993;28:1147–50.

    Article  CAS  PubMed  Google Scholar 

  36. Sri Paran T, et al. Long-term results of delayed primary anastomosis for pure oesophageal atresia: a 27-year follow up. Pediatr Surg Int. 2007;23:647–51.

    Article  PubMed  Google Scholar 

  37. Rosinha MC, et al. Delayed primary anastomosis for esophageal atresia without fistulae: 10 years of experience. Acta Med Port. 1997;10:173–7.

    CAS  PubMed  Google Scholar 

  38. Yeh SH, et al. Use of retrograde esophagoscopy in delayed primary esophageal anastomosis for isolated esophageal atresia. Eur J Pediatr Surg. 2010;20:40–4.

    Article  PubMed  Google Scholar 

  39. Howell CG, Davis Jr JB, Parrish RA. Primary repair of esophageal atresia: how long a gap? J Pediatr Surg. 1987;22:42–3.

    Article  CAS  PubMed  Google Scholar 

  40. Lobe TE, et al. Thoracoscopic repair of esophageal atresia in an infant: a surgical first. Pediatric Endosurg Innovative Tech. 1999;3:141–8.

    Article  Google Scholar 

  41. Buonuomo V, et al. Esophageal atresia: personal experience and review of the literature. Ann Ital Chir. 2007;78:385–8.

    PubMed  Google Scholar 

  42. Cavallaro S, et al. Feeding troubles following delayed primary repair of esophageal atresia. Eur J Pediatr Surg. 1992;2:73–7.

    Article  CAS  PubMed  Google Scholar 

  43. de la Hunt MN, Fleet MS, Wagget J. Delayed primary anastomosis for wide-defect esophageal atresia: a 17-year experience. Pediatr Surg Int. 1994;9:21–3.

    Article  Google Scholar 

  44. Healey PJ, et al. Delayed primary repair of esophageal atresia with tracheoesophageal fistula: is it worth the wait? Arch Surg. 1998;133:552–6.

    Article  CAS  PubMed  Google Scholar 

  45. Lindahl H, Rintala R, Louhimo I. Oesophageal anastomosis without bougienage in isolated atresia – do the segments really grow while waiting? Z Kinderchir. 1987;42:221–3.

    CAS  PubMed  Google Scholar 

  46. Rescorla FJ, et al. The complex nature of type A (long-gap) esophageal atresia. Surgery. 1994;116:658–64.

    CAS  PubMed  Google Scholar 

  47. Bensoussan AL, Letourneau JN, Blanchard H. Long gap esophageal atresia types 1 and 2 by delayed primary anastomosis: report on 6 cases. Chir Pediatr. 1983;24:109–12.

    CAS  PubMed  Google Scholar 

  48. Burjonrappa S, et al. Type a esophageal atresia: a critical review of management strategies at a single center. J Pediatr Surg. 2010;45:865–71.

    Article  PubMed  Google Scholar 

  49. Golonka NR, Hayashi AH. Early “sham” feeding of neonates promotes oral feeding after delayed primary repair of major congenital esophageal anomalies. Am J Surg. 2008;195:659–62.

    Article  PubMed  Google Scholar 

  50. Hagberg S, et al. Management of long-gap esophagus: experience with end-to-end anastomosis under maximal tension. Prog Pediatr Surg. 1986;19:88–92.

    Article  CAS  PubMed  Google Scholar 

  51. Hicks LM, Mansfield PB. Esophageal atresia and tracheoesophageal fistula: review of thirteen years’ experience. J Thorac Cardiovasc Surg. 1981;81:358–63.

    CAS  PubMed  Google Scholar 

  52. Ito T, Sugito T, Nagaya M. Delayed primary anastomosis in poor-risk patients with esophageal atresia associated with tracheoesophageal fistula. J Pediatr Surg. 1984;19:243–7.

    Article  CAS  PubMed  Google Scholar 

  53. Santos AD, et al. Correction of esophageal atresia with distal tracheoesophageal fistula. J Thorac Cardiovasc Surg. 1983;85:229–36.

    CAS  PubMed  Google Scholar 

  54. Wise Jr WE, Caniano DA, Harmel Jr RP. Tracheoesophageal anomalies in Waterston C neonates: a 30-year perspective. J Pediatr Surg. 1987;22:526–9.

    Article  PubMed  Google Scholar 

  55. Bagolan P, et al. Long gap esophageal atresia and esophageal replacement: moving toward a separation? J Pediatr Surg. 2004;39:1084–90.

    Article  CAS  PubMed  Google Scholar 

  56. Gurskas P, Ivanauskas A. Delayed primary anastomosis for esophageal atresia. Medicina. 2004;40:166–9.

    PubMed  Google Scholar 

  57. Hight DW, et al. Atresia of the esophagus: new trends in the management of high-risk neonates. Arch Surg. 1987;122:421–3.

    Article  CAS  PubMed  Google Scholar 

  58. Myers NA, et al. Oesophageal atresia without fistula – anastomosis or replacement? Pediatr Surg Int. 1987;2:216–22.

    Google Scholar 

  59. Ruiz de Temino M, et al. Esophageal atresia type I: is impossible possible? Cir Pediatr. 2006;19:39–45.

    CAS  PubMed  Google Scholar 

  60. Pieretti R, Shandling B, Stephens CA. Resistant esophageal stenosis associated with reflux after repair of esophageal atresia: a therapeutic approach. J Pediatr Surg. 1974;9:355–7.

    Article  CAS  PubMed  Google Scholar 

  61. Seguier-Lipszyc E, et al. The management of long gap esophageal atresia. J Pediatr Surg. 2005;40:1542–6.

    Article  PubMed  Google Scholar 

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Correspondence to Prem Puri .

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Puri, P., Friedmacher, F. (2017). Delayed Primary Anastomosis in the Management of Long-Gap Esophageal Atresia. In: Till, H., Thomson, M., Foker, J., Holcomb III, G., Khan, K. (eds) Esophageal and Gastric Disorders in Infancy and Childhood. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11202-7_21

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  • DOI: https://doi.org/10.1007/978-3-642-11202-7_21

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