Core Message
Long-term IGF-I treatment changed the craniofacial morphology and increased head circumference (i.e. brain growth) to normal values.
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References
Laron Z, Roitman A, Kauli R (1979) Effect of human growth hormone therapy on head circumference in children with hypopituitarism. Clin Endocrinol 10:393–399
Laron Z, Anin S, Klipper-Aubach Y, Klinger B (1992) Effects of insulin-like growth factor-I on linear growth, head circumference and body fat in patients with Laron-type dwarfism. Lancet 339:1258–1261
Leonard J, Samuels M, Cotterill AM, Savage MO (1994) Effects of recombinant insulin-like growth factor I on craniofacial morphology in growth hormone insensitivity. Acta Paediatr Suppl 399:140–141
Nellhaus G (1967) Head circumference from birth to eighteen years. Pediatrics 41:106–114
Scharf A, Laron Z (1972) Skull changes in pituitary dwarfism and the syndrome of familial dwarfism with high plasma immunoreactive growth hormone. A roentgenologic study. Horm Metab Res 4:93–97
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© 2011 Springer Berlin Heidelberg
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Laron, Z. (2011). IGF-I Stimulation of Head Growth in Patients with Laron Syndrome. In: Laron, Z., Kopchick, J. (eds) Laron Syndrome - From Man to Mouse. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11183-9_43
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DOI: https://doi.org/10.1007/978-3-642-11183-9_43
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