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The neurological findings encountered in patients with Laron syndrome were headaches, few epileptic episodes not always related to hypoglycemia, low back pain probably connected with the spinal stenosis found in few patients.
MR imaging revealed white matter pathology in some patients, leading to varying degrees of psychomotor disturbances. Two patients with diabetes mellitus developed neuropathy.
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References
Laron Z (2002) Growth hormone and insulin-like growth factor-I: effects on the brain, chap 85. In: Pfaff DW, Arnold AP, Etgen AM, Fahrbach SE, Rubin RT (eds) Hormones, brain and behavior. Academic, San Diego, pp 75–96
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© 2011 Springer Berlin Heidelberg
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Laron, Z. (2011). Neurological Aspects in Laron Syndrome. In: Laron, Z., Kopchick, J. (eds) Laron Syndrome - From Man to Mouse. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11183-9_36
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DOI: https://doi.org/10.1007/978-3-642-11183-9_36
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Publisher Name: Springer, Berlin, Heidelberg
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Online ISBN: 978-3-642-11183-9
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