Core Message
Untreated Laron syndrome patients have symptomatic and asymptomatic hypoglycemia, but with progressing age some develop relative insulin resistance, glucose intolerance, even diabetes mellitus with its complications. IGF-I treatment increases insulin sensitivity and improves the HbA1c.
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Part of the results are based on the Thesis of Tzvia Karmon in partial fulfillment for the MD degree, Sackler Faculty of Medicine, Tel Aviv University.
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Laron, Z. (2011). Insulin Secretion and Carbohydrate Metabolism in Patients with Laron Syndrome: From Hypoglycemia to Diabetes Mellitus. In: Laron, Z., Kopchick, J. (eds) Laron Syndrome - From Man to Mouse. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11183-9_30
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DOI: https://doi.org/10.1007/978-3-642-11183-9_30
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