Abstract
The original intention of Lars Leksell when he initiated stereotactic radiosurgery (SRS) in 1951 was to treat functional disorders such as Parkinson disease, chronic pain syndromes, and psychiatric conditions. Nowadays, SRS is also an emerging technology in the treatment of focal and non-focal epilepsy. Clinical cessation of seizures following SRS was observed in patients treated for arteriovenous malformations (Heikkinen et al. 1989) and cavernous malformations (Regis et al. 2000). Lindquist promoted the idea of a new approach for epilepsy surgery with Gamma Knife™ (Elekta, Stockholm, Sweden) radiosurgery (Lindquist et al. 1991). We analyzed and present our experience in this field in an attempt to define the potential of Stereotactic Radiosurgery (SRS) in non lesional and lesional epilepsy patients. Our local clinical experience (27 patients), accumulated over the last seven years, mainly includes treatment of 14 mesial temporal lobe epilepsy patients, 11 cases of corpus callosotomy, 2 cases of hypothalamic hamartoma. We describe the methodology for imaging; target outlining, dose selection and treatment planning options and delivery using a linear accelerator Novalis System with a 6 MV of energy.
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Celis, M.A., Garduño, O.A.G., Moreno-Jiménez, S. (2011). Stereotactic Radiosurgery for Epilepsy. In: De Salles, A., et al. Shaped Beam Radiosurgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11151-8_19
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DOI: https://doi.org/10.1007/978-3-642-11151-8_19
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