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Pituitary Adenomas

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Abstract

Pituitary adenomas represent the most common neoplasms near the sella turcica and constitute approximately 10–12% of all intracranial tumors (Seegenschmiedt 2008; Sanno et al. 2003). Pituitary tumors are classified as microadenomas or macroadenomas based on size, with microadenomas defined as <10 mm in diameter and macroadenomas being ≥10 mm in diameter (Knisely and Sperduto 2008). Pituitary adenomas are also divided into two broad categories: functioning (67%) and non-functioning (33%). Functioning adenomas can be further subdivided by which hormone is secreted: prolactin (28% of all pituitary adenomas), growth hormone (23%), ACTH (8%), and others (such as TSH-producing and gonadotropin-producing, 7%; Committee of Brain Tumor Registry of Japan 2000; Thapar et al. 1997). Management of pituitary adenomas can include observation, medical management, surgical management, and radiation therapy.

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Authors and Affiliations

  1. Department of Radiation Oncology, Southern California Permanente Medical Group, Los Angeles, CA, 90027, USA

    Winston W. Lien

  2. Department of Neurosurgery, Southern California Permanente Medical Group, Los Angeles, CA, 90027, USA

    Joseph C. Chen

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  1. Winston W. Lien
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  2. Joseph C. Chen
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Correspondence to Joseph C. Chen .

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Editors and Affiliations

  1. David Geffen School of Medicine at UCLA, Department of Neurosurgery and Radiation, University of California, Le Conte Ave. 10495, Los Angeles, 90095, California, USA

    Antonio A. F. De Salles

  2. UCLA Medical Center, Department of Neurosurgery, University of California, Le Conte Ave 10945, Los Angeles, 90095, California, USA

    Alessandra Gorgulho

  3. David Geffen School of Medicine, Dept. Radiation Oncology, University of California, Los Angeles, UCLA Medical Plaza 200, Los Angeles, 90095, California, USA

    Nzhde Agazaryan

  4. , Department of Radiation Oncology, VU University Medical Center, De Boelelaan 1117, Amsterdam, 1081 HV, Netherlands

    Ben Slotman

  5. David Geffen School of Medicine at UCLA, Department of Radiation Oncology, University of California, UCLA Medical Plaza 200, Los Angeles, 90095, California, USA

    Michael Selch

  6. BrainLAB, Inc., Westbrook Corporate Center 3, Westchester, 60154, Illinois, USA

    Aaaron J. Burwick

  7. Shaped-Beam Radiosurgery, Varian Medical Systems, Inc., Hansen Way 3100, Palo Alto, 94304, California, USA

    Raymond Schulz

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Lien, W.W., Chen, J.C. (2011). Pituitary Adenomas. In: De Salles, A., et al. Shaped Beam Radiosurgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11151-8_10

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