Abstract
Survival depends upon efficient motor control behaviors which enable organisms to navigate through their environment, search for food, find a mate and avoid predation. In this chapter we provide an overview of motor systems that generate movements in a range of different animals. In vertebrates and invertebrates alike motor systems are similar: central networks drive motoneurons to fire which in turn elicit contractions in skeletal muscles to articulate the joints of the limbs or segments of the body. Biomechanical constraints influence behavior, and once behavior is produced sensory information is generated that feeds back and in turn modulates motor control. The components of motor systems, including motoneurons, muscles with their electrical and mechanical properties as well as sensory feedback are present across different phyla but the ways in which they are assembled during development have been sculpted into different species-specific solutions by the forces of natural selection.
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References
Ballantyne D, Rathmayer W (1981) On the function of the common inhibitory neurone in the walking legs of the crab, Eriphia spinifrons. J Comp Physiol 143:111–122
Baro DJ, Cole CL, Harris-Warrick RM (1996) RT-PCR analysis of shaker, shab, shaw, and shal gene expression in single neurons and glial cells. Receptor Channel 4:149–159
Boothby KM, Roberts A (1995) Effects of site of tactile stimulation on the escape swimming responses of hatchling Xenopus laevis embryos. J Zool 235:113–125
Büschges A (2005) Sensory control and organization of neural networks mediating coordination of multisegmental organs for locomotion. J Neurophysiol 93:1127–1135
Burrows M (1996) The neurobiology of an insect brain. Oxford University Press, Oxford
Burrows M, Hoyle G (1973) Neural mechanism underlying behavior in the locust Schistocerca gregaria. III. Topography of limb motorneurons in the metathoracic ganglion. J Neurobiol 4:167–186
Casasnovas B, Meyrand P (1995) Functional differentiation of adult neural circuits from a single embryonic network. J Neurosci 15:5703–5718
Clarac F, Libersat F, Pflüger HJ, Rathmayer W (1987) Motor pattern analysis in the shore crab (Carcinus maenas) walking freely in water and on land. J Exp Biol 133:395–414
Clarac F, Pearlstein E, Pflieger JF, Vinay L (2004) The in vitro neonatal rat spinal cord preparation: a new insight into mammalian locomotor mechanisms. J Comp Physiol A 190:343–357
Cruse H (1990) What mechanisms coordinate leg movement in walking arthropods? Trends Neurosci 13:15–21
Duch C, Pflüger HJ (1995) Motor patterns for horizontal and upside-down walking and vertical climbing. J Exp Biol 198:1963–1976
Duch C, Bayline RJ, Levine RB (2000) Postembryonic development of the dorsal longitudinal flight muscle and its innervation in Manduca sexta. J Comp Neurol 422:1–17
Ducret E, Le Feuvre Y, Meyrand P, Fénelon VS (2007) Removal of GABA within adult modulatory systems alters electrical coupling and allows expression of an embryonic-like network. J Neurosci 27:3626–3638
Dumont JPC, Robertson RM (1986) Neuronal circuits: an evolutionary perspective. Science 233:849–853
Edwards DH, Heitler WJ, Krasne FB (1999) Fifty years of a command neuron: the neurobiology of escape behavior in the crayfish. Trends Neurosci 22:153–161
Evans PD, O’Shea M (1977) An octopaminergic neuron modulates neuromuscular transmission in the locust. Nature 270:257–259
Friesen WO, Kristan WB (2007) Leech locomotion: swimming, crawling, and decisions. Curr Opin Neurobiol 17:704–711
Furshpan EJ, Potter DD (1959) Transmission at the giant motor synapses of the crayfish. J Physiol 145:289–325
Getting PA (1983) Neural control of swimming in Tritonia. Symp Soc Exp Biol 37:89–128
Grillner S (2006) Biological pattern generation: the cellular and computational logic of networks in motion. Neuron 52:751–756
Grillner S, Deliagina T, Ekeberg O, El Manira A, Hill RH, Lansner A, Orlovsky GN, Wallén P (1995) Networks that co-ordinate locomotion and body orientation in lamprey. Trends Neurosci 18:270–279
Heitler WJ, Burrows M (1977) The locust jump. I. The motor programme. J Exp Biol 66:203–219
Heitler WJ, Burrows M (1977) The locust jump. II. Neural circuits of the motor programme. J Exp Biol 66:221–241
Hiebert GW, Whelan PJ, Prochazka A, Pearson KG (1996) Contribution of hindlimb flexor afferents to the timing of the phase transitions in the cat step cycle. J Neurophysiol 75:1126–1137
Hoyle G, Burrows M (1973) Neural mechanisms underlying behavior in the locust Schistocerca gregaria. I. Physiology of identified motorneurons in the metathoracic ganglion. J Neurobiol 4:3–41
Johnston IA (1980) Specialization of fish muscle. In: Goldspink DF (ed) Development and specialization of skeletal muscle. Society for Experimental Biology seminar series, vol 7. p 123–148
Kahn JA, Roberts A (1982) The neuromuscular basis of rhythmic struggling movements in embryos of Xenopus laevis J Exp Biol 99:197–205
Katz PS (1998) Neuromodulation intrinsic to the central pattern generator for escape swimming in Tritonia. Ann N Y Acad Sci 860:181–188
Kiehn O, Sillar KT, Kjaerulff O, McDearmid JR (1999) Effects of noradrenaline on locomotor rhythm generating networks in the isolated neonatal rat spinal cord. J Neurophysiol 82:741–746
Kim YJ, Zitnan D, Galizia GC, Cho KH, Adams ME (2006) A command chemical triggers an innate behavior by sequential activation of multiple peptidergic ensembles. Curr Biol 16:1395–1407
Kriellaars DJ, Brownstone RM, Noga BR, Jordan LM (1994) Mechanical entrainment of fictive locomotion in the decerebrate cat. J Neurophysiol 71:2074–2086
Kristan WB (1983) The neurobiology of swimming in the leech. Trends Neurosci 6:84–88
Kullander K, Butt SJB, Lebret JM, Lundfald L, Restrepo CE, Rydstrom A, Klein R, Kiehn O (2003) Role of EphA4 and EphrinB3 in local neuronal circuits that control walking. Science 299:1889–1892
Levine RB, Morton DB, Restifo LL (1995) Remodeling of the insect nervous system. Curr Opin Neurobiol 5:28–35
Li WC, Soffe SR, Wolf E, Roberts A (2006) Persistent Responses to brief stimuli: feedback excitation among brainstem neurons J Neurosci 26:4026–4035
Li WC, Sautois B, Roberts A, Soffe SR (2007) Reconfiguration of a vertebrate motor network: specific neuron recruitment and context-dependent synaptic plasticity J Neurosci 27:12267–12276
Liao C (2004) Neuromuscular control of trout swimming in a vortex street: implications for energy economy during the Karman gait. J Exp Biol 207:3495–3506
Maier L, Rathmayer W, Pette D (1984) pH lability of myosin ATPase activity permits discrimination of different muscle fibre types in crustaceans. Histochemistry 81:75–77
Maier L, Pette D, Rathmayer W (1986) Enzyme activities in single electrophysiologically identified crab muscle fibres. J Physiol 371:191–199
Marder E (2002) Non-mammalian models for studying neural development and function. Nature 417:318–321
Marder E, Bucher D (2001) Central pattern generators and the control of rhythmic movement. Curr Biol 11:R986–R996
Marder E, Bucher D (2007) Understanding circuit dynamics using the stomatogastric nervous system of lobsters and crabs. Annu Rev Physiol 69:291–316
Marden JH, Kramer MG (1997) Locomotor performance of insects with rudimentary wings. Nature 377:332–334
McLean DL, Fetcho JR (2008) Using imaging and genetics in zebrafish to study developing spinal circuits in vivo. Dev Neurobiol 68:817–834
Mentel T, Duch C, Stypa H, Wegener G, Müller U, Pflüger HJ (2003) Central modulatory neurons control fuel selection in flight muscle of migratory locust. J Neurosci 23:1109–1113
Mesce KA (2002) Metamodulation of the biogenic amines: second-order modulation by steroid hormones and amine cocktails. Brain Behav Evol 60:339–349
Möhl B (1988) Short-term learning during flight control in Locusta migratoria. J Comp Physiol A 163:803–812
Müller KJ, Nicholls JG, Stent GS (eds) (1981) Neurobiology of the leech. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, pp 113–146
Nachtigall W (1989) Mechanics and aerodynamics of flight. In: Goldsworthy GH, Wheeler CH (eds) Insect flight. CRC Press, Boca Raton, pp 1–29
Pflüger HJ, Duch C (2011) Dynamic neural control of muscle metabolism related to motor behavior. Physiology (Bethesda) 26:293–303
Reichert H (1992) Introduction to Neurobiology. Georg Thieme Verlag, Stuttgart and New York
Reichert H, Simeone A (2001) Developmental genetic evidence for a monophyletic origin of the bilaterian brain. Philos Trans R Soc Lond B Biol Sci 356:1533–1544
Richter DW, Spyer KM (2001) Studying rhythmogenesis of breathing: comparison of in vivo and in vitro models. Trends Neurosci 24:464–472
Richerson GB (2004) Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis. Nat Rev Neurosci 5:449–461
Roberts A, Li WC, Soffe SR (2010) How neurons generate behavior in a hatchling amphibian tadpole: an outline. Front Behav Neurosci 4:1–11
Sillar KT (2009) Mauthner cells. Curr Biol 19:R353–R355
Sillar KT, Li WC (2010) Tadpole swimming circuit. In: Shepherd GM, Grillner S (eds) Handbook of brain microcircuits. Oxford University Press, Oxford/New York
Sillar KT, Combes D, Ramanathan S, Molinari M, Simmers AJ (2008) Neuromodulation and developmental plasticity in the locomotor system of anuran amphibians during metamorphosis. Special issue on “networks in motion”. Brain Res Rev 57:94–102
Skiebe P (1999) Allatostatin-like immunoreactivity in the stomatogastric nervous system and the pericardial organs of the crab Cancer pagurus, the lobster Homarus americanus, and the crayfish Cherax destructor and Procambarus clarkii. J Comp Neurol 403:85–105
Sprecher SG, Reichert H (2003) The urbilaterian brain: developmental insights into the evolutionary origin of the brain in insects and vertebrates. Arthropod Struct Dev 32:141–156
Stevenson PA, Kutsch W (1988) Demonstration of functional connectivity of the flight motor system in all stages of the locust. J Comp Physiol A 162:247–259
Strauss R (2002) The central complex and the genetic dissection of locomotor behaviour. Curr Opin Neurobiol 12:633–638
Stuart DG, Hultborn H (2008) Thomas Graham Brown (1882–1965), Anders Lundberg (1920–2009), and the neural control of stepping. Brain Res Rev 59:74–95
Watkins BL, Burrows M, Siegler MVS (1985) The structure of locust nonspiking interneurones in relation to their segmental ganglion. J Comp Neurol 240:233–255
Weeks JC (2003) Thinking globally, acting locally: steroid hormone regulation of the dendritic architecture, synaptic connectivity, and death of an individual neuron. Prog Neurobiol 70:421–442
Wiens TJ, Wolf H (1993) The inhibitory motoneurons of crayfish thoracic limbs: identification, structures, and homology with insect common inhibitors. J Comp Neurol 336:261–278
Wilson DM (1961) The central nervous control of locust flight. J Exp Biol 38:472–490
Wolf H (1990) Activity patterns of inhibitory motoneurons and their impact on leg movement in tethered walking locusts. J Exp Biol 152:281–304
Wolf H, Pearson KG (1988) Proprioceptive input patterns elevator activity in the locust flight system. J Neurophysiol 59:1831–1853
Yeh SR, Fricke RA, Edwards DH (1996) The effect of social experience on serotonergic modulation of the escape circuit of crayfish. Science 271:366–369
Zitnan D, Hollar L, Spalovska I, Takac P, Zitnanova I, Gill SS, Adams ME (2002) Molecular cloning and function of ecdysis-triggering hormones in the silkworm Bombyx mori. J Exp Biol 205:3459–3473
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Pflüger, HJ., Sillar, K. (2013). Motor Control. In: Galizia, C., Lledo, PM. (eds) Neurosciences - From Molecule to Behavior: a university textbook. Springer Spektrum, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-10769-6_23
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DOI: https://doi.org/10.1007/978-3-642-10769-6_23
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