Abstract
Venous oxygen saturation is a clinical tool which integrates the whole body oxygen uptake-to-delivery (VO2-DO2) relationship. In the clinical setting, in the absence of pulmonary artery catheter (PAC)-derived mixed venous oxygen saturation (SvO2), the central venous oxygen saturation (ScvO2) is increasingly being used as a reasonably accurate surrogate [1]. Central venous catheters (CVCs) are simpler to insert, and generally safer and cheaper than PACs. The CVC allows sampling of blood for measurement of ScvO2 or even continuous monitoring if an oximetry catheter is being used. The normal range for SvO2 is 68 to 77 % and ScvO2 is considered to be 5 % above these values [2].
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Dueck MH, Klimek M, Appenrodt S, Weigand C, Boerner U (2005) Trends but not individual values of central venous oxygen saturation agree with mixed venous oxygen saturation during varying hemodynamic conditions. Anesthesiology 103: 249–257
Reinhart K, Kuhn HJ, Hartog C, Bredle DL (2004) Continuous central venous and pulmonary artery oxygen saturation monitoring in the critically ill. Intensive Care Med 30: 1572–1578
Räsänen J (1990) Mixed venous oximetry may detect critical oxygen delivery. Anesth Analg 71: 567–568
Vallet B, Singer M (2006) Hypotension. In: Ramsay G (ed) Patient-Centred Acute Care Training, First Edition. European Society of Intensive Care Medicine, Brussels
Ronco JJ, Fenwick JC, Tweeddale MG, et al (1993) Identification of the critical oxygen delivery for anaerobic metabolism in critically ill septic and nonseptic humans. JAMA 270: 1724–1730
Rivers E, Nguyen B, Havstad S, et al (2001) Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345: 1368–1377
Adamczyk S, Robin E, Barreau O, et al (2009) [Contribution of central venous oxygen saturation in postoperative blood transfusion decision]. Ann Fr Anesth Reanim 28: 522–530
Conférence de consensus (2003) Société de réanimation de langue française — XXIIIe Conférence de consensus en réanimation et en médecine d’urgence — jeudi 23 octobre 2003: Transfusion érythrocytaire en réanimation (nouveau-né exclu). Réanimation 12: 531–537
van Woerkens EC, Trouwborst A, van Lanschot JJ (1992) Profound hemodilution: what is the critical level of hemodilution at which oxygen delivery-dependent oxygen consumption starts in an anesthetized human? Anesth Analg 75: 818–821
Lieberman JA, Weiskopf RB, Kelley SD, et al (2000) Critical oxygen delivery in conscious humans is less than 7.3 mLO2.kg−1.min−1. Anesthesiology 92: 407–413
Leung JM, Weiskopf RB, Feiner J, et al (2000) Electrocardiographic ST-segment changes dur ing acute, severe isovolemic hemodilution in humans. Anesthesiology 93: 1004–1010
Spahn DR, Zollinger A, Schlumpf RB, et al (1996) Hemodilution tolerance in elderly patients without known cardiac disease. Anesth Analg 82: 681–686
Spahn DR, Schmid ER, Seifert B, Pasch T (1996) Hemodilution tolerance in patients with coronary artery disease who are receiving chronic beta-adrenergic blocker therapy Anesth Analg 82: 687–694
Weiskopf RB, Feiner J, Hopf HW, et al (2002) Oxygen reverses deficits of cognitive function and memory and increased heart rate induced by acute severe isovolemic anemia. Anesthesiology 96: 871–877
Weiskopf RB, Toy P, Hopf HW, et al (2005) Acute isovolemic anemia impairs central processing as determined by P300 latency. Clin Neurophysiol 116: 1028–1032
Spahn DR, Madjdpour C (2006) Physiologic transfusion triggers: do we have to use (our) brain? Anesthesiology 104: 905–906
Weiskopf RB, Feiner J, Hopf H, et al (2006) Fresh blood and aged stored blood are equally efficacious in immediately reversing anemia-induced brain oxygenation deficits in humans. Anesthesiology 104: 911–920
Madjdpour C, Spahn DR, Weiskopf RB (2006) Anemia and perioperative red blood cell transfusion: a matter of tolerance. Crit Care Med 34: S102–108
Vallet B, Adamczyk S, Barreau O, Lebuffe G (2007) Physiologic transfusion triggers. Best Pract Res Clin Anaesthesiol 21: 173–181
Orlov D, O’Farrell R, McCluskey SA, et al (2009) The clinical utility of an index of global oxygenation for guiding red blood cell transfusion in cardiac surgery. Transfusion 49: 682–688
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2010 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Vallet, B., Robin, E., Lebuffe, G. (2010). Venous Oxygen Saturation as a Physiologic Transfusion Trigger. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine 2010. Yearbook of Intensive Care and Emergency Medicine, vol 2010. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-10286-8_29
Download citation
DOI: https://doi.org/10.1007/978-3-642-10286-8_29
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-10285-1
Online ISBN: 978-3-642-10286-8
eBook Packages: MedicineMedicine (R0)