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Nanostructured Biomaterials pp 1–30Cite as

Silica-based Nanostructured Porous Biomaterials

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Part of the book series: Advanced Topics in Science and Technology in China ((ATSTC))

Abstract

Recently, the application of nanomaterials in medical and biological fields has become more important. Nanoparticles (NPs) have been used as sensors, fluorescent markers, clinical diagnoses, drug delivery and MRI contrast agents (Lin et al., 2005). Inorganic, porous, ceramic nanoparticles have several advantages in biological applications. They are readily engineered with the desired size, shape, and porosity, and are often inert. The ceramic materials have surfaces with hydroxyl groups, and thus they are always hydrophilic (Paul, Sharma, 2001; Roy et al., 2003; Gemeinhart et al., 2005). Such natural hydrophilicity can decrease oxide particle clearance by the immune system, and thus increases their circulation time in blood (Barbe et al., 2004). Growing interest has recently emerged in utilizing porous ceramic nanomaterials as carriers in biological systems, exploring typical biocompatible ceramic nanoparticles, such as silica, alumina, and titania (Yih, Al-Fandi, 2006).

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Authors and Affiliations

  1. National Center for Nanoscicence and Technology, Beijing, 100190, China

    Yang Yang

  2. Beijing National Laboratory for Molecular Sciences (BNLMS), International Joint Lab, CAS Key Lab of Colloid and Interface Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China

    Junbai Li

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  1. Key Lab of the Colloid and Interface Sciences International Joint Lab with the German Max Planck Institute of Colloids & Interfaces Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China

    Junbai Li

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Yang, Y., Li, J. (2010). Silica-based Nanostructured Porous Biomaterials. In: Li, J. (eds) Nanostructured Biomaterials. Advanced Topics in Science and Technology in China. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-05012-1_1

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