Zusammenfassung
Weichgewebesarkome des Erwachsenen stellen diagnostisch anspruchsvolle und therapeutisch komplexe Erkrankungen dar. Die Heterogenität mit diversen, biologisch sehr differenten histologischen Subtypen, verbunden mit der Seltenheit der Erkrankung, behindert das Fortschreiten des Erkenntnisgewinns. In den letzten Jahren, generiert durch die molekulare Pathologie, wurde evident, dass das »Sammelsurium Weichgewebesarkome« eigenständige Entitäten beinhaltet, die differenzierte Therapieansätze benötigen. Dieser Wissensgewinn hat sich in der Mehrzahl der »adult type sarcomas« mit komplexen, heterogenen Genomveränderungen noch nicht in neue Therapieansätze transferieren lassen.
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Hartmann, J.T., Schütte, J. (2011). (Neo-)adjuvante medikamentöse Therapie. In: Weichgewebetumoren. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-04939-2_17
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DOI: https://doi.org/10.1007/978-3-642-04939-2_17
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