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Tumorbiologische und molekulargenetische Aspekte

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Hepatobiliäre und Pankreastumoren

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Zusammenfassung

Durch die Fortschritte in der Molekularbiologie und deren Applikation in der Tumorforschung können die molekularen Mechanismen analysiert werden, die zu unkontrolliertem Zellwachstum führen und damit die Karzinogenese induzieren. Die Definition neuer molekularer Pathways eröffnet Möglichkeiten, neue Strategien für Diagnostik, Intervention und Behandlung von Malignomen zu entwickeln. Das molekulare Verständnis der Tumorentstehung zeigt, weshalb die Behandlung häufig hoch komplex ist. Es wird uns aber in Zukunft helfen, individuelle Diagnostik durchzuführen und eine patientenbezogene Behandlungsstrategie zu entwickeln.

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  1. Klinik für Chirurgie, Universitätsklinikum Schleswig- Holstein, Ratzeburger Allee 160, 23538, Lübeck

    Dr. med. F. G. Bader, Prof. Dr. med. H.-P. Bruch, PD Dr. Dr. med. U.J. Roblick & PD Dr. Dr. med. J.K. Habermann

  2. Solna, Karolinska Universitetssjukhuset, 17176, Stockholm, Schweden

    Prof. Dr. med. G. Auer

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Bader, F.G., Auer, G., Bruch, HP., Roblick, U., Habermann, J. (2010). Tumorbiologische und molekulargenetische Aspekte. In: Hepatobiliäre und Pankreastumoren. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-04935-4_3

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