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Anatomie und Funktion

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Pathologie

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Zusammenfassung

Unter den beweglichen Knochenverbindungen, die als Juncturae fibrosae Schien- und Wadenbein verbinden, als Jj. cartilagineae von Zwischenwirbelscheiben und Symphyse repräsentiert werden und als Jj. synoviales die Spaltgelenke darstellen, gewähren Letztere als Diarthrosen die größte Bewegungsfreiheit.

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Notes

  1. 1.

    1 „Das schmalste Gelenk meiner Hand spottet aller Technik“ [36]

  2. 2.

    2 Es darf hier erwähnt werden, dass die „therapeutische“ intraartikuläre Hyaluronsäureinjektion klinisch ineffektiv ist [2].

Literatur

  1. Adams CS, Horton WE (1998) Chondrocyte apoptosis increases with age in the articular cartilage of adult animals. Anat Rec 250:418–425

    Article  CAS  PubMed  Google Scholar 

  2. Arrich J, Piribauer F, Mad P et al (2005) Intra-articular hyaluronic acid for the treatment of osteoarthritis of the knee: systematic review and meta-analysis. Can Med Assoc J 172:1039–1043

    Article  Google Scholar 

  3. Boland JM, Folpe AL, Hornick JL et al (2009) Clusterin is expressed in normal synoviocytes and in tenosynovial giant cell tumors of localized and diffuse types. Diagnostic and histogenetic implications. Am J Surg Pathol 33:1225–1229

    Article  PubMed  Google Scholar 

  4. Buckwalter JA, Mankin HJ, Grodzinsky AJ (2005) Articular cartilage and osteoarthritis. Instr Course Lect 54:465–480

    PubMed  Google Scholar 

  5. Coggeshall HC, Warren CF, Bauer W (1940) The cytology of normal human synovial fluid. Anat Rec 77:129–144

    Article  Google Scholar 

  6. Conde J, Gomez R, Bianco G et al (2011) Expanding the adipokine network in cartilage: identification and regulation of novel factors in human and murine chondrocytes. Ann Rheum Dis 70:551–559

    Article  CAS  PubMed  Google Scholar 

  7. Endres-Klein R (1949) Da „Der Remmele“ keinen Raum für Dankeschöns enthält, sei hier der bewährten Mitarbeiterin gedankt, die viel dazu beitrug, dass das Typoskript renoviert wurde (W.M.).

    Google Scholar 

  8. Fässler R, Schnegelsberg PNJ, Dausman J et al (1994) Mice lacking α 1(IX) collagen develop noninflammatory degenerative joint desease. Proc Natl Acad Sci USA 91:5070–5074

    Article  PubMed Central  PubMed  Google Scholar 

  9. Flannery CR, Hughes CE, Schumacher BL et al (1999) Articular cartilage superficial zone protein (SZP) is homologous to megakaryocyte stimulating factor precursor and is a multifunctional proteoglycan with potential growth-promoting, cytoprotective, and lubricating properties in cartilage metabolism. Biochem Biophys Res Commun 254:535–541

    Article  CAS  PubMed  Google Scholar 

  10. Garnero P, Rousseau J-C, Delmas (2000) Molecular basis and clinical use of biochemical markers of bone, cartilage, and synovium in joint diseases. Arthritis Rheum 43:953–968

    Article  CAS  PubMed  Google Scholar 

  11. Hu K, Xu L, Cao L et al (2006) Pathogenesis of osteoarthritis-like changes in the joints of mice deficient in type IX collagen. Arthritis Rheum 54:2891–2900

    Article  CAS  PubMed  Google Scholar 

  12. Iwanaga T, Shikichi M, Kitamura H et al (2000) Morphology and functional roles of synoviocytes in the joint. Arch Histol Cytol 63:17–31

    Article  CAS  PubMed  Google Scholar 

  13. Jay GD, Britt DE, Cha C-J (2000) Lubricin is a product of megakaryocyte stimulating factor gene expression by human synovial fibroblasts. J Rheumatol 27:594–600

    CAS  PubMed  Google Scholar 

  14. Jones ARC, Gleghorn JP, Hughes CE et al (2007) Binding and localization of recombinant lubricin to articular cartilage surfaces. J Orthop Res 25:283–292

    Article  CAS  PubMed  Google Scholar 

  15. Kasperkovitz PV, Timmer TC, Smeets TJ et al (2005) Fibroblast-like synoviocytes derived from patients with rheumatoid arthritis show the imprint of synovial tissue heterogeneity: evidence of a link between an increased myofibroblast-like phenotype and high-inflammation synovitis. Arthritis Rheum 52:430–441

    Article  PubMed  Google Scholar 

  16. Kielty CM, Grant ME (2002) The collagen family: Structure, assembly, and organization in the extracellular matrix. In: Royce PM, Steinmann B (Hrsg) Connective tissue and its heritable disorders. Molecular, genetic, and medical aspects, 2. Aufl. Wiley-Liss Inc, New York, S 159–221

    Chapter  Google Scholar 

  17. Lohmander LS, Saxne T, Heinegård D (1994) Release of cartilage oligomeric matrix protein (COMP) into joint fluid after knee injury and in osteoarthrosis. Ann Rheum Dis 53:8–13

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  18. Lorenzo P, Bayliss MT, Heinegård D (1998) A novel cartilage protein (CILP) present in the mid-zone of human articular cartilage increases with age. J Biol Chem 273:23463–23468

    Article  CAS  PubMed  Google Scholar 

  19. Löwenheim H, Reichl J, Winter H et al (2005) In vitro expansion of human nasoseptal chondrocytes reveals distinct expression profiles of G1 cell cycle inhibitors for replicative, quiescent, and senescent culture stages. Tissue Eng 11:64–75

    Article  PubMed  Google Scholar 

  20. Marcelino J, McDevitt CA (1995) Attachment of articular cartilage chondrocytes to the tissue form of typ VI collagen. Biochim Biophys Acta 1249:180–188

    Article  PubMed  Google Scholar 

  21. Mohr W (2000) Gelenkpathologie. Historische Grundlagen, Ursachen und Entwicklungen von Gelenkleiden und ihre Pathomorphologie. Springer, Berlin

    Google Scholar 

  22. Mohr W (2002) Kalkosphäriten als Grundstrukturen pathologischer und physiologischer Verkalkungen. Eine vergleichende Übersicht zu Beziehungen zwischen Arterienverkalkungen und Knochen. Osteologie 11:133–153

    Article  Google Scholar 

  23. Mohr W (2003) Neutrophile Granulozyten bei der rheumatischen Gewebszerstörung. VIII. Überlegungen zur entzündlichen Knorpeldestruktion bei chronischen Arthritiden im Vergleich zu Leberschädigungen durch neutrophile Granulozyten. Z Rheumatol 62:539–546

    Article  CAS  PubMed  Google Scholar 

  24. Mohr W, Endres-Klein R (2003) Granuläre Transformation der Matrix des Nucleus pulposus menschlicher Zwischenwirbelscheiben. Osteologie 12:163–173

    Article  Google Scholar 

  25. Morawietz L, Gehrke T, Frommelt L et al (2003) Differential gene expression in the periprosthetic membrane: lubricin as a new possible pathogenetic factor in prosthesis loosening. Virchows Arch 443:57–66

    Article  CAS  PubMed  Google Scholar 

  26. Müller-Esterl W (2010) Biochemie. Eine Einführung für Mediziner und Naturwissenschaftler, 2. Aufl. Spektrum Akademischer Verlag, Heidelberg, S 106–107

    Google Scholar 

  27. Nadolny Sten (1987) Die Entdeckung der Langsamkeit. Piper, München Zürich

    Google Scholar 

  28. Nerlich AG, Schleicher ED, Boos N (1997) 1997 Volvo Award winner in basic science studies. Immunohistologic markers for age-related changes of human lumbar intervertebral discs. Spine 22:2781–2795

    Article  CAS  PubMed  Google Scholar 

  29. Otero M, Goldring MB (2007) Cells of the synovium in rheumatoid arthritis. Chondrocytes. Arthritis Res Ther 9:220–232

    Article  PubMed Central  PubMed  Google Scholar 

  30. Ottani V, Martini D, Franchi M et al (2002) Hierarchical structures in fibrillar collagens. Micron 33:587–596

    Article  CAS  PubMed  Google Scholar 

  31. Roughley PJ, Melching LI, Recklies AD (1994) Changes in the expression of decorin and biglycan in human articular cartilage with age and regulation by TGF-β. Matrix Biol 14:51–59

    Article  CAS  PubMed  Google Scholar 

  32. Schroeppel JP, Crist JD, Anderson HC et al (2011) Molecular regulation of articular chondrocyte function and its significance in osteoarthritis. Histol Histopathol 26:377–394

    CAS  PubMed  Google Scholar 

  33. Scotchford CA, Vickers M, Ali SY (1995) The isolation and characterization of magnesium whitlockite crystals from human articular cartilage. Osteoarthritis Cartilage 3:79–94

    Article  CAS  PubMed  Google Scholar 

  34. Simkin PA (2000) Friction and lubrication in synovial joints. J Rheumatol 27:567–568

    CAS  PubMed  Google Scholar 

  35. Stolz M, Gottardi R, Raiteri R et al (2009) Early detection of aging cartilage and osteoarthritis in mice and patient samples using atomic force microscopy. Nat Nanotechnol 4:186–192

    Article  CAS  PubMed  Google Scholar 

  36. Whitman, Walt (geb. 31.05.1819, gest. 26.03.1892): Sein poetisches Lebenswerk sind die „Grashalme“, erstmals 1855 erschienen. Die Übersetzung des Zitates entstammt „Walt Whitmans Werk“ (Rowohlt, Hamburg, 1956, S 130)

    Google Scholar 

  37. Wright V (1986) The rheology of joints. Br J Rheumatol 25:243–252

    Article  CAS  PubMed  Google Scholar 

  38. Yang L, van der Werf KO, Koopman BFJM et al (2007) Micromechanical bending of single collagen fibrils using atomic force microscopy. J Biomed Mater Res 82A:160–168

    Article  CAS  Google Scholar 

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Correspondence to Veit Krenn Prof. Dr. med. .

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Krenn, V., Mohr, W. (2016). Anatomie und Funktion. In: Amann, K., Kain, R., Klöppel, G. (eds) Pathologie. Pathologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-04566-0_27

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  • DOI: https://doi.org/10.1007/978-3-642-04566-0_27

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