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Invasive Karzinome

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Pathologie

Zusammenfassung

Das Kapitel behandelt systematisch, getrennt nach luminalem und basalem Phänotyp, alle beschriebenen und in den gebräuchlichen Klassifikationen aufgeführten invasiven Mammakarzinome. Die diagnostischen und differentialdiagnostischen Kriterien der einzelnen Karzinome werden systematisch in allen Aspekten dargestellt.

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Literatur

  1. Abati AD, Kimmel M, Rosen PP (1990) Apocrine mammary carcinoma. A clinicopathologic study of 72 cases. Am J Clin Pathol 94:371–377

    PubMed  CAS  Google Scholar 

  2. Aboumrad MH, Horn Jr RC, Fine G (1963) Lipid-secreting mammary carcinoma. Report of a case associated with Paget's disease of the nipple. Cancer 16:521–525

    PubMed  CAS  Google Scholar 

  3. Adami HO, Bergstrom R, Hansen J (1985) Age at first primary as a determinant of the incidence of bilateral breast cancer. Cumulative and relative risks in a population-based case-control study. Cancer 55:643–647

    PubMed  CAS  Google Scholar 

  4. Adeyinka A, Mertens F, Idvall I et al (1998) Cytogenetic findings in invasive breast carcinomas with prognostically favourable histology: a less complex karyotypic pattern? Int J Cancer 79:361–364

    PubMed  CAS  Google Scholar 

  5. Agnantis NT, Rosen PP (1979) Mammary carcinoma with osteoclast-like giant cells. A study of eight cases with follow-up data. Am J Clin Pathol 72:383–389

    PubMed  CAS  Google Scholar 

  6. Akhtar M, Robinson C, Ali MA et al (1983) Secretory carcinoma of the breast in adults. Light and electron microscopic study of three cases with review of the literature. Cancer 51:2245–2254

    PubMed  CAS  Google Scholar 

  7. Alva S, Shetty-Alva N (1999) An update of tumor metastasis to the breast data. Arch Surg 134:450

    PubMed  CAS  Google Scholar 

  8. Andersen JA (1974) Lobular carcinoma in situ. A long-term follow-up in 52 cases. Acta Pathol Microbiol Scand [A] 82:519–533

    CAS  Google Scholar 

  9. Anderson DE, Badzioch MD (1993) Familial effects of prostate and other cancers on lifetime breast cancer risk. Breast Cancer Res Treat 28:107–113

    PubMed  CAS  Google Scholar 

  10. Anderson TJ, Lamb J, Donnan P et al (1991) Comparative pathology of breast cancer in a randomised trial of screening. Br J Cancer 64:108–113

    PubMed  CAS  Google Scholar 

  11. Anderson WF, Pfeiffer RM, Dores GM et al (2006) Comparison of age distribution patterns for different histopathologic types of breast carcinoma. Cancer Epidemiol Biomarkers Prev 15:1899–1905

    PubMed  Google Scholar 

  12. Armes JE, Egan AJ, Southey MC et al (1998) The histologic phenotypes of breast carcinoma occurring before age 40 years in women with and without BRCA1 or BRCA2 germline mutations: a population-based study. Cancer 83:2335–2345

    PubMed  CAS  Google Scholar 

  13. Arora R, Robinson WA (1992) Breast metastases from malignant melanoma. J Surg Oncol 50:27–29

    PubMed  CAS  Google Scholar 

  14. Azoulay S, Lae M, Freneaux P et al (2005) KIT is highly expressed in adenoid cystic carcinoma of the breast, a basal-like carcinoma associated with a favorable outcome. Mod Pathol 18:1623–1631

    PubMed  CAS  Google Scholar 

  15. Azzopardi JG (1979) Apocrine carcinoma. In: Problems in breast pathology. W.B. Saunders, London, pp 341–345

    Google Scholar 

  16. Azzopardi JG, Eusebi V (1977) Melanocyte colonization and pigmentation of breast carcinoma. Histopathology 1:21–30

    PubMed  CAS  Google Scholar 

  17. Bailey MJ, Royce C, Sloane JP et al (1980) Bilateral carcinoma of the breast. Br J Surg 67:514–516

    PubMed  CAS  Google Scholar 

  18. Bane AL, Tjan S, Parkes RK et al (2005) Invasive lobular carcinoma: to grade or not to grade. Mod Pathol 18:621–628

    PubMed  Google Scholar 

  19. Bässler R (1997) Mamma. In: Remmele W (ed) Pathologie – Weibliches Genitale. Mamma, Pathologie der Schwangerschaft, der Plazenta und des Neugeborenen, Infektionskrankheiten des Fetus und des Neugeborenen, Tumoren des Kindesalters, Endokrine Organe. vol. 4. Springer, Berlin Heidelberg, pp 133–368

    Google Scholar 

  20. Bernstein JL, Thompson WD, Risch N et al (1992) The genetic epidemiology of second primary breast cancer. Am J Epidemiol 136:937–948

    PubMed  CAS  Google Scholar 

  21. Bernstein JL, Thompson WD, Risch N et al (1992) Risk factors predicting the incidence of second primary breast cancer among women diagnosed with a first primary breast cancer. Am J Epidemiol 136:925–936

    PubMed  CAS  Google Scholar 

  22. Berx G, Cleton-Jansen AM, Nollet F et al (1995) E-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers. EMBO J 14:6107–6115

    PubMed  CAS  Google Scholar 

  23. Bigotti G, Di-Giorgio CG (1986) Myoepithelioma of the breast: histologic, immunologic, and electromicroscopic appearance. J Surg Oncol 32:58–64

    PubMed  CAS  Google Scholar 

  24. Bloom HJ, Richardson WW, Field JR (1970) Host resistance and survival in carcinoma of breast: a study of 104 cases of medullary carcinoma in a series of 1,411 cases of breast cancer followed for 20 years. Br Med J 3:181–188

    PubMed  CAS  Google Scholar 

  25. Bogomoletz WV (1982) Pure squamous cell carcinoma of the breast. Arch Pathol Lab Med 106:57–59

    PubMed  CAS  Google Scholar 

  26. Borst MJ, Ingold JA (1993) Metastatic patterns of invasive lobular versus invasive ductal carcinoma of the breast. Surgery 114:637–641

    PubMed  CAS  Google Scholar 

  27. Botta G, Fessia L, Ghiringhello B (1982) Juvenile milk protein secreting carcinoma. Virchows Arch A Pathol Anat Histol 395:145–152

    PubMed  CAS  Google Scholar 

  28. Bussolati G, Papotti M, Sapino A et al (1987) Endocrine markers in argyrophilic carcinomas of the breast. Am J Surg Pathol 11:248–256

    PubMed  CAS  Google Scholar 

  29. Cardenosa G, Doudna C, Eklund GW (1994) Mucinous (colloid) breast cancer: clinical and mammographic findings in 10 patients. AJR Am J Roentgenol 162:1077–1079

    PubMed  CAS  Google Scholar 

  30. Carstens PH, Greenberg RA, Francis D et al (1985) Tubular carcinoma of the breast. A long term follow-up. Histopathology 9:271–280

    PubMed  CAS  Google Scholar 

  31. Carstens PH, Huvos AG, Foote Jr FW et al (1972) Tubular carcinoma of the breast: a clinicopathologic study of 35 cases. Am J Clin Pathol 58:231–238

    PubMed  CAS  Google Scholar 

  32. Chaignaud B, Hall TJ, Powers C et al (1994) Diagnosis and natural history of extramammary tumors metastatic to the breast. J Am Coll Surg 179:49–53

    PubMed  CAS  Google Scholar 

  33. Chang CK, Jacobs IA, Calilao G et al (2003) Metastatic infiltrating syringomatous adenoma of the breast. Arch Pathol Lab Med 127:e155–156

    PubMed  CAS  Google Scholar 

  34. Chaudary MA, Millis RR, Hoskins EO et al (1984) Bilateral primary breast cancer: a prospective study of disease incidence. Br J Surg 71:711–714

    PubMed  CAS  Google Scholar 

  35. Chen KT (1990) Pleomorphic adenoma of the breast. Am J Clin Pathol 93:792–794

    PubMed  CAS  Google Scholar 

  36. Chevallier B, Asselain B, Kunlin A et al (1987) Inflammatory breast cancer. Determination of prognostic factors by univariate and multivariate analysis. Cancer 60:897–902

    PubMed  CAS  Google Scholar 

  37. Chu PG, Weiss LM (2004) Immunohistochemical characterization of signet-ring cell carcinomas of the stomach, breast, and colon. Am J Clin Pathol 121:884–892

    PubMed  Google Scholar 

  38. Clayton F (1986) Pure mucinous carcinomas of breast: morphologic features and prognostic correlates. Hum Pathol 17:34–38

    PubMed  CAS  Google Scholar 

  39. Conant EF, Dillon RL, Palazzo J et al (1994) Imaging findings in mucin-containing carcinomas of the breast: correlation with pathologic features. AJR Am J Roentgenol 163:821–824

    PubMed  CAS  Google Scholar 

  40. Cooper HS, Patchefsky AS, Krall RA (1978) Tubular carcinoma of the breast. Cancer 42:2334–2342

    PubMed  CAS  Google Scholar 

  41. Coyne JD, Dervan PA (2002) Primary acinic cell carcinoma of the breast. J Clin Pathol 55:545–547

    PubMed  CAS  Google Scholar 

  42. Damiani S, Eusebi V, Losi L et al (1998) Oncocytic carcinoma (malignant oncocytoma) of the breast. Am J Surg Pathol 22:221–230

    PubMed  CAS  Google Scholar 

  43. Damiani S, Pasquinelli G, Lamovec J et al (2000) Acinic cell carcinoma of the breast: an immunohistochemical and ultrastructural study. Virchows Arch 437:74–81

    PubMed  CAS  Google Scholar 

  44. de Cremoux P, Salomon AV, Liva S et al (1999) p53 mutation as a genetic trait of typical medullary breast carcinoma. J Natl Cancer Inst 91:641–643

    PubMed  Google Scholar 

  45. de la Rochefordiere A, Asselain B, Scholl S et al (1994) Simultaneous bilateral breast carcinomas: a retrospective review of 149 cases. Int J Radiat Oncol Biol Phys 30:35–41

    PubMed  Google Scholar 

  46. De Leeuw WJ, Berx G, Vos CB et al (1997) Simultaneous loss of E-cadherin and catenins in invasive lobular breast cancer and lobular carcinoma in situ. J Pathol 183:404–411

    PubMed  Google Scholar 

  47. Deos PH, Norris HJ (1982) Well-differentiated (tubular) carcinoma of the breast. A clinicopathologic study of 145 pure and mixed cases. Am J Clin Pathol 78:1–7

    PubMed  CAS  Google Scholar 

  48. Di Tommaso L, Foschini MP, Ragazzini T et al (2004) Mucoepidermoid carcinoma of the breast. Virchows Arch 444:13–19

    PubMed  Google Scholar 

  49. Diab SG, Clark GM, Osborne CK et al (1999) Tumor characteristics and clinical outcome of tubular and mucinous breast carcinomas. J Clin Oncol 17:1442–1448

    PubMed  CAS  Google Scholar 

  50. DiCostanzo D, Rosen PP, Gareen I et al (1990) Prognosis in infiltrating lobular carcinoma. An analysis of "classical" and variant tumors. Am J Surg Pathol 14:12–23

    PubMed  CAS  Google Scholar 

  51. Dina R, Eusebi V (1997) Clear cell tumours of the breast. Semin Diagn Pathol 14:175–182

    PubMed  CAS  Google Scholar 

  52. Dixon JM, Anderson TJ, Page DL et al (1982) Infiltrating lobular carcinoma of the breast. Histopathology 6:149–161

    PubMed  CAS  Google Scholar 

  53. Dixon JM, Anderson TJ, Page DL et al (1983) Infiltrating lobular carcinoma of the breast: an evaluation of the incidence and consequence of bilateral disease. Br J Surg 70:513–516

    PubMed  CAS  Google Scholar 

  54. Domagala W, Harezga B, Szadowska A et al (1993) Nuclear p53 protein accumulates preferentially in medullary and high-grade ductal but rarely in lobular breast carcinomas. Am J Pathol 142:669–674

    PubMed  CAS  Google Scholar 

  55. Droufakou S, Deshmane V, Roylance R et al (2001) Multiple ways of silencing E-cadherin gene expression in lobular carcinoma of the breast. Int J Cancer 92:404–408

    PubMed  CAS  Google Scholar 

  56. Droulias CA, Sewell CW, McSweeney MB et al (1976) Inflammatory carcinoma of the breast: A correlation of clinical, radiologic and pathogic findings. Ann Surg 184:217–222

    PubMed  CAS  Google Scholar 

  57. du Toit RS, Locker AP, Ellis IO et al (1989) Invasive lobular carcinomas of the breast--the prognosis of histopathological subtypes. Br J Cancer 60:605–609

    PubMed  Google Scholar 

  58. Edge SBB, Compton CC, Fritz AG, Greene FL, Trotti A (2010) AJCC Cancer Staging Handbook. Springer, New York

    Google Scholar 

  59. Egan RL (1976) Bilateral breast carcinomas: Role of mammography. Cancer 38:931–938

    PubMed  CAS  Google Scholar 

  60. Ellis DL, Teitelbaum SL (1974) Inflammatory carcinoma of the breast. A pathologic definition. Cancer 33:1045–1047

    PubMed  CAS  Google Scholar 

  61. Ellis IO, Galea M, Broughton N et al (1992) Pathological prognostic factors in breast cancer. II. Histological type. Relationship with survival in a large study with long-term follow-up. Histopathology 20:479–489

    PubMed  CAS  Google Scholar 

  62. Ellis IO, Schnitt SJ, Sastre-Garau X et al. (2003) Invasive breast carcinoma. In: Tumours of the breast and female genital organs. IARC-Press, Lyon, pp 13–62

    Google Scholar 

  63. Ellis IO, Sastre-Garau X, Bussolati G et al (2003) Adenoid-cystic carcinoma. In: Tavassoli FA (ed) Pathology and genetics of tumors of the breast and female genital organs. IARC Press, Lyon, pp 44–45

    Google Scholar 

  64. Elson BC, Helvie MA, Frank TS et al (1993) Tubular carcinoma of the breast: mode of presentation, mammographic appearance, and frequency of nodal metastases. AJR Am J Roentgenol 161:1173–1176

    PubMed  CAS  Google Scholar 

  65. Eltorky M, Hall JC, Osborne PT et al (1994) Signet-ring cell variant of invasive lobular carcinoma of the breast. A clinicopathologic study of 11 cases. Arch Pathol Lab Med 118:245–248

    PubMed  CAS  Google Scholar 

  66. Enghardt MH, Hale JH (1989) An epithelial and spindle cell breast tumour of myoepithelial origin. An immunohistochemical and ultrastructural study. Virchows Arch A Pathol Anat Histopathol 416:177–184

    PubMed  CAS  Google Scholar 

  67. Erlandson RA (1989) Benign adenomyoepithelioma of the breast. Ultrastruct Pathol 13:307–314

    PubMed  CAS  Google Scholar 

  68. Esposito NN, Chivukula M, Dabbs DJ (2007) The ductal phenotypic expression of the E-cadherin/catenin complex in tubulolobular carcinoma of the breast: an immunohistochemical and clinicopathologic study. Mod Pathol 20:130–138

    PubMed  CAS  Google Scholar 

  69. Etzell JE, Devries S, Chew K et al (2001) Loss of chromosome 16q in lobular carcinoma in situ. Hum Pathol 32:292–296

    PubMed  CAS  Google Scholar 

  70. Eusebi V, Betts C, Haagensen DE et al (1984) Apocrine differentiation in lobular carcinoma of the breast: a morphologic, immunologic, and ultrastructural study. Hum Pathol 15:134–140

    PubMed  CAS  Google Scholar 

  71. Eusebi V, Foschini MP, Bussolati G et al (1995) Myoblastomatoid (histiocytoid) carcinoma of the breast. A type of apocrine carcinoma. Am J Surg Pathol 19:553–562

    PubMed  CAS  Google Scholar 

  72. Eusebi V, Lamovec J, Cattani MG et al (1986) Acantholytic variant of squamous-cell carcinoma of the breast. Am J Surg Pathol 10:855–861

    PubMed  CAS  Google Scholar 

  73. Eusebi V, Magalhaes F, Azzopardi JG (1992) Pleomorphic lobular carcinoma of the breast: an aggressive tumor showing apocrine differentiation. Hum Pathol 23:655–662

    PubMed  CAS  Google Scholar 

  74. Eusebi V, Millis RR, Cattani MG et al (1986) Apocrine carcinoma of the breast. A morphologic and immunocytochemical study. Am J Pathol 123:532–541

    PubMed  CAS  Google Scholar 

  75. Fastenberg NA, Martin RG, Buzdar AU et al (1985) Management of inflammatory carcinoma of the breast. A combined modality approach. Am J Clin Oncol 8:134–141

    PubMed  CAS  Google Scholar 

  76. Fechner RE (1975) Histologic variants of infiltrating lobular carcinoma of the breast. Hum Pathol 6:373–378

    PubMed  CAS  Google Scholar 

  77. Feyrter F, Hartmann G (1963) On the carcinoid growth form of the carcinoma mammae, especially the carcinoma solidum (gelatinosum) mammae. Frankf Z Pathol 73:24–39

    PubMed  CAS  Google Scholar 

  78. Fisher ER, Anderson S, Redmond C et al (1993) Pathologic findings from the National Surgical Adjuvant Breast Project protocol B-06. 10-year pathologic and clinical prognostic discriminants. Cancer 71:2507–2514

    PubMed  CAS  Google Scholar 

  79. Fisher ER, Fisher B, Sass R et al (1984) Pathologic findings from the National Surgical Adjuvant Breast Project (Protocol No. 4). XI. Bilateral breast cancer. Cancer 54:3002–3011

    PubMed  CAS  Google Scholar 

  80. Fisher ER, Gregorio R, Kim WS et al (1977) Lipid in invasive cancer of the breast. Am J Clin Pathol 68:558–561

    PubMed  CAS  Google Scholar 

  81. Fisher ER, Palekar AS, Redmond C et al (1980) Pathologic findings from the National Surgical Adjuvant Breast Project (protocol no. 4). VI. Invasive papillary cancer. Am J Clin Pathol 73:313–322

    PubMed  CAS  Google Scholar 

  82. Fisher ER, Tavares J, Bulatao IS et al (1985) Glycogen-rich, clear cell breast cancer: with comments concerning other clear cell variants. Hum Pathol 16:1085–1090

    PubMed  CAS  Google Scholar 

  83. Flagiello D, Gerbault-Seureau M, Sastre-Garau X et al (1998) Highly recurrent der(1;16)(q10;p10) and other 16q arm alterations in lobular breast cancer. Genes Chromosomes Cancer 23:300–306

    PubMed  CAS  Google Scholar 

  84. Foschini MP, Marucci G, Eusebi V (2002) Low-grade mucoepidermoid carcinoma of salivary glands: characteristic immunohistochemical profile and evidence of striated duct differentiation. Virchows Arch 440:536–542

    PubMed  CAS  Google Scholar 

  85. Fracchia AA, Robinson D, Legaspi A et al (1985) Survival in bilateral breast cancer. Cancer 55:1414–1421

    PubMed  CAS  Google Scholar 

  86. Fraser JL, Raza S, Chorny K et al (1998) Columnar alteration with prominent apical snouts and secretions: a spectrum of changes frequently present in breast biopsies performed for microcalcifications. Am J Surg Pathol 22:1521–1527

    PubMed  CAS  Google Scholar 

  87. Frolik D, Caduff R, Varga Z (2001) Pleomorphic lobular carcinoma of the breast: its cell kinetics, expression of oncogenes and tumour suppressor genes compared with invasive ductal carcinomas and classical infiltrating lobular carcinomas. Histopathology 39:503–513

    PubMed  CAS  Google Scholar 

  88. Frost AR, Terahata S, Yeh IT et al (1995) The significance of signet ring cells in infiltrating lobular carcinoma of the breast. Arch Pathol Lab Med 119:64–68

    PubMed  CAS  Google Scholar 

  89. Fujiwara M, Horiguchi M, Mori S et al (2005) Histiocytoid breast carcinoma: solid variant of invasive lobular carcinoma with decreased expression of both E-cadherin and CD44 epithelial variant. Pathol Int 55:353–359

    PubMed  Google Scholar 

  90. Gamel JW, Meyer JS, Feuer E et al (1996) The impact of stage and histology on the long-term clinical course of 163,808 patients with breast carcinoma. Cancer 77:1459–1464

    PubMed  CAS  Google Scholar 

  91. Georgiannos SN, Chin J, Goode AW et al (2001) Secondary neoplasms of the breast: a survey of the 20th Century. Cancer 92:2259–2266

    PubMed  CAS  Google Scholar 

  92. Goldstein NS, O'Malley BA (1997) Cancerization of small ectatic ducts of the breast by ductal carcinoma in situ cells with apocrine snouts: a lesion associated with tubular carcinoma. Am J Clin Pathol 107:561–566

    PubMed  CAS  Google Scholar 

  93. Graham MD, Yelland A, Peacock J et al (1993) Bilateral carcinoma of the breast. Eur J Surg Oncol 19:259–264

    PubMed  CAS  Google Scholar 

  94. Green I, McCormick B, Cranor M et al (1997) A comparative study of pure tubular and tubulolobular carcinoma of the breast. Am J Surg Pathol 21:653–657

    PubMed  CAS  Google Scholar 

  95. Guerin M, Gabillot M, Mathieu MC et al (1989) Structure and expression of c-erbB-2 and EGF receptor genes in inflammatory and non-inflammatory breast cancer: prognostic significance. Int J Cancer 43:201–208

    PubMed  CAS  Google Scholar 

  96. Gustafsson A, Tartter PI, Brower ST et al (1994) Prognosis of patients with bilateral carcinoma of the breast. J Am Coll Surg 178:111–116

    PubMed  CAS  Google Scholar 

  97. Haagensen CD (1971) Inflammatory carcinoma. In: Haagensen CD (ed) Diseases of the breast. WB Saunders, Philadelphia, pp 576–584

    Google Scholar 

  98. Hajdu SI, Urban JA (1972) Cancers metastatic to the breast. Cancer 29:1691–1696

    PubMed  CAS  Google Scholar 

  99. Harris M, Howell A, Chrissohou M et al (1984) A comparison of the metastatic pattern of infiltrating lobular carcinoma and infiltrating duct carcinoma of the breast. Br J Cancer 50:23–30

    PubMed  CAS  Google Scholar 

  100. Hawes D, Robinson R, Wira R (1991) Pseudomyxoma peritonei from metastatic colloid carcinoma of the breast. Gastrointest Radiol 16:80–82

    PubMed  CAS  Google Scholar 

  101. Hayes MM, Seidman JD, Ashton MA (1995) Glycogen-rich clear cell carcinoma of the breast. A clinicopathologic study of 21 cases. Am J Surg Pathol 19:904–911

    PubMed  CAS  Google Scholar 

  102. Healey EA, Cook EF, Orav EJ et al (1993) Contralateral breast cancer: clinical characteristics and impact on prognosis. J Clin Oncol 11:1545–1552

    PubMed  CAS  Google Scholar 

  103. Hilleren DJ, Andersson IT, Lindholm K et al (1991) Invasive lobular carcinoma: mammographic findings in a 10-year experience. Radiology 178:149–154

    PubMed  CAS  Google Scholar 

  104. Hirohashi S (1998) Inactivation of the E-cadherin-mediated cell adhesion system in human cancers. Am J Pathol 153:333–339

    PubMed  CAS  Google Scholar 

  105. Hislop TG, Elwood JM, Coldman AJ et al (1984) Second primary cancers of the breast: incidence and risk factors. Br J Cancer 49:79–85

    PubMed  CAS  Google Scholar 

  106. Holmberg L, Adami HO, Ekbom A et al (1988) Prognosis in bilateral breast cancer. Effects of time interval between first and second primary tumours. Br J Cancer 58:191–194

    PubMed  CAS  Google Scholar 

  107. Holst VA, Marshall CE, Moskaluk CA et al (1999) KIT protein expression and analysis of c-kit gene mutation in adenoid cystic carcinoma. Mod Pathol 12:956–960

    PubMed  CAS  Google Scholar 

  108. Horn PL, Thompson WD (1988) Risk of contralateral breast cancer. Associations with histologic, clinical, and therapeutic factors. Cancer 62:412–424

    PubMed  CAS  Google Scholar 

  109. Horsfall DJ, Tilley WD, Orell SR et al (1986) Relationship between ploidy and steroid hormone receptors in primary invasive breast cancer. Br J Cancer 53:23–28

    PubMed  CAS  Google Scholar 

  110. Iacocca MV, Maia DM (2001) Bilateral infiltrating lobular carcinoma of the breast with osteoclast-like giant cells. Breast J 7:60–65

    PubMed  CAS  Google Scholar 

  111. Jacquemier J, Padovani L, Rabayrol L et al (2005) Typical medullary breast carcinomas have a basal/myoepithelial phenotype. J Pathol 207:260–268

    PubMed  CAS  Google Scholar 

  112. Jain S, Fisher C, Smith P et al (1993) Patterns of metastatic breast cancer in relation to histological type. Eur J Cancer 29A:2155–2157

    PubMed  CAS  Google Scholar 

  113. Jennens RR, Rosenthal MA, Gonzales M (2004) Metastatic myoepithelioma of the breast. ANZ J Surg 74:1135–1137

    PubMed  Google Scholar 

  114. Jensen ML, Kiaer H, Melsen F (1996) Medullary breast carcinomas vs. poorly differentiated ductal carcinoma: an immunohistochemical study with keratin 19 and oestrogen receptor staining. Histopathology 29:241–245

    PubMed  CAS  Google Scholar 

  115. Jensen V, Jensen ML, Kiaer H et al (1997) MIB-1 expression in breast carcinomas with medullary features. An immunohistological study including correlations with p53 and bcl-2. Virchows Arch 431:125–130

    PubMed  CAS  Google Scholar 

  116. Jiao YF, Nakamura S, Oikawa T et al (2001) Sebaceous gland metaplasia in intraductal papilloma of the breast. Virchows Arch 438:505–508

    PubMed  CAS  Google Scholar 

  117. Kader HA, Jackson J, Mates D et al (2001) Tubular carcinoma of the breast: a population-based study of nodal metastases at presentation and of patterns of relapse. Breast J 7:8–13

    PubMed  CAS  Google Scholar 

  118. Kermarec J, Plouvier S, Duplay H et al (1973) Myoepithelial cell breast tumor. Ultrastructural study. Arch Anat Pathol Paris 21:225–231

    PubMed  CAS  Google Scholar 

  119. Kitchen PR, Smith TH, Henderson MA et al (2001) Tubular carcinoma of the breast: prognosis and response to adjuvant systemic therapy. ANZ J Surg 71:27–31

    PubMed  CAS  Google Scholar 

  120. Kollias J, Ellis IO, Elston CW et al (1999) Clinical and histological predictors of contralateral breast cancer. Eur J Surg Oncol 25:584–589

    PubMed  CAS  Google Scholar 

  121. Kollias J, Ellis IO, Elston CW et al (2001) Prognostic significance of synchronous and metachronous bilateral breast cancer. World J Surg 25:1117–1124

    PubMed  CAS  Google Scholar 

  122. Kollias J, Elston CW, Ellis IO et al (1997) Early-onset breast cancer--histopathological and prognostic considerations. Br J Cancer 75:1318–1323

    PubMed  CAS  Google Scholar 

  123. Komaki K, Sakamoto G, Sugano H et al (1988) Mucinous carcinoma of the breast in Japan. A prognostic analysis based on morphologic features. Cancer 61:989–996

    PubMed  CAS  Google Scholar 

  124. Krausz T, Jenkins D, Grontoft O et al (1989) Secretory carcinoma of the breast in adults: emphasis on late recurrence and metastasis. Histopathology 14:25–36

    PubMed  CAS  Google Scholar 

  125. Krishnan C, Longacre TA (2006) Ductal carcinoma in situ of the breast with osteoclast-like giant cells. Hum Pathol 37:369–372

    PubMed  CAS  Google Scholar 

  126. Kuroda H, Tamaru J, Takeuchi I et al (2006) Expression of E-cadherin, alpha-catenin, and beta-catenin in tubulolobular carcinoma of the breast. Virchows Arch 448:500–505

    PubMed  CAS  Google Scholar 

  127. Lamovec J, Bracko M (1994) Secretory carcinoma of the breast: light microscopical, immunohistochemical and flow cytometric study. Mod Pathol 7:475–479

    PubMed  CAS  Google Scholar 

  128. Lamovec JW, Jacqemier J (2003) Malignant lymphoma and metastatic tumours. In: Tavassoli FA (ed) Pathology and genetics of tumours of the breast and female genital organs. IARC Press, Lyon, pp 107–109

    Google Scholar 

  129. Lavasani MA, Moinfar F (2012) Molecular classification of breast carcinomas with particular emphasize on “basal-like” carcinoma: A critical review. J Biophotonics (Epub ahead of print)

    Google Scholar 

  130. Le Gal M, Ollivier L, Asselain B et al (1992) Mammographic features of 455 invasive lobular carcinomas. Radiology 185:705–708

    PubMed  Google Scholar 

  131. Leal C, Henrique R, Monteiro P et al (2001) Apocrine ductal carcinoma in situ of the breast: histologic classification and expression of biologic markers. Hum Pathol 32:487–493

    PubMed  CAS  Google Scholar 

  132. Lee JS, Kim YB, Min KW (2004) Metaplastic mammary carcinoma with osteoclast-like giant cells: identical point mutation of p53 gene only identified in both the intraductal and sarcomatous components. Virchows Arch 444:194–197

    PubMed  CAS  Google Scholar 

  133. Lee KC, Chan JK, Gwi E (1996) Tubular adenosis of the breast. A distinctive benign lesion mimicking invasive carcinoma. Am J Surg Pathol 20:46–54

    PubMed  CAS  Google Scholar 

  134. Lee SH, Park JM, Kook SH et al (2000) Metastatic tumors to the breast: mammographic and ultrasonographic findings. J Ultrasound Med 19:257–262

    PubMed  CAS  Google Scholar 

  135. Leibl S, Gogg-Kammerer M, Sommersacher A et al (2005) Metaplastic breast carcinomas: are they of myoepithelial differentiation? Immunohistochemical profile of the sarcomatoid subtype using novel myoepithelial markers. Am J Surg Pathol 29:347–353

    PubMed  Google Scholar 

  136. Lesser ML, Rosen PP, Kinne DW (1982) Multicentricity and bilaterality in invasive breast carcinoma. Surgery 91:234–240

    PubMed  CAS  Google Scholar 

  137. Levine PH, Steinhorn SC, Ries LG et al (1985) Inflammatory breast cancer: the experience of the surveillance, epidemiology, and end results (SEER) program. J Natl Cancer Inst 74:291–297

    PubMed  CAS  Google Scholar 

  138. Li CI, Uribe DJ, Daling JR (2005) Clinical characteristics of different histologic types of breast cancer. Br J Cancer 93:1046–1052

    PubMed  CAS  Google Scholar 

  139. Linell F, Ljungberg O, Andersson I (1980) Breast carcinoma. Aspects of early stages, progression and related problems. Acta Pathol Microbiol Scand Suppl: 1–233

    Google Scholar 

  140. Luna-More S, Gonzalez B, Acedo C et al (1994) Invasive micropapillary carcinoma of the breast. A new special type of invasive mammary carcinoma. Pathol Res Pract 190:668–674

    PubMed  CAS  Google Scholar 

  141. Maeno Y, Moroi S, Nagashima H et al (1999) alpha-catenin-deficient F9 cells differentiate into signet ring cells. Am J Pathol 154:1323–1328

    PubMed  CAS  Google Scholar 

  142. Maluf HM, Koerner FC (1994) Carcinomas of the breast with endocrine differentiation: a review. Virchows Arch 425:449–457

    PubMed  CAS  Google Scholar 

  143. Man S, Ellis IO, Sibbering M et al (1996) High levels of allele loss at the FHIT and ATM genes in non-comedo ductal carcinoma in situ and grade I tubular invasive breast cancers. Cancer Res 56:5484–5489

    PubMed  CAS  Google Scholar 

  144. Marchio C, Sapino A, Arisio R et al (2006) A new vision of tubular and tubulo-lobular carcinomas of the breast, as revealed by 3-D modelling. Histopathology 48:556–562

    PubMed  CAS  Google Scholar 

  145. Marcus JN, Watson P, Page DL et al (1996) Hereditary breast cancer: pathobiology, prognosis, and BRCA1 and BRCA2 gene linkage. Cancer 77:697–709

    PubMed  CAS  Google Scholar 

  146. Martinez A, Walker RA, Shaw JA et al (2001) Chromosome 3p allele loss in early invasive breast cancer: detailed mapping and association with clinicopathological features. Mol Pathol 54:300–306

    PubMed  CAS  Google Scholar 

  147. Mastropasqua MG, Maiorano E, Pruneri G et al (2005) Immunoreactivity for c-kit and p63 as an adjunct in the diagnosis of adenoid cystic carcinoma of the breast. Mod Pathol 18:1277–1282

    PubMed  CAS  Google Scholar 

  148. McBride CM, Hortobagyi GN (1985) Primary inflammatory carcinoma of the female breast: staging and treatment possibilities. Surgery 98:792–798

    PubMed  CAS  Google Scholar 

  149. McCulloch GL, Evans AJ, Yeoman L et al (1997) Radiological features of papillary carcinoma of the breast. Clin Radiol 52:865–868

    PubMed  CAS  Google Scholar 

  150. McDivitt RW, Boyce W, Gersell D (1982) Tubular carcinoma of the breast. Clinical and pathological observations concerning 135 cases. Am J Surg Pathol 6:401–411

    PubMed  CAS  Google Scholar 

  151. McDivitt RW, Stewart FW (1966) Breast carcinoma in children. JAMA 195:388–390

    PubMed  CAS  Google Scholar 

  152. Mechtersheimer G, Munk M, Barth T et al (1993) Expression of beta1 integrins in non-neoplastic mammary epithelium, fibroadenoma and carcinoma of the breast. Virchows ArchA 422:203–210

    CAS  Google Scholar 

  153. Miremadi A, Pinder SE, Lee AH et al (2002) Neuroendocrine differentiation and prognosis in breast adenocarcinoma. Histopathology 40:215–222

    PubMed  CAS  Google Scholar 

  154. Mitnick JS, Vazquez MF, Harris MN et al (1990) Invasive papillary carcinoma of the breast: mammographic appearance. Radiology 177:803–806

    PubMed  CAS  Google Scholar 

  155. Mitze M, Meyer F, Goepel E et al (1991) Special clinical and follow-up aspects of invasive lobular breast cancer. Geburtshilfe Frauenheilkd 51:973–979

    PubMed  CAS  Google Scholar 

  156. Moe RE, Anderson BO (2005) Distinctive biology of pleomorphic lobular carcinoma of the breast. J Surg Oncol 90:47–50

    PubMed  Google Scholar 

  157. Moinfar F (2007) Metaplastic carcinomas. In: Moinfar F (ed) Essentials of diagnostic breast pathology. Springer, Berlin Heidelberg New York, pp 234–237

    Google Scholar 

  158. Moinfar F (2007) Essentials of diagnostic breast pathology. Springer, Berlin Heidelberg New York

    Google Scholar 

  159. Moll R, Mitze M, Frixen UH et al (1993) Differential loss of E-cadherin expression in infiltrating ductal and lobular breast carcinomas. Am J Pathol 143:1731–1742

    PubMed  CAS  Google Scholar 

  160. Moore DH, Wilson DK, Hurteau JA et al (1998) Gynecologic cancers metastatic to the breast. J Am Coll Surg 187:178–181

    PubMed  CAS  Google Scholar 

  161. Mossler JA, Barton TK, Brinkhous AD et al (1980) Apocrine differentiation in human mammary carcinoma. Cancer 46:2463–2471

    PubMed  CAS  Google Scholar 

  162. Nassar H, Wallis T, Andea A et al (2001) Clinicopathologic analysis of invasive micropapillary differentiation in breast carcinoma. Mod Pathol 14:836–841

    PubMed  CAS  Google Scholar 

  163. Newstead GM, Baute PB, Toth HK (1992) Invasive lobular and ductal carcinoma: mammographic findings and stage at diagnosis. Radiology 184:623–627

    PubMed  CAS  Google Scholar 

  164. Nielsen M, Andersen JA, Henriksen FW et al (1981) Metastases to the breast from extramammary carcinomas. Acta Pathol Microbiol Scand [A] 89:251–256

    CAS  Google Scholar 

  165. Nishizaki T, Chew K, Chu L et al (1997) Genetic alterations in lobular breast cancer by comparative genomic hybridization. Int J Cancer 74:513–517

    PubMed  CAS  Google Scholar 

  166. Norris HJ, Taylor HB (1965) Prognosis of mucinous (gelatinous) carcinoma of the breast. Cancer 18:879–885

    PubMed  CAS  Google Scholar 

  167. O'Malley FP, Bane AL (2004) The spectrum of apocrine lesions of the breast. Adv Anat Pathol 11:1–9

    PubMed  Google Scholar 

  168. Oberman HA (1980) Secretory carcinoma of the breast in adults. Am J Surg Pathol 4:465–470

    PubMed  CAS  Google Scholar 

  169. Oberman HA, Fidler Jr. WJ (1979) Tubular carcinoma of the breast. Am J Surg Pathol 3:387–395

    PubMed  CAS  Google Scholar 

  170. Otterbach FK, Sheu SY, Schmitz K, Baba HA, Schmid KW (2005) C-kit overexpression in adenoid cystic breast carcinomas is not caused by mutations of the c-kit gene. Path Res Pract 201:217

    Google Scholar 

  171. Page DL, Dixon JM, Anderson TJ et al (1983) Invasive cribriform carcinoma of the breast. Histopathology 7:525–536

    PubMed  CAS  Google Scholar 

  172. Pantanowitz L, Harton A, Fraser JL (2001) Breast carcinoma with osteoclast-like giant cells. Breast J 7:199

    PubMed  CAS  Google Scholar 

  173. Papadatos G, Rangan AM, Psarianos T et al (2001) Probability of axillary node involvement in patients with tubular carcinoma of the breast. Br J Surg 88:860–864

    PubMed  CAS  Google Scholar 

  174. Parl FF, Richardson LD (1983) The histologic and biologic spectrum of tubular carcinoma of the breast. Hum Pathol 14:694–698

    PubMed  CAS  Google Scholar 

  175. Patchefsky AS, Shaber GS, Schwartz GF et al (1977) The pathology of breast cancer detected by mass population screening. Cancer 40:1659–1670

    PubMed  CAS  Google Scholar 

  176. Paterakos M, Watkin WG, Edgerton SM et al (1999) Invasive micropapillary carcinoma of the breast: a prognostic study. Hum Pathol 30:1459–1463

    PubMed  CAS  Google Scholar 

  177. Paterakos M, Watkin WG, Edgerton SM et al (1999) Invasive micropapillary carcinoma of the breast: a prognostic study. Hum Pathol 30:1459–1463

    PubMed  CAS  Google Scholar 

  178. Pedersen L, Zedeler K, Holck S et al (1995) Medullary carcinoma of the breast. Prevalence and prognostic importance of classical risk factors in breast cancer. Eur J Cancer 31A:2289–2295

    PubMed  CAS  Google Scholar 

  179. Perou CM, Sorlie T, Eisen MB et al (2000) Molecular portraits of human breast tumours. Nature 406:747–752

    PubMed  CAS  Google Scholar 

  180. Peters GN, Wolff M, Haagensen CD (1981) Tubular carcinoma of the breast. Clinical pathologic correlations based on 100 cases. Ann Surg 193:138–149

    PubMed  CAS  Google Scholar 

  181. Ponsky JL, Gliga L, Reynolds S (1984) Medullary carcinoma of the breast: an association with negative hormonal receptors. J Surg Oncol 25:76–78

    PubMed  CAS  Google Scholar 

  182. Porter PL, Garcia R, Moe R et al (1991) C-erbB-2 oncogene protein in in situ and invasive lobular breast neoplasia. Cancer 68:331–334

    PubMed  CAS  Google Scholar 

  183. Radhi JM (2000) Immunohistochemical analysis of pleomorphic lobular carcinoma: higher expression of p53 and chromogranin and lower expression of ER and PgR. Histopathology 36:156–160

    PubMed  CAS  Google Scholar 

  184. Rajakariar R, Walker RA (1995) Pathological and biological features of mammographically detected invasive breast carcinomas. Br J Cancer 71:150–154

    PubMed  CAS  Google Scholar 

  185. Rakha EA, El-Sayed ME, Menon S et al (2008) Histologic grading is an independent prognostic factor in invasive lobular carcinoma of the breast. Breast Cancer Res Treat 111:121–127

    PubMed  Google Scholar 

  186. Ramos CV, Taylor HB (1974) Lipid-rich carcinoma of the breast. A clinicopathologic analysis of 13 examples. Cancer 33:812–819

    PubMed  CAS  Google Scholar 

  187. Rapin V, Contesso G, Mouriesse H et al (1988) Medullary breast carcinoma. A reevaluation of 95 cases of breast cancer with inflammatory stroma. Cancer 61:2503–2510

    PubMed  CAS  Google Scholar 

  188. Rasmussen BB, Rose C, Thorpe SM et al (1985) Argyrophilic cells in 202 human mucinous breast carcinomas. Relation to histopathologic and clinical factors. Am J Clin Pathol 84:737–740

    PubMed  CAS  Google Scholar 

  189. Reale D, Guarino M, Bianchini E et al (1993) Infiltrating lobular carcinoma of the breast, alveolar variant, with stromal reactive osteoclast-like giant cells. Description of a case. Pathologica 85:525–532

    PubMed  CAS  Google Scholar 

  190. Reiner A, Reiner G, Spona J et al (1988) Histopathologic characterization of human breast cancer in correlation with estrogen receptor status. A comparison of immunocytochemical and biochemical analysis. Cancer 61:1149–1154

    PubMed  CAS  Google Scholar 

  191. Ridolfi RL, Rosen PP, Port A et al (1977) Medullary carcinoma of the breast: a clinicopathologic study with 10 year follow-up. Cancer 40:1365–1385

    PubMed  CAS  Google Scholar 

  192. Righi L, Sapino A, Marchio C et al (2010) Neuroendocrine differentiation in breast cancer: established facts and unresolved problems. Semin Diagn Pathol 27:69–76

    PubMed  Google Scholar 

  193. Rimm DL, Sinard JH, Morrow JS (1995) Reduced alpha-catenin and E-cadherin expression in breast cancer. Lab Invest 72:506–512

    PubMed  CAS  Google Scholar 

  194. Ro JY, Silva EG, Gallager HS (1987) Adenoid cystic carcinoma of the breast. Hum Pathol 18:1276–1281

    PubMed  CAS  Google Scholar 

  195. Robbins GF, Berg JW (1964) Bilateral primary breast cancer; a prospective clinicopathological study. Cancer 17:1501–1527

    PubMed  CAS  Google Scholar 

  196. Robbins GF, Shah J, Rosen P et al (1974) Inflammatory carcinoma of the breast. Surg Clin North Am 54:801–810

    PubMed  CAS  Google Scholar 

  197. Roncaroli F, Lamovec J, Zidar A et al (1996) Acinic cell-like carcinoma of the breast. Virchows Arch 429:69–74

    PubMed  CAS  Google Scholar 

  198. Rosen PP (1986) Mucocele-like tumors of the breast. Am J Surg Pathol 10:464–469

    PubMed  CAS  Google Scholar 

  199. Rosen PP (1987) Adenomyoepithelioma of the breast. Hum Pathol 18:1232–1237

    PubMed  CAS  Google Scholar 

  200. Rosen PP (2001) Mammary carcinoma with osteoclast-like giant cells. In: Rosen PP (ed) Rosen's breast pathology. Lippincott Williams and Wilkins, Philadelphia, pp 517–526

    Google Scholar 

  201. Rosen PP (2001) Rosen's breast pathology. Lippincott Williams & Wilkins, Philadelphia

    Google Scholar 

  202. Rosen PP, Cranor ML (1991) Secretory carcinoma of the breast. Arch Pathol Lab Med 115:141–144

    PubMed  CAS  Google Scholar 

  203. Rosen PP, Ernsberger D (1987) Low-grade adenosquamous carcinoma. A variant of metaplastic mammary carcinoma. Am J Surg Pathol 11:351–358

    PubMed  CAS  Google Scholar 

  204. Rosen PP, Lesser ML, Arroyo CD et al (1995) Immunohistochemical detection of HER2/neu in patients with axillary lymph node negative breast carcinoma. A study of epidemiologic risk factors, histologic features, and prognosis. Cancer 75:1320–1326

    PubMed  CAS  Google Scholar 

  205. Rosen PP, Oberman HA (1992) Atlas of tumor pathology. Tumors of the mammary gland. Armed Forces Institute of Pathology, Washington, D.C.

    Google Scholar 

  206. Rosen PP, Scott M (1984) Cystic hypersecretory duct carcinoma of the breast. Am J Surg Pathol 8:31–41

    PubMed  CAS  Google Scholar 

  207. Roylance R, Gorman P, Harris W et al (1999) Comparative genomic hybridization of breast tumors stratified by histological grade reveals new insights into the biological progression of breast cancer. Cancer Res 59:1433–1436

    PubMed  CAS  Google Scholar 

  208. Rozan S, Vincent SA, Zafrani B et al (1998) No significant predictive value of c-erbB-2 or p53 expression regarding sensitivity to primary chemotherapy or radiotherapy in breast cancer. Int J Cancer 79:27–33

    PubMed  CAS  Google Scholar 

  209. Ruiz-Sauri A, Almenar-Medina S, Callaghan RC et al (1995) Radial scar versus tubular carcinoma of the breast. A comparative study with quantitative techniques (morphometry, image- and flow cytometry. Pathol Res Pract 191:547–554

    PubMed  CAS  Google Scholar 

  210. Saltzstein SL (1974) Clinically occult inflammatory carcinoma of the breast. Cancer 34:382–388

    PubMed  CAS  Google Scholar 

  211. Sapino A, Bussolati G (2002) Is detection of endocrine cells in breast adenocarcinoma of diagnostic and clinical significance? Histopathology 40:211–214

    PubMed  CAS  Google Scholar 

  212. Sapino A, Frigerio A, Peterse JL et al (2000) Mammographically detected in situ lobular carcinomas of the breast. Virchows Arch 436:421–430

    PubMed  CAS  Google Scholar 

  213. Sapino A, Righi L, Cassoni P et al (2001) Expression of apocrine differentiation markers in neuroendocrine breast carcinomas of aged women. Mod Pathol 14:768–776

    PubMed  CAS  Google Scholar 

  214. Sastre-Garau X, Jouve M, Asselain B et al (1996) Infiltrating lobular carcinoma of the breast. Clinicopathologic analysis of 975 cases with reference to data on conservative therapy and metastatic patterns. Cancer 77:113–120

    PubMed  CAS  Google Scholar 

  215. Schell SR, Montague ED, Spanos Jr WJ et al (1982) Bilateral breast cancer in patients with initial stage I and II disease. Cancer 50:1191–1194

    PubMed  CAS  Google Scholar 

  216. Schmitt FC, Ribeiro CA, Alvarenga S et al (2000) Primary acinic cell-like carcinoma of the breast--a variant with good prognosis? Histopathology 36:286–289

    PubMed  CAS  Google Scholar 

  217. Schneider JA (1989) Invasive papillary breast carcinoma: mammographic and sonographic appearance. Radiology 171:377–379

    PubMed  CAS  Google Scholar 

  218. Schnitt SJ, Collins LC (2009) Biopsy interpretation of the breast. Lippincott Williams & Wilkins, Philadelphia, PA

    Google Scholar 

  219. Schurch W, Potvin C, Seemayer TA (1985) Malignant myoepithelioma (myoepithelial carcinoma) of the breast: an ultrastructural and immunocytochemical study. UltrastructPathol 8:1–11

    PubMed  CAS  Google Scholar 

  220. Scopsi L, Andreola S, Pilotti S et al (1994) Mucinous carcinoma of the breast. A clinicopathologic, histochemical, and immunocytochemical study with special reference to neuroendocrine differentiation. Am J Surg Pathol 18:702–711

    PubMed  CAS  Google Scholar 

  221. Shabb NS, Tawil A, Mufarrij A et al (1997) Mammary carcinoma with osteoclastlike giant cells cytologically mimicking benign breast disease. A case report. Acta Cytol 41:1284–1288

    PubMed  CAS  Google Scholar 

  222. Shin SJ, Rosen PP (2002) Solid variant of mammary adenoid cystic carcinoma with basaloid features: a study of nine cases. Am J Surg Pathol 26:413–420

    PubMed  Google Scholar 

  223. Shousha S, Backhous CM, Alaghband-Zadeh J et al (1986) Alveolar variant of invasive lobular carcinoma of the breast. A tumor rich in estrogen receptors. Am J Clin Pathol 85:1–5

    PubMed  CAS  Google Scholar 

  224. Shousha S, Coady AT, Stamp T et al (1989) Oestrogen receptors in mucinous carcinoma of the breast: an immunohistological study using paraffin wax sections. J Clin Pathol 42:902–905

    PubMed  CAS  Google Scholar 

  225. Shousha S, Schoenfeld A, Moss J et al (1994) Light and electron microscopic study of an invasive cribriform carcinoma with extensive microcalcification developing in a breast with silicone augmentation. Ultrastruct Pathol 18:519–523

    PubMed  CAS  Google Scholar 

  226. Silverstein MJ, Lewinsky BS, Waisman JR et al (1994) Infiltrating lobular carcinoma. Is it different from infiltrating duct carcinoma. Cancer 73:1673–1677

    PubMed  CAS  Google Scholar 

  227. Siriaunkgul S, Tavassoli FA (1993) Invasive micropapillary carcinoma of the breast. Mod Pathol 6:660–662

    PubMed  CAS  Google Scholar 

  228. Soares J, Tomasic G, Bucciarelli E et al (1994) Intralobular growth of myoepithelial cell carcinoma of the breast. Virchows Arch 425:205–210

    PubMed  CAS  Google Scholar 

  229. Somerville JE, Clarke LA, Biggart JD (1992) c-erbB-2 overexpression and histological type of in situ and invasive breast carcinoma. J Clin Pathol 45:16–20

    PubMed  CAS  Google Scholar 

  230. Soomro S, Shousha S, Taylor P et al (1991) c-erbB-2 expression in different histological types of invasive breast carcinoma. J Clin Pathol 44:211–214

    PubMed  CAS  Google Scholar 

  231. Sorensen FB, Paulsen SM (1987) Glycogen-rich clear cell carcinoma of the breast: a solid variant with mucus. A light microscopic, immunohistochemical and ultrastructural study of a case. Histopathology 11:857–869

    PubMed  CAS  Google Scholar 

  232. Sorlie T, Perou CM, Tibshirani R et al (2001) Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A 98:10869–10874

    PubMed  CAS  Google Scholar 

  233. Stocks LH, Patterson FM (1976) Inflammatory carcinoma of the breast. Surg Gynecol Obstet 143:885–889

    PubMed  CAS  Google Scholar 

  234. Storm HH, Jensen OM (1986) Risk of contralateral breast cancer in Denmark. Br J Cancer 54:483–492

    PubMed  CAS  Google Scholar 

  235. Stutz JA, Evans AJ, Pinder S et al (1994) The radiological appearances of invasive cribriform carcinoma of the breast. Nottingham Breast Team. Clin Radiol 49:693–695

    PubMed  CAS  Google Scholar 

  236. Suster S, Moran CA, Hurt MA (1991) Syringomatous squamous tumors of the breast. Cancer 67:2350–2355

    PubMed  CAS  Google Scholar 

  237. Tamai M (1992) Intraductal growth of malignant mammary myoepithelioma. AmJ Surg Pathol 16:1116–1125

    PubMed  CAS  Google Scholar 

  238. Tamai M, Nomura K, Hiyama H (1994) Aspiration cytology of malignant intraductal myoepithelioma of the breast. A case report. Acta Cytol 38:435–440

    PubMed  CAS  Google Scholar 

  239. Tavassoli FA (1992) Classification of metaplastic carcinomas of the breast. Pathol Annu 27(2):89–119

    PubMed  Google Scholar 

  240. Tavassoli FA (1999) Pathology of the breast. Appleton and Lange, Norwalk

    Google Scholar 

  241. Tavassoli FA, Devilee P (eds) (2003) Tumours of the breast and female genital organs. IARC Press, Lyon

    Google Scholar 

  242. Tavassoli FA, Devilee P (2003) WHO Classification of Tumours. In: Tumours of the breast and female genital organs. IARC Press, Lyon

    Google Scholar 

  243. Tavassoli FA, Norris HJ (1980) Secretory carcinoma of the breast. Cancer 45:2404–2413

    PubMed  CAS  Google Scholar 

  244. Tavassoli FA, Norris HJ (1986) Breast carcinoma with osteoclastlike giant cells. Arch Pathol Lab Med 110:636–639

    PubMed  CAS  Google Scholar 

  245. Tavassoli FA, Norris HJ (1986) Mammary adenoid cystic carcinoma with sebaceous differentiation. A morphologic study of the cell types. Arch Pathol Lab Med 110:1045–1053

    PubMed  CAS  Google Scholar 

  246. Tavassoli FA, Norris HJ (1994) Intraductal apocrine carcinoma: a clinicopathologic study of 37 cases. Mod Pathol 7:813–818

    PubMed  CAS  Google Scholar 

  247. Thorner PS, Kahn HJ, Baumal R et al (1986) Malignant myoepithelioma of the breast. An immunohistochemical study by light and electron microscopy. Cancer 57:745–750

    PubMed  CAS  Google Scholar 

  248. Toikkanen S, Kujari H (1989) Pure and mixed mucinous carcinomas of the breast: a clinicopathologic analysis of 61 cases with long-term follow-up. Hum Pathol 20:758–764

    PubMed  CAS  Google Scholar 

  249. Toikkanen S, Pylkkanen L, Joensuu H (1997) Invasive lobular carcinoma of the breast has better short- and long-term survival than invasive ductal carcinoma. Br J Cancer 76:1234–1240

    PubMed  CAS  Google Scholar 

  250. Towfighi J, Simmonds MA, Davidson EA (1983) Mucin and fat emboli in mucinous carcinomas. Cause of hemorrhagic cerebral infarcts. Arch Pathol Lab Med 107:646–649

    PubMed  CAS  Google Scholar 

  251. Trendell-Smith NJ, Peston D, Shousha S (1999) Adenoid cystic carcinoma of the breast: a tumour commonly devoid of oestrogen receptors and related proteins. Histopathology 35:241–248

    PubMed  CAS  Google Scholar 

  252. UICC (2002) TNM classification of malignant tumors. John Wiley & Sons, New York

    Google Scholar 

  253. Van-Hoeven KH, Drudis T, Cranor ML et al (1993) Low-grade adenosquamous carcinoma of the breast. A clinocopathologic study of 32 cases with ultrastructural analysis. AmJ Surg Pathol 17:248–258

    PubMed  CAS  Google Scholar 

  254. van Bogaert LJ, Maldague P (1977) Histologic variants of lipid-secreting carcinoma of the breast. Virchows Arch A Pathol Anat Histol 375:345–353

    PubMed  Google Scholar 

  255. Venable JG, Schwartz AM, Silverberg SG (1990) Infiltrating cribriform carcinoma of the breast: a distinctive clinicopathologic entity. Hum Pathol 21:333–338

    PubMed  CAS  Google Scholar 

  256. Vergier B, Trojani M, de Mascarel I et al (1991) Metastases to the breast: differential diagnosis from primary breast carcinoma. J Surg Oncol 48:112–116

    PubMed  CAS  Google Scholar 

  257. Vizcaino I, Torregrosa A, Higueras V et al (2001) Metastasis to the breast from extramammary malignancies: a report of four cases and a review of literature. Eur Radiol 11:1659–1665

    PubMed  CAS  Google Scholar 

  258. Vos CB, Cleton-Jansen AM, Berx G et al (1997) E-cadherin inactivation in lobular carcinoma in situ of the breast: an early event in tumorigenesis. Br J Cancer 76:1131–1133

    PubMed  CAS  Google Scholar 

  259. Waldman FM, Hwang ES, Etzell J et al (2001) Genomic alterations in tubular breast carcinomas. Hum Pathol 32:222–226

    PubMed  CAS  Google Scholar 

  260. Walsh MM, Bleiweiss IJ (2001) Invasive micropapillary carcinoma of the breast: eighty cases of an underrecognized entity. Hum Pathol 32:583–589

    PubMed  CAS  Google Scholar 

  261. Wargotz ES, Norris HJ (1989) Metaplastic carcinomas of the breast. I. Matrix-producing carcinoma. Hum Pathol 20:628–635

    PubMed  CAS  Google Scholar 

  262. Wargotz ES, Norris HJ (1990) Metaplastic carcinomas of the breast. IV. Squamous cell carcinoma of ductal origin. Cancer 65:272–276

    PubMed  CAS  Google Scholar 

  263. Wargotz ES, Norris HJ (1990) Metaplastic carcinomas of the breast: V. Metaplastic carcinoma with osteoclastic giant cells. Hum Pathol 21:1142–1150

    PubMed  CAS  Google Scholar 

  264. Wargotz ES, Silverberg SG (1988) Medullary carcinoma of the breast: a clinicopathologic study with appraisal of current diagnostic criteria. Hum Pathol 19:1340–1346

    PubMed  CAS  Google Scholar 

  265. Wheeler DT, Tai LH, Bratthauer GL et al (2004) Tubulolobular carcinoma of the breast: an analysis of 27 cases of a tumor with a hybrid morphology and immunoprofile. Am J Surg Pathol 28:1587–1593

    PubMed  Google Scholar 

  266. Wick MR, Lillemoe TJ, Copland GT et al (1989) Gross cystic disease fluid protein-15 as a marker for breast cancer: immunohistochemical analysis of 690 human neoplasms and comparison with alpha-lactabulmin. Hum Pathol 20:281–287

    PubMed  CAS  Google Scholar 

  267. Williams SA, Ehlers 2nd RA, Hunt KK et al (2007) Metastases to the breast from nonbreast solid neoplasms: Presentation and determinants of survival. Cancer 110:7371–737

    Google Scholar 

  268. Wilson TE, Helvie MA, Oberman HA et al (1995) Pure and mixed mucinous carcinoma of the breast: pathologic basis for differences in mammographic appearance. AJR Am J Roentgenol 165:285–289

    PubMed  CAS  Google Scholar 

  269. Winchester DJ, Chang HR, Graves TA et al (1998) A comparative analysis of lobular and ductal carcinoma of the breast: presentation, treatment, and outcomes. J Am Coll Surg 186:416–422

    PubMed  CAS  Google Scholar 

  270. Wrba F, Ellinger A, Reiner G et al (1988) Ultrastructural and immunohistochemical characteristics of lipid-rich carcinoma of the breast. Virchows Arch A Pathol Anat Histopathol 413:381–385

    PubMed  CAS  Google Scholar 

  271. Zafrani B, Aubriot MH, Mouret E et al (2000) High sensitivity and specificity of immunohistochemistry for the detection of hormone receptors in breast carcinoma: comparison with biochemical determination in a prospective study of 793 cases. Histopathology 37:536–545

    PubMed  CAS  Google Scholar 

  272. Zekioglu O, Erhan Y, Ciris M et al (2004) Invasive micropapillary carcinoma of the breast: high incidence of lymph node metastasis with extranodal extension and its immunohistochemical profile compared with invasive ductal carcinoma. Histopathology 44:18–23

    PubMed  CAS  Google Scholar 

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Böcker, W., Otterbach, F., Sinn, HP., Decker, T. (2013). Invasive Karzinome. In: Klöppel, G., Kreipe, H., Remmele, W., Dietel, M. (eds) Pathologie. Pathologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-04564-6_7

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