Zusammenfassung
Das Kapitel behandelt die Pankreatitis, unterteilt in akute und chronische Pankreatitis. Die Pathologie wird ergänzt durch die Besprechung der Ätiologie, Pathogenese, Epidemiologie und Klinik. Die akute wie die chronische Pankreatitis werden in Subtypen wie die alkoholische, hereditäre, tropische, autoimmune und obstruktive Pankreatitis unterteilt. Ausgewähltes Bildmaterial erleichtert die Diagnostik und das Verständnis.
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Literatur
Abraham SC, Cruz-Correa M, Argani P, Furth EE, Hruban RH, Boitnott JK (2003) Lymphoplasmacytic chronic cholecystitis and biliary tract disease in patients with lymphoplasmacytic sclerosing pancreatitis. Am J Surg Pathol 27:441–451
Abraham SC, Leach S, Yeo CJ, Cameron JL, Murakata LA, Boitnott JK, Albores-Saavedra J, Hruban RH (2003) Eosinophilic pancreatitis and increased eosinophils in the pancreas. Am J Surg Pathol 27:334–342
Adsay NV, Zamboni G (2004) Paraduodenal pancreatitis: A clinico-pathologically distinct entity unifying “cystic dystrophy of heterotopic pancreas,” “para-duodenal wall cyst,” and “groove pancreatitis”. Semin Diagn Pathol 21:247–254
Ammann RW, Akovbiantz A, Largiader F, Schueler G (1984) Course and outcome of chronic pancreatitis. Longitudinal study of a mixed medical-surgical series of 245 patients. Gastroenterology 86:820–828
Ammann RW, Heitz PU, Klöppel G (1996) Course of alcoholic chronic pancreatitis: a prospective clinicomorphological long-term study. Gastroenterology 111:224–231
Ammann RW, Muench R, Otto R, Buehler H, Freiburghaus AU, Siegenthaler W (1988) Evolution and regression of pancreatic calcification in chronic pancreatitis. A prospective long-term study of 107 patients. Gastroenterology 95:1018–1028
Augarten A, Ben Tov A, Madgar I, Barak A, Akons H, Laufer J, Efrati O, Aviram M, Bentur L, Blau H, Paret G, Wilschanski M, Kerem BS, Yahav Y (2008) The changing face of the exocrine pancreas in cystic fibrosis: the correlation between pancreatic status, pancreatitis and cystic fibrosis genotype. Eur J Gastroenterol Hepatol 20:164–168
Banerjee AK, Patel KJ, Grainger SL (1989) Drug-induced acute pancreatitis. A critical review. Med Toxicol Adverse Drug Exp 4:186–198
Banks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, Tsiotos GG, Vege SS (2013) Classification of acute pancreatitis – 2012: revision of the Atlanta classification and definitions by international consensus. Gut 62:102–111
Bartholomew C (1970) Acute scorpion pancreatitis in Trinidad. Br Med J 1:666–668
Bastid C, Sahel J, Choux R, Payan MJ, Sarles H (1990) Eosinophilic pancreatitis: report of a case. Pancreas 5:104–107
Becker V (1981) Acute pancreatitis: pathological anatomy and pathogenesis. World J Surg 5:303–313
Becker V, Doerr W, Seifert G, Uehlinger E (1973) Bauchspeicheldrüse (Inselapparat ausgenommen). Springer, Berlin
Bedossa P, Bacci J, Lemaigre G, Martin E (1990) Lymphocyte subsets and HLA-DR expression in normal pancreas and chronic pancreatitis. Pancreas 5:415–420
Bockman DE, Büchler M, Malfertheiner P, Beger HG (1988) Analysis of nerves in chronic pancreatitis. Gastroenterology 94:1459–1469
Bradley EL, Gonzalez AC, Clements JL Jr. (1976) Acute pancreatic pseudocysts: incidence and implications. Ann Surg 184:734–737
Bradley EL (1994) The necessity for a clinical classification of acute pancreatitis: the Atlanta system. In: Bradley EL (Hrsg) Acute pancreatitis. Diagnosis and therapy. Raven Press, New York, S 27–32
Brünner H, Rothmund M (1973) Primärer Hyperparathyreoidismus, Pankreatitis und Cholelithiasis. Dtsch Med Wochenschr 98:426–429
Büchler M, Weihe D, Friess H, Malfertheiner P, Bockman E, Müller S, Nohr D, Beger HG (1992) Changes in peptidergic innervation in chronic pancreatitis. Pancreas 7:183–192
Büchler MW, Martignoni ME, Friess H, Malfertheiner P (2009) A proposal for a new clinical classification of chronic pancreatitis. BMC Gastroenterol 9:93
Buntain WL, Wood JB, Woolley MM (1978) Pancreatitis in childhood. J Pediatr Surg 13:143–149
Buter A, Imrie CW, Carter CR, Evans S, McKay CJ (2002) Dynamic nature of early organ dysfunction determines outcome in acute pancreatitis. Br J Surg 89:298–302
Casetti L, Bassi C, Salvia R, Butturini G, Graziani R, Falconi M, Frulloni L, Crippa S, Zamboni G, Pederzoli P (2009) “Paraduodenal” pancreatitis: results of surgery on 58 consecutives patients from a single institution. World J Surg 33:2664–2669
Cay A, Imamoglu M, Cobanoglu U (2006) Eosinophilic pancreatitis mimicking pancreatic neoplasia. Can J Gastroenterol 20:361–364
Chari ST, Klöppel G, Zhang L, Notohara K, Lerch MM, Shimosegawa T (2010) Histopathologic and clinical subtypes of autoimmune pancreatitis: the Honolulu consensus document. Pancreas 39:549–554
Chaun H, King DM, Gofton JP, Sutherland WH, Bogoch A (1972) Sarcoidosis of the pancreas. Dig Dis Sci 17:725–730
Chen JM, Ferec C (2012) Genetics and pathogenesis of chronic pancreatitis: the 2012 update. Clin Res Hepatol Gastroenterol 36:334–340
Chiba K, Kamisawa T, Kuruma S, Iwasaki S, Tabata T, Koizumi S, Endo Y, Kuwata G, Fujiwara T, Arakawa T, Koizumi K, Momma K (2014) Major and minor duodenal papillae in autoimmune pancreatitis. Pancreas 43:1299–1302
Cho JH, Kim TN, Kim SB (2015) Comparison of clinical course and outcome of acute pancreatitis according to the two main etiologies: alcohol and gallstone. BMC Gastroenterol 15:87
Creutzfeldt W, Schmidt H (1976) Etiology and pathogenesis of pancreatitis. In: Bockus HL (Hrsg) Gastroenterology, 3. Aufl. Saunders, Philadelphia, S 1005–1019
Dammann HG (1981) Akute hämorrhagisch-nekrotisierende Pankreatitis. Med Klin 76:186–189
Derikx MH, Kovacs P, Scholz M, Masson E, Chen JM, Ruffert C, Lichtner P, Te Morsche RH, Cavestro GM, Ferec C, Drenth JP, Witt H, Rosendahl J (2015) Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study. Gut 64:1426–1433
Deshpande V, Chicano S, Finkelberg D, Selig MK, Mino-Kenudson M, Brugge WR, Colvin RB, Lauwers GY (2006) Autoimmune pancreatitis: a systemic immune complex mediated disease. Am J Surg Pathol 30:1537–1545
Deshpande V, Zen Y, Chan JK, Yi EE, Sato Y, Yoshino T, Klöppel G, Heathcote JG, Khosroshahi A, Ferry JA, Aalberse RC, Bloch DB, Brugge WR, Bateman AC, Carruthers MN, Chari ST, Cheuk W, Cornell LD, Fernandez-Del Castillo C, Forcione DG, Hamilos DL, Kamisawa T, Kasashima S, Kawa S, Kawano M, Lauwers GY, Masaki Y, Nakanuma Y, Notohara K, Okazaki K, Ryu JK, Saeki T, Sahani DV, Smyrk TC, Stone JR, Takahira M, Webster GJ, Yamamoto M, Zamboni G, Umehara H, Stone JH (2012) Consensus statement on the pathology of IgG4-related disease. Mod Pathol 25:1181–1192
Detlefsen S, Bräsen JH, Zamboni G, Capelli P, Klöppel G (2010) Deposition of complement C3c, immunoglobulin (Ig)G4 and IgG at the basement membrane of pancreatic ducts and acini in autoimmune pancreatitis. Histopathology 57:825–835
Detlefsen S, Klöppel G (2016) Histopathology of IgG4-related disease. Z Rheumatol 75:666–674
Detlefsen S, Klöppel G (2018) IgG4-related disease: with emphasis on the biopsy diagnosis of autoimmune pancreatitis and sclerosing cholangitis. Virchows Arch 472:545–556
Detlefsen S, Mohr Drewes A, Vyberg M, Klöppel G (2009) Diagnosis of autoimmune pancreatitis by core needle biopsy: application of six microscopic criteria. Virchows Arch 454:531–539
Detlefsen S, Sipos B, Feyerabend B, Klöppel G (2005) Pancreatic fibrosis associated with age and ductal papillary hyperplasia. Virchows Arch 447:800–805
Detlefsen S, Sipos B, Feyerabend B, Klöppel G (2006) Fibrogenesis in alcoholic chronic pancreatitis: the role of tissue necrosis, macrophages, myofibroblasts and cytokines. Mod Pathol 19:1019–1026
Detlefsen S, Sipos B, Zhao J, Drewes AM, Klöppel G (2008) Autoimmune pancreatitis: expression and cellular source of profibrotic cytokines and their receptors. Am J Surg Pathol 32:968–995
Detlefsen S, Zamboni G, Frulloni L, Feyerabend B, Braun F, Gerke O, Schlitter AM, Esposito I, Klöppel G (2012) Clinical features and relapse rates after surgery in type 1 autoimmune pancreatitis differ from type 2: a study of 114 surgically treated European patients. Pancreatology 12:276–283
Esposito I, Bergmann F, Penzel R, di Mola FF, Shrikhande S, Büchler MW, Friess H, Otto HF (2004) Oligoclonal T-cell populations in an inflamatory pseudotumor of the pancreas possibly related to autoimmune pancreatitis: an immunohistochemical and molecular analysis. Virchows Arch 444:119–126
Eugene C, Gury B, Bergue A, Quevauvilliers J (1984) Ictère révélant une atteinte pancréatique au cours d’un syndrome hyperéosinophilique idiopathique. Gastroenterol Clin Biol 8:966–969
Euscher E, Vaswani K, Frankel W (2000) Eosinophilic pancreatitis: a rare entity that can mimic a pancreatic neoplasm. Ann Diagn Pathol 4:379–385
Fléjou JF, Potet F, Bernades P (1989) La pancréatite à éosinophiles: une manifestation rare de l’allergie digestive? Gastroenterol Clin Biol 13:731–733
Fléjou JF, Potet F, Molas G, Bernades P, Amouyal P, Fékété F (1993) Cystic dystrophy of the gastric and duodenal wall developing in heterotopic pancreas: an unrecognized entity. Gut 34:343–347
Foulis AK (1980) Histological evidence of initiating factors in acute necrotising pancreatitis in man. J Clin Pathol 33:1125–1131
Foulis AK, Farquharson MA, Sale GE (1989) The pancreas in acute graft versus host disease in man. Histopathology 14:121–128
Geetha M, Saumya M, Balakrishnan V (2012) Spectrum of pancreatitis in children and adolescents. Indian J Gastroenterol 31:175–178
Glasbrenner B, Adler G (1993) Pathophysiology of acute pancreatitis. Hepatogastroenterology 40:517–521
Glazer G (1975) Haemorrhagic and necrotizing pancreatitis. Br J Surg 62:169–176
Goebell H, Hotz J (1976) Die Ätiologie der akuten Pankreatitis. In: Forell MM (Hrsg) Pankreas, 5. Aufl. Handbuch der Inneren Medizin, Bd. 3/6. Springer, Berlin, S 615–675
Grace RR, Jordan PH Jr. (1976) Unresolved problems of pancreatic pseudocysts. Ann Surg 184:16–21
Gross V, Schoelmerich J, Denzel K, Gerok W (1989) Relapsing pancreatitis as initial manifestation of cystic fibrosis in a young man without pulmonary disease. Int J Pancreatol 4:221–228
Gupta R, Khosroshahi A, Shinagare S, Fernandez C, Ferrone C, Lauwers GY, Stone JH, Deshpande V (2013) Does autoimmune pancreatitis increase the risk of pancreatic carcinoma? A retrospective analysis of pancreatic resections. Pancreas 42:506–510
Gupta RK, Xie BH, Patton KT, Lisovsky M, Burks E, Behrman SW, Klimstra D, Deshpande V (2016) Follicular pancreatitis: a distinct form of chronic pancreatitis – an additional mimic of pancreatic neoplasms. Hum Pathol 48:154–162
Gyr K, Singer MV, Sarles H (1984) Pancreatitis. Concepts and classification. Proceedings of the second international symposium on the classification of pancreatitis. Excerpta Medica, Amsterdam
Hart PA, Kamisawa T, Brugge WR, Chung JB, Culver EL, Czako L, Frulloni L, Go VL, Gress TM, Kim MH, Kawa S, Lee KT, Lerch MM, Liao WC, Lohr M, Okazaki K, Ryu JK, Schleinitz N, Shimizu K, Shimosegawa T, Soetikno R, Webster G, Yadav D, Zen Y, Chari ST (2013) Long-term outcomes of autoimmune pancreatitis: a multicentre, international analysis. Gut 62:1771–1776
Hoffmeister A, Mayerle J, Beglinger C, Buchler MW, Bufler P, Dathe K, Folsch UR, Friess H, Izbicki J, Kahl S, Klar E, Keller J, Knoefel WT, Layer P, Loehr M, Meier R, Riemann JF, Runzi M, Schmid RM, Schreyer A, Tribl B, Werner J, Witt H, Mossner J, Lerch MM (2012) S3-Consensus guidelines on definition, etiology, diagnosis and medical, endoscopic and surgical management of chronic pancreatitis German Society of Digestive and Metabolic Diseases (DGVS). Z Gastroenterol 50:1176–1224
Höfler H (1978) Über die Häufigkeit, Ätiologie und Komplikationen der akuten Pankreatitis – eine retrospektive Studie. Inn Med 5:273–279
Hwang TL, Levy R, Oka M (1980) Pancreatic pseudocyst with unusual complications: perforation of portal and splenic veins and hypersplenism. N Y State J Med 80:252–255
Ikeura T, Takaoka M, Uchida K, Shimatani M, Miyoshi H, Kusuda T, Kurishima A, Fukui Y, Sumimoto K, Satoi S, Ohe C, Uemura Y, Kwon AH, Okazaki K (2012) Autoimmune pancreatitis with histologically proven lymphoplasmacytic sclerosing pancreatitis with granulocytic epithelial lesions. Intern Med 51:733–737
Jacobs ML, Daggett WM, Civette JM, Vasu MA, Lawson DW, Warshaw AL, Nardi GL, Bartlett MK (1977) Acute pancreatitis: analysis of factors influencing survival. Ann Surg 185:43–51
Kamisawa T, Anjiki H, Takuma K, Egawa N, Kubota N (2009) The natural course of autoimmune pancreatitis. Hepatogastroenterology 56:866–870
Kamisawa T, Chari ST, Lerch MM, Kim MH, Gress TM, Shimosegawa T (2014) Republished: recent advances in autoimmune pancreatitis: type 1 and type 2. Postgrad Med J 90:18–25
Klöppel G (1994) Pathology of severe acute pancreatitis. In: Bradley EL (Hrsg) Acute pancreatitis: diagnosis and therapy. Raven Press, New York, S 35–46
Klöppel G (2004) Acute pancreatitis. Semin Diagn Pathol 21:221–226
Klöppel G (2004) Chronic pancreatitis of alcoholic and nonalcoholic origin. Semin Diagn Pathol 21:227–236
Klöppel G (2007) Chronic pancreatitis, pseudotumors and other tumor-like lesions. Mod Pathol 20:S113–S131
Klöppel G, Adsay NV (2009) Chronic pancreatitis and the differential diagnosis versus pancreatic cancer. Arch Pathol Lab Med 133:382–387
Klöppel G, Bommer G, Commandeur G, Heitz P (1978) The endocrine pancreas in chronic pancreatitis. Immunocytochemical and ultrastructural studies. Virchows Arch A Pathol Anat Histol 377:157–174
Klöppel G, Delling G, Knipper A, Heitz PU (1978) Immunocytochemical mapping of pancreatic apudomas in multiple endocrine adenomatosis with primary hyperparathyroidism. Acta Endocrinol 87(Suppl 215):57–58
Klöppel G, Detlefsen S, Chari ST, Longnecker DS, Zamboni G (2010) Autoimmune pancreatitis: the clinicopathological characteristics of the subtype with granulocytic epithelial lesions. J Gastroenterol 45:787–793
Klöppel G, Detlefsen S, Feyerabend B (2004) Fibrosis of the pancreas: the initial tissue damage and the resulting pattern. Virchows Arch 445:1–8
Klöppel G, Dreyer T, Willemer S, Kern HF, Adler G (1986) Human acute pancreatitis: its pathogenesis in the light of immunocytochemical and ultrastructural findings in acinar cells. Virchows Arch A Pathol Anat Histopathol 409:791–803
Klöppel G, Maillet B (1991) Pseudocysts in chronic pancreatitis: a morphological analysis of 57 resection specimens and 9 autopsy pancreata. Pancreas 6:266–274
Klöppel G, Maillet B (1992) The morphological basis for the evolution of acute pancreatitis into chronic pancreatitis. Virchows Arch A Pathol Anat Histopathol 420:1–4
Klöppel G, Maillet B (1993) Pathology of acute and chronic pancreatitis. Pancreas 8:659–670
Klöppel G, von Gerkan R, Dreyer T (1984) Pathomorphology of acute pancreatitis. Analysis of 367 autopsy cases and 3 surgical specimens. In: Gyr KE, Singer MV, Sarles H (Hrsg) Pancreatitis – concepts and classification. Elsevier, Amsterdam, S 29–35
Krag E (1981) Copenhagen pancreatitis study. An interim report from a prospective epidemiological multicentre study. Scand J Gastroenterol 16:305–312
Kulatunga A, Kyllonen AP, Dammert K (1987) Malakoplakia of the pancreas. A case report. Acta Pathol Microbiol Immunol Scand A 95:127–129
Lankisch PG, Lopez E, Winckler K, Schuster R (1976) Kolonveränderungen nach Pankreatitis. Dtsch Med Wochenschr 101:1885–1886
Lerch MM, Saluja AK, Dawra R, Ramarao P, Saluja M, Steer ML (1992) Acute necrotizing pancreatitis in the opossum: earliest morphological changes involve acinar cells. Gastroenterology 103:205–213
Löffler A, Löffler-Bock AH, Friedrichs U (1976) Hyperlipoproteinämie und Pankreatitis. Leber Magen Darm 6:249–252
Löhr JM, Faissner R, Koczan D, Bewerunge P, Bassi C, Brors B, Eils R, Frulloni L, Funk A, Halangk W, Jesenofsky R, Kaderali L, Kleeff J, Kruger B, Lerch MM, Losel R, Magnani M, Neumaier M, Nittka S, Sahin-Toth M, Sanger J, Serafini S, Schnolzer M, Thierse HJ, Wandschneider S, Zamboni G, Klöppel G (2010) Autoantibodies against the exocrine pancreas in autoimmune pancreatitis: gene and protein expression profiling and immunoassays identify pancreatic enzymes as a major target of the inflammatory process. Am J Gastroenterol 105:2060–2071
Löhr M, Klöppel G, Maisonneuve P, Lowenfels AB, Lüttges J (2005) Frequency of K-ras mutations in pancreatic intraductal neoplasias associated with pancreatic ductal adenocarcinoma and chronic pancreatitis: a meta-analysis. Neoplasia 7:17–23
Lowenfels AB, Maisonneuve P, Büchler MW, Friess H, Uhl W, Malfertheiner P (2002) Epidemiology of chronic pancreatitis and the risk of cancerChronic pancreatitis. Novel concepts in biology and therapy. Blackwell Science, Oxford, S 29–36
Lowenfels AB, Maisonneuve P, Cavallini G, Ammann RW, Lankisch PG, Andersen JR, DiMagno EP, Andrén-Sandberg A, Domellöf L, The International Pancreatitis Study Group (1993) Pancreatitis and the risk of pancreatic cancer. N Engl J Med 328:1433–1437
Lowenfels AB, Maisonneuve P, DiMagno EP, Elitsur Y, Gates LK Jr., Perrault J, Whitcomb DC, Group IHPS (1997) Hereditary pancreatitis and the risk of pancreatic cancer. J Natl Cancer Inst 89:442–446
Lurz E, Gonska T (2015) Pancreatic head mass leading to transient obstructive jaundice and diabetes mellitus in an adolescent. Gastroenterology 149:e9–e10
Lüttges J, Diederichs A, Menke MAOH, Vogel I, Kremer B, Klöppel G (2000) Ductal lesions in patients with chronic pancreatitis show K-<i>ras<i> mutations in a frequency similar to that in the normal pancreas and lack nuclear imunoreactivity for p53. Cancer 88:2495–2504
Maher L, Choi H, Dodds WJ (1981) Noncaseating granulomas of the pancreas. Probable sarcoidosis. Am J Gastroenterol 75:222–225
Majumder S, Chari ST (2016) Chronic pancreatitis. Lancet 387:1957–1966
McLatchie GR, Imrie CW (1981) Acute pancreatitis associated with tumour metastases in the pancreas. Digestion 21:13–17
Melville GE, Maxwell DD (1983) Massive lower GI hemorrhage in hemoductal pancreatitis. Gastrointest Radiol 8:145–146
Murphy KP, O’Connor OJ, Maher MM (2014) Updated imaging nomenclature for acute pancreatitis. Am J Roentgenol 203:W464–W469
Nahon Uzan K, Lèvy P, O’Toole D, Belmatoug N, Vullierme MP, Couvelard A, Ponsot P, Palazzo L, Abbas A, Hammel P, Ruszniewski P (2005) Is idiopathic chronic pancreatitis an autoimmune disease? Clin Gastroenterol Hepatol 3:903–909
Nevalainen TJ, Hietaranta AJ, Gronroos JM (1999) Phospholipase A2 in acute pancreatitis: new biochemical and pathological aspects. Hepatogastroenterology 46:2731–2735
Notohara K, Burgart LJ, Yadav D, Chari S, Smyrk TC (2003) Idiopathic chronic pancreatitis with periductal lymphoplasmacytic infiltration: clinicopathologic features of 35 cases. Am J Surg Pathol 27:1119–1127
Nuciforo PG, Moneghini L, Braidotti P, Castoldi L, De Rai P, Bosari S (2003) Malakoplakia of the pancreas with diffuse lymph-node involvement. Virchows Arch 442:82–85
Olsen H (1974) Pancreatitis. A prospective clinical evaluation of 100 cases and review of the literature. Dig Dis Sci 19:1077–1090
Oppenheimer E, Esterly J (1973) Cystic fibrosis of the pancreas. Morphologic findings in infants with and without diagnostic pancreatic lesions. Arch Pathol Lab Med 96:149–154
Paliwal S, Bhaskar S, Chandak GR (2014) Genetic and phenotypic heterogeneity in tropical calcific pancreatitis. World J Gastroenterol 20:17314–17323
Park SH, Kim D, Ye BD, Yang SK, Kim JH, Yang DH, Jung KW, Kim KJ, Byeon JS, Myung SJ, Kim MH, Kim JH (2013) The characteristics of ulcerative colitis associated with autoimmune pancreatitis. J Clin Gastroenterol 47:520–525
Ranson JHC (1982) Etiological and prognostic factors in human acute pancreatitis: a review. Am J Gastroenterol 77:633–638
Read G, Braganza JM, Howat HT (1976) Pancreatitis – a retrospective study. Gut 17:945–952
Rebours V, Levy P, Mosnier JF, Scoazec JY, Soubeyrand MS, Flejou JF, Turlin B, Hammel P, Ruszniewski P, Bedossa P, Couvelard A (2010) Pathology analysis reveals that dysplastic pancreatic ductal lesions are frequent in patients with hereditary pancreatitis. Clin Gastroenterol Hepatol 8:206–212
Renner IG, Savage WT, Pantoja JL, Renner VJ (1985) Death due to acute pancreatitis. A retrospective analysis of 405 autopsy cases. Dig Dis Sci 30:1005–1018
Rodriguez J, Dyck WP (1996) An unusual case of sarcoidosis presenting as a pancreatic mass. Am J Gastroenterol 91:2253–2254
Sakorafas GH, Tsiotos GG, Bower TC, Sarr MG (1998) Ischemic necrotizing pancreatitis. Two case reports and review of the literature. Int J Pancreatol 24:117–121
Sankaran SJ, Xiao AY, Wu LM, Windsor JA, Forsmark CE, Petrov MS (2015) Frequency of progression from acute to chronic pancreatitis and risk factors: a meta-analysis. Gastroenterology 149:1490–1500
Sarles H, Bernard JP, Gullo L (1990) Pathogenesis of chronic pancreatitis. Gut 31:629–632
Sarles H, Laugier R (1981) Alcoholic pancreatitis. Clin Gastroenterol 10:401–415
Sarles H, Sahel J (1976) Pathology of chronic calcifying pancreatitis. Am J Gastroenterol 66:117–139
Sarles H, Sahel J, Forell MM (1976) Die chronische Pankreatitis. In: Beck K et al (Hrsg) Pankreas. Handbuch der Inneren Medizin, Bd. 3/6. Springer, Berlin, S 735–844
Sarti DA (1977) Rapid development and spontaneous regression of pancreatic pseudocysts documented by ultrasound. Radiology 125:789–793
Schmidt H, Lankisch PG (1978) Fat necrosis – a cause of pancreatic parenchymal necrosis? Digestion 17:84–91
Schölzel E, Largiadèr F, Uhlschmid G, Binswanger U, Corrodi P, Knoblauch M (1978) Pankreatitis nach Nierentransplantation. Schweiz Med Wochenschr 108:161–165
Sherman S, Lehman GA (1992) ERCP and endoscopic sphincterotomy-induced pancreatitis. Pancreas 7:42
Shimosegawa T, Chari ST, Frulloni L, Kamisawa T, Kawa S, Mino-Kenudson M, Kim MH, Klöppel G, Lerch MM, Löhr M, Notohara K, Okazaki K, Schneider A, Zhang L (2011) International consensus diagnostic criteria for autoimmune pancreatitis: guidelines of the International Association of Pancreatology. Pancreas 40:352–358
Singhi AD, Pai RK, Kant JA, Bartholow TL, Zeh HJ, Lee KK, Wijkstrom M, Yadav D, Bottino R, Brand RE, Chennat JS, Lowe ME, Papachristou GI, Slivka A, Whitcomb DC, Humar A (2014) The histopathology of PRSS1 hereditary pancreatitis. Am J Surg Pathol 38:346–353
Steinberg W, Tenner S (1994) Acute pancreatitis. N Engl J Med 330:1198–1210
Stock KP, Riemann JF, Stadler W, Rösch W (1981) Tuberculosis of the pancreas. Endoscopy 13:178–180
Stolte M (1984) Chronische Pankreatitis: Morphologie, Pankreatographie, Differentialdiagnose. Perimed, Erlangen
Stolte M, Weiss W, Volkholz H, Rösch W (1982) A special form of segmental pancreatitis: “groove pancreatitis”. Hepatogastroenterology 29:198–208
Storck G, Pettersson G, Edlund Y (1976) A study of autopsies upon 116 patients with acute pancreatitis. Surg Gynecol Obstet 143:241–245
Suzuki S, Homma T, Kurokawa M, Matsukura S, Adachi M, Wakabayashi K, Nozu F, Tazaki T, Kimura T, Matsuura T, Fukuda M, Shiozawa E, Takimoto M (2012) Eosinophilic gastroenteritis due to cow’s milk allergy presenting with acute pancreatitis. Int Arch Allergy Immunol 158(Suppl 1):75–82
Tabata T, Kamisawa T, Hara S, Kuruma S, Chiba K, Kuwata G, Fujiwara T, Egashira H, Koizumi S, Endo Y, Koizumi K, Fujiwara J, Arakawa T, Momma K, Horiguchi S, Hishima T, Kurata M, Honda G, Kloppel G (2013) Intraductal papillary mucinous neoplasm of the pancreas and IgG4-related disease: a coincidental association. Pancreatology 13:379–383
Wanke M, Forell MM (1976) Pathogenese und morphologisches Bild akuter Pankreaserkrankungen. In: Teil 6: Pankreas. Handbuch der Inneren Medizin, Bd. III. Springer, Berlin
Wanke M, Scuro LA, Dagradi A (1981) Morphogenesis of acute pancreatitisTopics in acute and chronic pancreatitis. Springer, Berlin, S 93–113
Warshaw AL, Richter JM, Schapiro RH (1983) The cause and treatment of pancreatitis associated with pancreas divisum. Ann Surg 198:443–452
Whitcomb DC, Gorry MC, Preston RA, Furey W, Sossenheimer MJ, Ulrich CD, Martin SP, Gates LK Jr., Amann ST, Toskes PP, Liddle R, McGrath K, Uomo G, Post JC, Ehrlich GD (1996) Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene. Nat Genet 14:141–145
Whitcomb DC, Preston RA, Aston CE, Sossenheimer MJ, Barua PS, Zhang Y, Wong-Chong A, White GJ, Wood PG, Gates LK Jr., Ulrich C, Martin SP, Post JC, Ehrlich GD (1996) A gene for hereditary pancreatitis maps to chromosome 7q35. Gastroenterology 110:1975–1980
Witt H, Bhatia E (2008) Genetic aspects of tropical calcific pancreatitis. Rev Endocr Metab Disord 9:213–226
Yao Y, Jiang F, Jin Z (2016) Pancreatic sarcoidosis in association with type 1 autoimmune pancreatitis: a case report and literature review. Pancreas 45:e7–e8
Zamboni G, Capelli P, Scarpa A, Bogina G, Pesci A, Brunello E, Klöppel G (2009) Nonneoplastic mimickers of pancreatic neoplasms. Arch Pathol Lab Med 133:439–453
Zamboni G, Lüttges J, Capelli P, Frulloni L, Cavallini G, Pederzoli P, Leins A, Longnecker D, Klöppel G (2004) Histopathological features of diagnostic and clinical relevance in autoimmune pancreatitis: a study on 53 resection specimens and 9 biopsy specimens. Virchows Arch 445:552–563
Zen Y, Grammatikopoulos T, Heneghan MA, Vergani D, Mieli-Vergani G, Portmann BC (2012) Sclerosing cholangitis with granulocytic epithelial lesion: a benign form of sclerosing cholangiopathy. Am J Surg Pathol 36:1555–1561
Zen Y, Ishikawa A, Ogiso S, Heaton N, Portmann B (2012) Follicular cholangitis and pancreatitis – clinicopathological features and differential diagnosis of an under-recognized entity. Histopathology 60:261–269
Zhan X, Wang F, Bi Y, Ji B (2016) Animal models of acute and chronic pancreatitis. Am J Physiol Gastrointest Liver Physiol 311:G343–G355
Zuk RJ, Neal JW, Baithun SI (1990) Malakoplakia of the pancreas. Virchows Arch A Pathol Anat Histopathol 417:181–184
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Klöppel, G., Lüttges, J., Sipos, B. (2020). Pankreatitis. In: Tannapfel, A., Klöppel, G. (eds) Pathologie. Pathologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-04557-8_22
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