A Comparative Analysis of SPECT Images of the Left and Right Cerebral Hemispheres in Patients with Diagnosed Epileptic Symptoms

Abstract

The aim of his work was examination of asymmetries in activity of the left and right cerebral hemispheres as well as localization and contouring of the regions of reduced or increased activity on the basis of single photon emission computer tomography (SPECT) images. Advantage of this technique lies in possibility of brain activity map acquisition at the time of radiotracer injection during seizures though the image registration is done one hour after seizure. The SPECT imaging method makes possible a more accurate spatial localization of seizure source than analysis of EEG signals. Simultaneous EEG signal registration allows to qualify exactly the moment of seizure onset when radiotracer injection could be done to register an unequivocal image. The mean and standard deviation of normalized intensities inside the contoured areas of images were calculated.