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A Comparative Proteomic Analysis of Low Shear Stress Induced Vascular Remolding: Regulation of Lysyl Oxidase and TGF-Beta

  • Conference paper
World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany

Part of the book series: IFMBE Proceedings ((IFMBE,volume 25/4))

  • 88 Accesses

Abstract

Blood flow induced shear stress, especially the low shear stress, is a crucial stressor for vascular remodeling during atherogenesis [1], which involved migration, proliferation and apoptosis of vascular smooth muscle cells (VSMCs) [2]. The researches on the molecular mechanisms of low shear stress induced vascular remodeling could contribute to finding a new target in the prevention and treatment of atherosclerosis.

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Authors and Affiliations

  1. Institute of Mechanobiology & Medical Engineering, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China

    Ying-Xin Qi, Xiao-Dong Wang, Jun Jiang, Xiao-Hua Jiang, Su-Ying Ji, Ding-Kun Long & Zong-Lai Jiang

Authors
  1. Ying-Xin Qi
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  2. Xiao-Dong Wang
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  3. Jun Jiang
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  4. Xiao-Hua Jiang
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  5. Su-Ying Ji
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  6. Ding-Kun Long
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  7. Zong-Lai Jiang
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Editor information

Editors and Affiliations

  1. Inst. Biomedizinische Technik, Univ. Karlsruhe, Kaiserstr. 12, 76128, Karlsruhe, Germany

    Olaf Dössel

  2. Abt. Medizinische Physik in der Strahlentherapie, Deutsche Krebsforschungszentrum (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany

    Wolfgang C. Schlegel

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© 2009 Springer-Verlag Berlin Heidelberg

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Qi, YX. et al. (2009). A Comparative Proteomic Analysis of Low Shear Stress Induced Vascular Remolding: Regulation of Lysyl Oxidase and TGF-Beta. In: Dössel, O., Schlegel, W.C. (eds) World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany. IFMBE Proceedings, vol 25/4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03882-2_41

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  • DOI: https://doi.org/10.1007/978-3-642-03882-2_41

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-03881-5

  • Online ISBN: 978-3-642-03882-2

  • eBook Packages: EngineeringEngineering (R0)

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