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Phototoxic and Photoallergic Reactions

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Contact Dermatitis

Abstract

Phototoxic and photoallergic reactions represent skin reactions to the sun, in the presence of photoactive chemicals applied on the skin or taken systemically. They have a highly polymorphic clinical presentation – photocontact urticaria, eczema on sun-exposed areas sometimes with erythema multiforme, exaggerated sunburn, linear phytophotodermatitis, pseudoporphyria, photoonycholysis, dyschromia, and lupus erythematosus. Also, skin cancers are increasingly associated with exposure to photoactive chemicals. There is a geographical and timely variation in the responsible agents, but they are mostly furocumarins from plants, UV filters in sunscreens and cosmetics, and drugs (NSAIDs, antimicrobials, phenothiazines, amiodarone, etc.).

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Authors and Affiliations

  1. Clinic of Dermatology, Coimbra University Hospital, University of Coimbra, Praceta Mota Pinto, 3000-175, Coimbra, Portugal

    Margarida Gonçalo

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  1. Margarida Gonçalo
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Correspondence to Margarida Gonçalo .

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  1. Dept. Dermatology, Amtssygehuset Gentofte, Niels Andersens Vej 65, Hellerup, 2900, Denmark

    Jeanne Duus Johansen

  2. Klinikzentrum Mitte, Hautklinik, Städtische Kliniken Dortmund, Beurhausstr. 40, Dortmund, 44137, Germany

    Peter J. Frosch

  3. Labo. Dermatochimie, Institut le Bel, rue Blaise Pascal 4, Strasbourg CX, 67070, France

    Jean-Pierre Lepoittevin

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Gonçalo, M. (2011). Phototoxic and Photoallergic Reactions. In: Johansen, J., Frosch, P., Lepoittevin, JP. (eds) Contact Dermatitis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03827-3_18

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