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Molekulare Pathogenese, Diagnostik und Therapie hereditärer Tumoren des Gastrointestinaltrakts

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Book cover Praxis der Viszeralchirurgie Onkologische Chirurgie

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Zusammenfassung

Die Aufklärung der molekulargenetischen Grundlagen der Krebsentstehung hat in den letzten Jahren wesentliche neue Erkenntnisse erbracht, durch die es möglich geworden ist, Patienten mit einem erblich bedingten erhöhten Krebsrisiko durch genetische Untersuchungsmethoden zu identifizieren. Insbesondere bei den erblichen gastrointestinalen Tumorprädispositionssyndromen, allen voran der familiären adenomatösen Polyposis (FAP) und dem hereditären nichtpolypösen kolorektalen Karzinom (HNPCC) konnten so neue interdisziplinäre klinische Konzepte entwickelt werden, die zu einer wesentlichen Verbesserung der Krebsvorsorge und -früherkennung beitragen.

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Authors and Affiliations

  1. Pathologisches Institut, Abt. für angewandte Tumorbiologie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 220/221, 69120, Heidelberg

    Dr. med. M. Kloor, Prof. Dr. med. M. von Knebel Doeberitz & Dr. rer. nat. J. Gebert

Authors
  1. Dr. med. M. Kloor
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  2. Prof. Dr. med. M. von Knebel Doeberitz
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  3. Dr. rer. nat. J. Gebert
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Editors and Affiliations

  1. Universitätsklinikum Heidelberg, Im Neuenheimer Feld 672, 69120, Heidelberg

    J. R. Siewert (Leitender Ärztlicher Direktor und Vorstandsvorsitzender) (Leitender Ärztlicher Direktor und Vorstandsvorsitzender)

  2. Zentrum für Operative Medizin I, Klinikum der Philipps-Universität, Baldinger Straße, 35043, Marburg

    Matthias Rothmund

  3. Universitätsklinik und Poliklinik, Medizinische Fakultät der RWTH, Pauwelsstraße 30, 52057, Aachen

    Volker Schumpelick

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Kloor, M., von Knebel Doeberitz, M., Gebert, J. (2010). Molekulare Pathogenese, Diagnostik und Therapie hereditärer Tumoren des Gastrointestinaltrakts. In: Siewert, J.R., Rothmund, M., Schumpelick, V. (eds) Praxis der Viszeralchirurgie Onkologische Chirurgie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03808-2_5

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  • DOI: https://doi.org/10.1007/978-3-642-03808-2_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-03807-5

  • Online ISBN: 978-3-642-03808-2

  • eBook Packages: Medicine (German Language)

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