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Ösophaguskarzinom

  • Chapter
Praxis der Viszeralchirurgie Onkologische Chirurgie

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Zusammenfassung

Aus epidemiologischer und tumorbiologischer Sicht muss zwischen Plattenepithel- und Adenokarzinomen der Speiseröhre unterschieden werden. Die grundsätzlichen chirurgischen Therapieprinzipien sind allerdings für beide Tumoren ähnlich. Bei beiden gilt die R0-Resektion als wesentliches chirurgisches Therapieziel. Dieses kann bei T1- und T2-Tumoren sicher erreicht werden. Bei lokal fortgeschrittenen Tumoren (T3 und T4) werden derzeitig neoadjuvante Therapieprinzipien erprobt. Von dieser Therapie profitieren Patienten, die auf die Vorbehandlung mit einer Tumorreduktion („Downsizing “ oder gar „Down-Staging“) ansprechen. So genannte „Non-Responder“ haben eine schlechte Prognose. Ihnen steht nur eine palliative Therapie zur Verfügung.

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Authors and Affiliations

  1. Universitätsklinikum Heidelberg, Im Neuenheimer Feld 672, 69120, Heidelberg

    Prof. Dr. med. Dr. h.c. J. R. Siewert (Leitender Ärztlicher Direktor und Vorstandsvorsitzender)

  2. Chirurgische Klinik, Klinikum Nürnberg-Nord, Ernst-Nathan-Straße 1/Haus 20, 90419, Nürnberg

    Univ.-Prof. Dr. med. H. J. Stein

  3. Medizinische Klinik III, Hämatologie und Onkologie, Klinikum Braunschweig, Celler Straße 38, 38114, Braunschweig

    Prof. Dr. med. F. Lordick

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  1. Prof. Dr. med. Dr. h.c. J. R. Siewert
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  2. Univ.-Prof. Dr. med. H. J. Stein
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  3. Prof. Dr. med. F. Lordick
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Editors and Affiliations

  1. Universitätsklinikum Heidelberg, Im Neuenheimer Feld 672, 69120, Heidelberg

    J. R. Siewert (Leitender Ärztlicher Direktor und Vorstandsvorsitzender) (Leitender Ärztlicher Direktor und Vorstandsvorsitzender)

  2. Zentrum für Operative Medizin I, Klinikum der Philipps-Universität, Baldinger Straße, 35043, Marburg

    Matthias Rothmund

  3. Universitätsklinik und Poliklinik, Medizinische Fakultät der RWTH, Pauwelsstraße 30, 52057, Aachen

    Volker Schumpelick

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Siewert, J.R., Stein, H.J., Lordick, F. (2010). Ösophaguskarzinom. In: Siewert, J.R., Rothmund, M., Schumpelick, V. (eds) Praxis der Viszeralchirurgie Onkologische Chirurgie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03808-2_38

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  • DOI: https://doi.org/10.1007/978-3-642-03808-2_38

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-03807-5

  • Online ISBN: 978-3-642-03808-2

  • eBook Packages: Medicine (German Language)

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