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Praxis der Viszeralchirurgie Onkologische Chirurgie pp 167–173Cite as

Wächterlymphknotendetektion

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Zusammenfassung

Die klinische Einführung des Sentinel-Lymphknotenkonzepts erfolgte 1992 durch Morton et al. mit der Detektion von Lymphknotenmetastasen beim malignen Melanom. Giuliano et al. wandten das Verfahren ab 1994 auch beim Mammakarzinom an. Mittlerweile wurde die Validität des Sentinel- Lymphknotenkonzepts für das maligne Melanom und das Mammakarzinom in zahlreichen groß angelegten Studien belegt (Morton et al. 2005; Veronesi et al. 2003). Bei diesen Tumoren der Hautoberfläche ist inzwischen das Sentinelnode-Konzept fest in der klinischen Routine etabliert. Bei beiden Tumorentitäten wird bei negativem Sentinel-Lymphknoten eine systematische Lymphadenektomie nicht mehr durchgeführt.

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Authors and Affiliations

  1. Direktor der Chirurgischen Klinik Marienhospital Herne, Klinikum der Ruhr-Universität Bochum, Hölkeskampring 40, 44625, Herne

    Univ.-Prof. Dr. med. A. Sendler

Authors
  1. Univ.-Prof. Dr. med. A. Sendler
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Editors and Affiliations

  1. Universitätsklinikum Heidelberg, Im Neuenheimer Feld 672, 69120, Heidelberg

    J. R. Siewert (Leitender Ärztlicher Direktor und Vorstandsvorsitzender) (Leitender Ärztlicher Direktor und Vorstandsvorsitzender)

  2. Zentrum für Operative Medizin I, Klinikum der Philipps-Universität, Baldinger Straße, 35043, Marburg

    Matthias Rothmund

  3. Universitätsklinik und Poliklinik, Medizinische Fakultät der RWTH, Pauwelsstraße 30, 52057, Aachen

    Volker Schumpelick

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Sendler, A. (2010). Wächterlymphknotendetektion. In: Siewert, J.R., Rothmund, M., Schumpelick, V. (eds) Praxis der Viszeralchirurgie Onkologische Chirurgie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03808-2_15

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  • DOI: https://doi.org/10.1007/978-3-642-03808-2_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-03807-5

  • Online ISBN: 978-3-642-03808-2

  • eBook Packages: Medicine (German Language)

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