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Nuklearmedizinische Diagnostik

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Praxis der Viszeralchirurgie Onkologische Chirurgie

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Zusammenfassung

Nuklearmedizinische Verfahren erlauben es, bei Patienten physiologische und biochemische Prozesse zu messen. Dazu werden verschiedene Testsubstanzen (Marker, Tracer) eingesetzt, deren Verteilung im Organismus durch die Markierung mit einem radioaktiven Nuklid mit Hilfe eines externen Detektorsystems bestimmt wird. Da aufgrund der hohen Empfindlichkeit nur sehr geringe Mengen dieser Marker (Spürdosis) eingesetzt werden, wird der zu untersuchende Prozess nicht beeinflusst und es können keine pharmakologischen oder toxischen Wirkungen auftreten. Nuklearmedizinische Verfahren ermöglichen es, Tumorgewebe spezifisch z. B. durch den Nachweis von Stoffwechselprozessen, Rezeptoren oder Antigenen bildlich darzustellen und zu quantifizieren (molekulare Bildgebung). Bei der molekularen Bildgebung liegt dem gemessenen Bildsignal eine spezifische biologische Eigenschaft des Tumors zugrunde — im Gegensatz zu morphologisch bildgebenden Verfahren, die die Dichte des Gewebes und seine Gefäßpermeabilität darstellen.

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Author information

Authors and Affiliations

  1. Klinik für Nuklearmedizin, Klinikum rechts der Isar der TU München, Ismaninger Straße 22, 81675, München

    Prof. Dr. med. B. J. Krause, Dr. med. K. Herrmann & Univ.-Prof. Dr. med. M. Schwaiger

  2. Chirurgische Klinik, UniversitMätsklinikum Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg

    Prof. Dr. med. K. Ott

  3. III. Medizinische Klink, Klinikum rechts der Isar der TU München, Ismaninger Straße 22, 81675, München

    Priv.-Doz. Dr. med. C. Meyer zum Büschenfelde

Authors
  1. Prof. Dr. med. B. J. Krause
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  2. Dr. med. K. Herrmann
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  3. Prof. Dr. med. K. Ott
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  4. Priv.-Doz. Dr. med. C. Meyer zum Büschenfelde
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  5. Univ.-Prof. Dr. med. M. Schwaiger
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Editor information

Editors and Affiliations

  1. Universitätsklinikum Heidelberg, Im Neuenheimer Feld 672, 69120, Heidelberg

    J. R. Siewert (Leitender Ärztlicher Direktor und Vorstandsvorsitzender) (Leitender Ärztlicher Direktor und Vorstandsvorsitzender)

  2. Zentrum für Operative Medizin I, Klinikum der Philipps-Universität, Baldinger Straße, 35043, Marburg

    Matthias Rothmund

  3. Universitätsklinik und Poliklinik, Medizinische Fakultät der RWTH, Pauwelsstraße 30, 52057, Aachen

    Volker Schumpelick

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Krause, B.J., Herrmann, K., Ott, K., Meyer zum Büschenfelde, C., Schwaiger, M. (2010). Nuklearmedizinische Diagnostik. In: Siewert, J.R., Rothmund, M., Schumpelick, V. (eds) Praxis der Viszeralchirurgie Onkologische Chirurgie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03808-2_13

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  • DOI: https://doi.org/10.1007/978-3-642-03808-2_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-03807-5

  • Online ISBN: 978-3-642-03808-2

  • eBook Packages: Medicine (German Language)

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