Abstract
Sickle cell disease (SCD) is an autosomal recessive genetic disorder, characterized by episodic attacks of hemolytic anemia and vaso-occlusive attacks due to “sickeling” of the red blood cells (RBCs) under certain body conditions that include dehydration, metabolic acidosis, and low oxygen saturation.
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For Further Reading
Lonergan GJ et al Sickle cell anemia. RadioGraphics. 2001; 21:971–94
Ejindu VG et al Musculoskeletal manifestations of sickle cell disease. RadioGraphics. 2007;27:1005–21
Schatz J et al Sickle cell disease as a neurodevelopmental disorder. Ment Retard Dev Disabil Res Rev. 2006;12:200–7
John N. Lukens. Sickle cell disease. Dis Mon. 1981;27:1–56
Babhulkar SS et al The hand-foot syndrome in sickle-cell haemoglobinopathy. J Bone Joint Surg (Br). 1995;77-B:310–2
Janet Watson R et al The hand-foot syndrome in sickle-cell disease in young children. Pediatrics. 1963;31;975–82
John N. Lukens. Sickle cell disease. Dis Mon. 1981;27:1–56
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Al-Tubaikh, J.A. (2010). Sickle Cell Disease. In: Al-Tubaikh, J.A. (eds) Internal Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03709-2_57
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DOI: https://doi.org/10.1007/978-3-642-03709-2_57
Publisher Name: Springer, Berlin, Heidelberg
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