Skip to main content

On Stability of Limit Cycles of a Prototype Problem of Piecewise Linear Systems

  • Chapter
Emergent Problems in Nonlinear Systems and Control

Part of the book series: Lecture Notes in Control and Information Sciences ((LNCIS,volume 393))

  • 824 Accesses

Summary

The purpose of this paper is to develop a machinery to analyze existence and stability of limit cycle of a prototype of piecewise linear systems, possibly with delays in switching rules. The study of this type of problems is motivated by modelling cell cycle regulation. The results are applied to a cell cycle model of fission yeast. It is shown that the cell cycle model has a limit cycle and it is stable and criterion of the stability regions are also given.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Novak, B., Pataki, Z., Ciliberto, A., Tyson, J.J.: Mathematical model of the cell division cycle of fission yeast. Chaos 11, 277–286 (2001)

    Article  MATH  Google Scholar 

  2. Eriksson, O., Zhou, Y., Tegner, J.: Modeling complex cellular networks - Robust switching in the cell cycle ensures a piecewise linear reduction of the regulatory network. In: Proc. of the IEEE Conference on Decision and Control, vol. 1, pp. 117–123 (2004)

    Google Scholar 

  3. Eriksson, O., Brinne, B., Zhou, Y., Björkegren, J., Tegnér, J.: Deconstructing the core dynamics from a complex time-lagged regulatory biological circuit. IET Syst. Biol. 3, 113–129 (2009)

    Article  Google Scholar 

  4. Gonçalves, J.M.: Region of stability for limit cycles of piecewise linear systems. In: Proc. of the IEEE Conference on Decision and Control (2003)

    Google Scholar 

  5. Gonçalves, J.M., Megretski, A., Dahleh, M.A.: Global analysis of limit cycles of piecewise linear systems using impact maps and surface Lyapunov functions. IEEE Trans. Automat. Contr. 48, 2089–2106 (2003)

    Article  Google Scholar 

  6. Hale, J.K.: Theory of functional differential equations. Springer, New York (1997)

    Google Scholar 

  7. Monk, N.A.M.: Oscillatory expression of Hes1, p53, and NF-κB driven by transcriptal time delays. Curr. Biol. 13, 1409–1413 (2003)

    Article  Google Scholar 

  8. Tyson, J.J., Hong, C.I., Thron, C.D., Novak, B.: A simple model of circadian rhythms based on dimerization and proteolysis of PER and TIM. Biophys J. 77, 2411–2417 (1999)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2009 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Eriksson, O., Tègner, J., Zhou, Y. (2009). On Stability of Limit Cycles of a Prototype Problem of Piecewise Linear Systems. In: Ghosh, B.K., Martin, C.F., Zhou, Y. (eds) Emergent Problems in Nonlinear Systems and Control. Lecture Notes in Control and Information Sciences, vol 393. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03627-9_3

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-03627-9_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-03626-2

  • Online ISBN: 978-3-642-03627-9

  • eBook Packages: EngineeringEngineering (R0)

Publish with us

Policies and ethics